"Relaxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A water-soluble polypeptide (molecular weight approximately 8,000) extractable from the corpus luteum of pregnancy. It produces relaxation of the pubic symphysis and dilation of the uterine cervix in certain animal species. Its role in the human pregnant female is uncertain. (Dorland, 28th ed)
| Descriptor ID |
D012065
|
| MeSH Number(s) |
D06.472.334.734.769 D06.472.699.715 D12.644.548.762
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Relaxin".
Below are MeSH descriptors whose meaning is more specific than "Relaxin".
This graph shows the total number of publications written about "Relaxin" by people in this website by year, and whether "Relaxin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Relaxin" by people in Profiles.
-
Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology. Biochem Pharmacol. 2024 09; 227:116401.
-
Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2. Commun Biol. 2022 11 04; 5(1):1183.
-
Targeting the relaxin/insulin-like family peptide receptor 1 and 2 with small molecule compounds. Mol Cell Endocrinol. 2019 05 01; 487:40-44.
-
Evidence of altered brain regulatory gene expression in tobacco-exposed fetuses. J Perinat Med. 2017 Dec 20; 45(9):1045-1053.
-
ML290 is a biased allosteric agonist at the relaxin receptor RXFP1. Sci Rep. 2017 06 07; 7(1):2968.
-
Relaxin-like peptides in male reproduction - a human perspective. Br J Pharmacol. 2017 05; 174(10):990-1001.
-
Relaxin-2 and Soluble Flt1 Levels in Peripartum Cardiomyopathy: Results of the Multicenter IPAC Study. JACC Heart Fail. 2016 05; 4(5):380-8.
-
Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists. Biochemistry. 2016 Mar 29; 55(12):1772-83.
-
Heart failure with preserved ejection fraction in the elderly: scope of the problem. J Mol Cell Cardiol. 2015 Jun; 83:73-87.
-
Relaxin for treatment of acute heart failure: making the case for treating targeted patient profiles. Curr Heart Fail Rep. 2013 Sep; 10(3):198-203.