"Urocortins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.
| Descriptor ID |
D054832
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| MeSH Number(s) |
D06.472.699.857 D12.644.400.837 D12.644.548.887
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Urocortins".
Below are MeSH descriptors whose meaning is more specific than "Urocortins".
This graph shows the total number of publications written about "Urocortins" by people in this website by year, and whether "Urocortins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Urocortins" by people in Profiles.
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Identification of novel enriched recurrent chimeric COL7A1-UCN2 in human laryngeal cancer samples using deep sequencing. BMC Cancer. 2018 03 02; 18(1):248.
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Urocortin II mediates pro-inflammatory effects in human colonocytes via corticotropin-releasing hormone receptor 2alpha. Gut. 2007 Sep; 56(9):1210-7.
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Urocortin-deficient mice display normal stress-induced anxiety behavior and autonomic control but an impaired acoustic startle response. Mol Cell Biol. 2002 Sep; 22(18):6605-10.
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Urocortin in the synovial tissue of patients with rheumatoid arthritis. Clin Sci (Lond). 2001 Jun; 100(6):577-89.
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Urocortin and corticotropin-releasing factor receptor expression in normal cycling human ovaries. J Clin Endocrinol Metab. 2001 Mar; 86(3):1362-9.
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Urocortin and corticotropin-releasing factor receptor expression in the human colonic mucosa. Peptides. 2000 Dec; 21(12):1799-809.
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Corticotropin releasing hormone and related peptides can act as bioregulatory factors in human keratinocytes. In Vitro Cell Dev Biol Anim. 2000 Mar; 36(3):211-6.
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The skin produces urocortin. J Clin Endocrinol Metab. 2000 Feb; 85(2):815-23.
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Urocortin expression in the human central nervous system. Clin Endocrinol (Oxf). 1999 Jan; 50(1):107-14.
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Urocortin expression in human pituitary gland and pituitary adenoma. J Clin Endocrinol Metab. 1997 Nov; 82(11):3842-50.