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WILLIAM BROWNELL

TitleProfessor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Otolaryngology-Head and Neck Surgery
Address1977 BUTLER BLVD
HOUSTON, TX 77030
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    Other Positions
    TitleProfessor Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Integrative Physiology
    DivisionMolecular Physiology & Biophysics

    TitleProfessor Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience


    Collapse Research 
    Collapse research activities and funding
    S10RR027549     (BROWNELL, WILLIAM E)Jul 20, 2010 - Jul 19, 2011
    NIH
    Biophysics Cell Membrane Probe
    Role: Principal Investigator
    T32DC007367     (BROWNELL, WILLIAM E)Jul 1, 2005 - Jun 30, 2010
    NIH
    Research Training in Otolaryngology Head &Neck Surgery
    Role: Principal Investigator
    R01DC002775     (BROWNELL, WILLIAM E)May 1, 1996 - May 30, 2012
    NIH
    Electromechanics of the Cochlear Outer Hair Cell
    Role: Principal Investigator
    R01DC000354     (BROWNELL, WILLIAM E)Apr 1, 1986 - Jul 31, 2020
    NIH
    Intracochlear Electrochemical Gradients
    Role: Principal Investigator
    R01NS023567     (BROWNELL, WILLIAM E)Apr 1, 1986 - Mar 31, 1990
    NIH
    INTRACOCHLEAR ELECTRO-CHEMICAL GRADIENTS
    Role: Principal Investigator
    R01NS023692     (BROWNELL, WILLIAM E)Jan 1, 1986 - Jun 30, 1986
    NIH
    NEURAL COMMUNICATION IN HEARING: A BRAINSTEM FIBER STUD
    Role: Principal Investigator
    R01NS019050     (BROWNELL, WILLIAM E)Jan 1, 1983 - Aug 31, 1985
    NIH
    NEURAL COMMUNICATION IN HEARING: BRAINSTEM FIBER STUDY
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Farrell B, Skidmore BL, Rajasekharan V, Brownell WE. A novel theoretical framework reveals more than one voltage-sensing pathway in the lateral membrane of outer hair cells. J Gen Physiol. 2020 07 06; 152(7). PMID: 32384538; PMCID: PMC7335013.
      Citations: 1     Fields:    Translation:Cells
    2. de Monvel JB, Brownell WE, Ulfendahl M. Lateral Diffusion Anisotropy and Membrane Lipid/Skeleton Interaction in Outer Hair Cells. Biophys J. 2018 06 05; 114(11):2756. PMID: 29874623; PMCID: PMC6129555.
      Citations:    Fields:    
    3. Brownell WE. What Is Electromotility? -The History of Its Discovery and Its Relevance to Acoustics. Acoust Today. 2017; 13(1):20-27. PMID: 29051713; PMCID: PMC5645053.
      Citations: 6     
    4. Seymour ML, Rajagopalan L, Duret G, Volk MJ, Liu H, Brownell WE, Pereira FA. Membrane prestin expression correlates with the magnitude of prestin-associated charge movement. Hear Res. 2016 09; 339:50-9. PMID: 27262187; PMCID: PMC5018423.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    5. Araya M, Brownell WE. Nanotechnology in Auditory Research: Membrane Electromechanics in Hearing. Methods Mol Biol. 2016; 1427:349-62. PMID: 27259937; PMCID: PMC4988393.
      Citations:    Fields:    Translation:AnimalsCells
    6. Yamashita T, Wu S, Hassan A, Jacob S, Temirov J, Fang J, Mellado-Lagarde M, Gursky R, Horner L, Leibiger B, Leijon S, Centonze VE, Berggren PO, Frase S, Auer M, Brownell WE, Zuo J, Hakizimana P, Fridberger A. Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins. PLoS Genet. 2015 Sep; 11(9):e1005500. PMID: 26352669; PMCID: PMC4564264.
      Citations: 17     Fields:    Translation:AnimalsCells
    7. Harland B, Lee WH, Brownell WE, Sun SX, Spector AA. The potential and electric field in the cochlear outer hair cell membrane. Med Biol Eng Comput. 2015 May; 53(5):405-13. PMID: 25687712; PMCID: PMC4823141.
      Citations: 1     Fields:    Translation:AnimalsCells
    8. Powers RJ, Kulason S, Atilgan E, Brownell WE, Sun SX, Barr-Gillespie PG, Spector AA. The local forces acting on the mechanotransduction channel in hair cell stereocilia. Biophys J. 2014 Jun 03; 106(11):2519-28. PMID: 24896132; PMCID: PMC4052279.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    9. Khatibzadeh N, Spector AA, Brownell WE, Anvari B. Effects of plasma membrane cholesterol level and cytoskeleton F-actin on cell protrusion mechanics. PLoS One. 2013; 8(2):e57147. PMID: 23451167; PMCID: PMC3579816.
      Citations: 22     Fields:    Translation:HumansCells
    10. Farrell B, Qian F, Kolomeisky A, Anvari B, Brownell WE. Measuring forces at the leading edge: a force assay for cell motility. Integr Biol (Camb). 2013 Jan; 5(1):204-14. PMID: 23080534; PMCID: PMC3529002.
      Citations: 8     Fields:    Translation:AnimalsCells
    11. Khatibzadeh N, Gupta S, Farrell B, Brownell WE, Anvari B. Effects of cholesterol on nano-mechanical properties of the living cell plasma membrane. Soft Matter. 2012; 8(32):8350-8360. PMID: 23227105; PMCID: PMC3515074.
      Citations: 30     Fields:    
    12. Corbitt C, Farinelli F, Brownell WE, Farrell B. Tonotopic relationships reveal the charge density varies along the lateral wall of outer hair cells. Biophys J. 2012 Jun 20; 102(12):2715-24. PMID: 22735521; PMCID: PMC3379021.
      Citations: 10     Fields:    Translation:AnimalsCells
    13. Roy S, Brownell WE, Spector AA. Modeling electrically active viscoelastic membranes. PLoS One. 2012; 7(5):e37667. PMID: 22701528; PMCID: PMC3365126.
      Citations: 3     Fields:    Translation:Cells
    14. Lau C, Brownell WE, Spector AA. Internal forces, tension and energy density in tethered cellular membranes. J Biomech. 2012 Apr 30; 45(7):1328-31. PMID: 22342157.
      Citations: 3     Fields:    Translation:Cells
    15. Powers RJ, Roy S, Atilgan E, Brownell WE, Sun SX, Gillespie PG, Spector AA. Stereocilia membrane deformation: implications for the gating spring and mechanotransduction channel. Biophys J. 2012 Jan 18; 102(2):201-10. PMID: 22339856; PMCID: PMC3260783.
      Citations: 25     Fields:    Translation:AnimalsCells
    16. Hakizimana P, Brownell WE, Jacob S, Fridberger A. Sound-induced length changes in outer hair cell stereocilia. Nat Commun. 2012; 3:1094. PMID: 23033070; PMCID: PMC3594849.
      Citations: 21     Fields:    Translation:AnimalsCells
    17. Rabbitt RD, Brownell WE. Efferent modulation of hair cell function. Curr Opin Otolaryngol Head Neck Surg. 2011 Oct; 19(5):376-81. PMID: 22552698; PMCID: PMC3343276.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    18. Brownell WE, Jacob S, Hakizimana P, Ulfendahl M, Fridberger A. Membrane cholesterol modulates cochlear electromechanics. Pflugers Arch. 2011 Jun; 461(6):677-86. PMID: 21373862; PMCID: PMC3098987.
      Citations: 19     Fields:    Translation:AnimalsCells
    19. Nilsen N, Brownell WE, Sun SX, Spector AA. Effect of membrane mechanics on charge transfer by the membrane protein prestin. Biomech Model Mechanobiol. 2012 Jan; 11(1-2):107-18. PMID: 21365198; PMCID: PMC3158267.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    20. Brownell WE, Qian F, Anvari B. Cell membrane tethers generate mechanical force in response to electrical stimulation. Biophys J. 2010 Aug 04; 99(3):845-52. PMID: 20682262; PMCID: PMC3297770.
      Citations: 21     Fields:    Translation:HumansCells
    21. Ashmore J, Avan P, Brownell WE, Dallos P, Dierkes K, Fettiplace R, Grosh K, Hackney CM, Hudspeth AJ, Lindner B, Martin P, Meaud J, Petit C, Santos-Sacchi J, Sacchi JR, Canlon B, J?licher F. The remarkable cochlear amplifier. Hear Res. 2010 07; 266(1-2):1-17. PMID: 20541061; PMCID: PMC6366996.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    22. Harland B, Brownell WE, Spector AA, Sun SX. Voltage-induced bending and electromechanical coupling in lipid bilayers. Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Mar; 81(3 Pt 1):031907. PMID: 20365770.
      Citations: 4     Fields:    
    23. Brownell WE. WITHDRAWN: Membrane-based amplification in hearing. Hear Res. 2010 Jan 30. PMID: 20123061.
      Citations:    Fields:    
    24. Rajagopalan L, Organ-Darling LE, Liu H, Davidson AL, Raphael RM, Brownell WE, Pereira FA. Glycosylation regulates prestin cellular activity. J Assoc Res Otolaryngol. 2010 Mar; 11(1):39-51. PMID: 19898896; PMCID: PMC2820205.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    25. Brownell WE. WITHDRAWN: Membrane-based amplification in hearing. Hear Res. 2009 Oct 07. PMID: 19818390; PMCID: PMC2888686.
      Citations:    Fields:    
    26. Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA. Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Oct; 80(4 Pt 1):041905. PMID: 19905340; PMCID: PMC4990357.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    27. Sachs F, Brownell WE, Petrov AG. Membrane Electromechanics in Biology, with a Focus on Hearing. MRS Bull. 2009 Sep 01; 34(9):665. PMID: 20165559; PMCID: PMC2822359.
      Citations: 11     
    28. Gliko O, Saggau P, Brownell WE. Compartmentalization of the outer hair cell demonstrated by slow diffusion in the extracisternal space. Biophys J. 2009 Aug 19; 97(4):1215-24. PMID: 19686670; PMCID: PMC2726316.
      Citations:    Fields:    Translation:Cells
    29. Rabbitt RD, Clifford S, Breneman KD, Farrell B, Brownell WE. Power efficiency of outer hair cell somatic electromotility. PLoS Comput Biol. 2009 Jul; 5(7):e1000444. PMID: 19629162; PMCID: PMC2705677.
      Citations: 33     Fields:    Translation:AnimalsCells
    30. Sun SX, Farrell B, Chana MS, Oster G, Brownell WE, Spector AA. Voltage and frequency dependence of prestin-associated charge transfer. J Theor Biol. 2009 Sep 07; 260(1):137-44. PMID: 19490917; PMCID: PMC2753271.
      Citations: 11     Fields:    Translation:HumansCells
    31. Breneman KD, Brownell WE, Rabbitt RD. Hair cell bundles: flexoelectric motors of the inner ear. PLoS One. 2009; 4(4):e5201. PMID: 19384413; PMCID: PMC2668172.
      Citations: 21     Fields:    Translation:AnimalsCells
    32. Gliko O, Brownell WE, Saggau P. Fast two-dimensional standing-wave total-internal-reflection fluorescence microscopy using acousto-optic deflectors. Opt Lett. 2009 Mar 15; 34(6):836-8. PMID: 19282949.
      Citations: 1     Fields:    
    33. Rajagopalan L, Pereira FA, Lichtarge O, Brownell WE. Identification of functionally important residues/domains in membrane proteins using an evolutionary approach coupled with systematic mutational analysis. Methods Mol Biol. 2009; 493:287-97. PMID: 18839354; PMCID: PMC2673147.
      Citations: 5     Fields:    Translation:Cells
    34. Sfondouris J, Rajagopalan L, Pereira FA, Brownell WE. Membrane composition modulates prestin-associated charge movement. J Biol Chem. 2008 Aug 15; 283(33):22473-81. PMID: 18567583; PMCID: PMC2504877.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    35. Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA. Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane. J Biomech Eng. 2008 Jun; 130(3):031007. PMID: 18532856.
      Citations: 5     Fields:    Translation:Cells
    36. Brownell WE. Poking versus deflection: anisotropy in action. Biophys J. 2008 Jun; 94(11):4157-8. PMID: 18310236; PMCID: PMC2480671.
      Citations:    Fields:    Translation:HumansAnimalsCells
    37. Rajagopalan L, Greeson JN, Xia A, Liu H, Sturm A, Raphael RM, Davidson AL, Oghalai JS, Pereira FA, Brownell WE. Tuning of the outer hair cell motor by membrane cholesterol. J Biol Chem. 2007 Dec 14; 282(50):36659-70. PMID: 17933870; PMCID: PMC2679373.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    38. Liao Z, Feng S, Popel AS, Brownell WE, Spector AA. Outer hair cell active force generation in the cochlear environment. J Acoust Soc Am. 2007 Oct; 122(4):2215-25. PMID: 17902857.
      Citations: 8     Fields:    Translation:HumansCells
    39. Zhang R, Qian F, Rajagopalan L, Pereira FA, Brownell WE, Anvari B. Prestin modulates mechanics and electromechanical force of the plasma membrane. Biophys J. 2007 Jul 01; 93(1):L07-9. PMID: 17468166; PMCID: PMC1914414.
      Citations: 14     Fields:    Translation:HumansCells
    40. Zhi M, Ratnanather JT, Ceyhan E, Popel AS, Brownell WE. Hypotonic swelling of salicylate-treated cochlear outer hair cells. Hear Res. 2007 Jun; 228(1-2):95-104. PMID: 17400411; PMCID: PMC2041888.
      Citations: 11     Fields:    Translation:AnimalsCells
    41. Sturm AK, Rajagopalan L, Yoo D, Brownell WE, Pereira FA. Functional expression and microdomain localization of prestin in cultured cells. Otolaryngol Head Neck Surg. 2007 Mar; 136(3):434-9. PMID: 17321873; PMCID: PMC2679365.
      Citations: 21     Fields:    Translation:HumansCells
    42. Anvari B, Zhang R, Qian F, Rajagopalan L, Pereira FA, Brownell WE. Effects of prestin on membrane mechanics and electromechanics. Annu Int Conf IEEE Eng Med Biol Soc. 2007; 2007:5384-6. PMID: 18003225.
      Citations: 3     Fields:    Translation:HumansCells
    43. Rajagopalan L, Patel N, Madabushi S, Goddard JA, Anjan V, Lin F, Shope C, Farrell B, Lichtarge O, Davidson AL, Brownell WE, Pereira FA. Essential helix interactions in the anion transporter domain of prestin revealed by evolutionary trace analysis. J Neurosci. 2006 Dec 06; 26(49):12727-34. PMID: 17151276; PMCID: PMC2675645.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    44. Gliko O, Reddy GD, Anvari B, Brownell WE, Saggau P. Standing wave total internal reflection fluorescence microscopy to measure the size of nanostructures in living cells. J Biomed Opt. 2006 Nov-Dec; 11(6):064013. PMID: 17212536.
      Citations: 6     Fields:    Translation:Cells
    45. Evans MB, Tonini R, Shope CD, Oghalai JS, Jerger JF, Insull W, Brownell WE. Dyslipidemia and auditory function. Otol Neurotol. 2006 Aug; 27(5):609-14. PMID: 16868509; PMCID: PMC3607507.
      Citations: 29     Fields:    Translation:HumansAnimals
    46. Farrell B, Do Shope C, Brownell WE. Voltage-dependent capacitance of human embryonic kidney cells. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Apr; 73(4 Pt 1):041930. PMID: 16711859; PMCID: PMC2778024.
      Citations: 27     Fields:    Translation:HumansCells
    47. Nakagawa T, Oghalai JS, Saggau P, Rabbitt RD, Brownell WE. Photometric recording of transmembrane potential in outer hair cells. J Neural Eng. 2006 Jun; 3(2):79-86. PMID: 16705263; PMCID: PMC2716392.
      Citations: 8     Fields:    Translation:AnimalsCells
    48. de Monvel JB, Brownell WE, Ulfendahl M. Lateral diffusion anisotropy and membrane lipid/skeleton interaction in outer hair cells. Biophys J. 2006 Jul 01; 91(1):364-81. PMID: 16603502; PMCID: PMC1479061.
      Citations: 20     Fields:    Translation:AnimalsCells
    49. Ermilov SA, Murdock DR, Qian F, Brownell WE, Anvari B. Studies of plasma membrane mechanics and plasma membrane-cytoskeleton interactions using optical tweezers and fluorescence imaging. J Biomech. 2007; 40(2):476-80. PMID: 16500663.
      Citations: 6     Fields:    Translation:HumansCells
    50. Liao Z, Popel AS, Brownell WE, Spector AA. High-frequency force generation in the constrained cochlear outer hair cell: a model study. J Assoc Res Otolaryngol. 2005 Dec; 6(4):378-89. PMID: 16237583; PMCID: PMC2504621.
      Citations: 1     Fields:    Translation:HumansCells
    51. Liao Z, Popel AS, Brownell WE, Spector AA. Effect of voltage-dependent membrane properties on active force generation in cochlear outer hair cell. J Acoust Soc Am. 2005 Dec; 118(6):3737-46. PMID: 16419818.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    52. Miller JH, Nawarathna D, Warmflash D, Pereira FA, Brownell WE. Dielectric properties of yeast cells expressed with the motor protein prestin. J Biol Phys. 2005 Dec; 31(3-4):465-75. PMID: 23345911; PMCID: PMC3456335.
      Citations: 1     Fields:    
    53. Murdock DR, Ermilov SA, Spector AA, Popel AS, Brownell WE, Anvari B. Effects of chlorpromazine on mechanical properties of the outer hair cell plasma membrane. Biophys J. 2005 Dec; 89(6):4090-5. PMID: 16199506; PMCID: PMC1366974.
      Citations: 10     Fields:    Translation:AnimalsCells
    54. Spector AA, Popel AS, Eatock RA, Brownell WE. Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response. Ann Biomed Eng. 2005 Aug; 33(8):991-1002. PMID: 16133908.
      Citations: 4     Fields:    Translation:AnimalsCells
    55. Ermilov SA, Murdock DR, El-Daye D, Brownell WE, Anvari B. Effects of salicylate on plasma membrane mechanics. J Neurophysiol. 2005 Sep; 94(3):2105-10. PMID: 15958599.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    56. Liao Z, Popel AS, Brownell WE, Spector AA. Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment. J Acoust Soc Am. 2005 Apr; 117(4 Pt 1):2147-57. PMID: 15898656.
      Citations: 4     Fields:    Translation:HumansCells
    57. Anvari B, Qian F, Pereira F, Brownell W. High frequency electrically-induced force generation by cellular plasma membranes. Conf Proc IEEE Eng Med Biol Soc. 2005; 2006:1055-7. PMID: 17282369.
      Citations:    Fields:    
    58. Rabbitt RD, Ayliffe HE, Christensen D, Pamarthy K, Durney C, Clifford S, Brownell WE. Evidence of piezoelectric resonance in isolated outer hair cells. Biophys J. 2005 Mar; 88(3):2257-65. PMID: 15613632; PMCID: PMC1305275.
      Citations: 14     Fields:    Translation:AnimalsCells
    59. Qian F, Ermilov S, Murdock D, Brownell WE, Anvari B. Combining optical tweezers and patch clamp for studies of cell membrane electromechanics. Rev Sci Instrum. 2004 Sep; 75(9):2937-2942. PMID: 21412445; PMCID: PMC3056459.
      Citations: 14     Fields:    
    60. Weitzel EK, Tasker R, Brownell WE. Outer hair cell piezoelectricity: frequency response enhancement and resonance behavior. J Acoust Soc Am. 2003 Sep; 114(3):1462-6. PMID: 14514199; PMCID: PMC2828812.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    61. Spector AA, Brownell WE, Popel AS. Effect of outer hair cell piezoelectricity on high-frequency receptor potentials. J Acoust Soc Am. 2003 Jan; 113(1):453-61. PMID: 12558282.
      Citations: 27     Fields:    Translation:HumansCells
    62. Morimoto N, Raphael RM, Nygren A, Brownell WE. Excess plasma membrane and effects of ionic amphipaths on mechanics of outer hair cell lateral wall. Am J Physiol Cell Physiol. 2002 May; 282(5):C1076-86. PMID: 11940523.
      Citations: 18     Fields:    Translation:AnimalsCells
    63. Li Z, Anvari B, Takashima M, Brecht P, Torres JH, Brownell WE. Membrane tether formation from outer hair cells with optical tweezers. Biophys J. 2002 Mar; 82(3):1386-95. PMID: 11867454; PMCID: PMC1301940.
      Citations: 47     Fields:    Translation:AnimalsCells
    64. Lue AJ, Zhao HB, Brownell WE. Chlorpromazine alters outer hair cell electromotility. Otolaryngol Head Neck Surg. 2001 Jul; 125(1):71-6. PMID: 11458218.
      Citations: 13     Fields:    Translation:AnimalsCells
    65. Brownell WE, Spector AA, Raphael RM, Popel AS. Micro- and nanomechanics of the cochlear outer hair cell. Annu Rev Biomed Eng. 2001; 3:169-94. PMID: 11447061.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    66. Liu M, Pereira FA, Price SD, Chu MJ, Shope C, Himes D, Eatock RA, Brownell WE, Lysakowski A, Tsai MJ. Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. Genes Dev. 2000 Nov 15; 14(22):2839-54. PMID: 11090132; PMCID: PMC317056.
      Citations: 107     Fields:    Translation:AnimalsCells
    67. Kakehata S, Dallos P, Brownell WE, Iwasa KH, Kachar B, Kalinec F, Ikeda K, Takasaka T. Current concept of outer hair cell motility. Auris Nasus Larynx. 2000 Oct; 27(4):349-55. PMID: 10996495.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    68. Raphael RM, Popel AS, Brownell WE. A membrane bending model of outer hair cell electromotility. Biophys J. 2000 Jun; 78(6):2844-62. PMID: 10827967; PMCID: PMC1300872.
      Citations: 38     Fields:    Translation:AnimalsCells
    69. Ratnanather JT, Popel AS, Brownell WE. An analysis of the hydraulic conductivity of the extracisternal space of the cochlear outer hair cell. J Math Biol. 2000 Apr; 40(4):372-82. PMID: 10853798.
      Citations: 4     Fields:    Translation:HumansCells
    70. Oghalai JS, Zhao HB, Kutz JW, Brownell WE. Voltage- and tension-dependent lipid mobility in the outer hair cell plasma membrane. Science. 2000 Jan 28; 287(5453):658-61. PMID: 10650000; PMCID: PMC1976274.
      Citations: 38     Fields:    Translation:AnimalsCells
    71. Oghalai JS, Holt JR, Nakagawa T, Jung TM, Coker NJ, Jenkins HA, Eatock RA, Brownell WE. Harvesting human hair cells. Ann Otol Rhinol Laryngol. 2000 Jan; 109(1):9-16. PMID: 10651405.
      Citations: 5     Fields:    Translation:HumansCells
    72. Lue AJ, Brownell WE. Salicylate induced changes in outer hair cell lateral wall stiffness. Hear Res. 1999 Sep; 135(1-2):163-8. PMID: 10491964.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    73. Oghalai JS, Tran TD, Raphael RM, Nakagawa T, Brownell WE. Transverse and lateral mobility in outer hair cell lateral wall membranes. Hear Res. 1999 Sep; 135(1-2):19-28. PMID: 10491950.
      Citations: 16     Fields:    Translation:AnimalsCells
    74. Spector AA, Brownell WE, Popel AS. Nonlinear active force generation by cochlear outer hair cell. J Acoust Soc Am. 1999 Apr; 105(4):2414-20. PMID: 10212422.
      Citations: 9     Fields:    Translation:HumansCells
    75. Spector AA, Brownell WE, Popel AS. Mechanical and electromotile characteristics of auditory outer hair cells. Med Biol Eng Comput. 1999 Mar; 37(2):247-51. PMID: 10396830.
      Citations: 4     Fields:    Translation:HumansCells
    76. Chen AY, Brownell WE. Effect of temperature on lateral wall mechanics of the guinea pig outer hair cell. Otolaryngol Head Neck Surg. 1999 Jan; 120(1):46-50. PMID: 9914548.
      Citations:    Fields:    Translation:AnimalsCells
    77. Nguyen TV, Brownell WE. Contribution of membrane cholesterol to outer hair cell lateral wall stiffness. Otolaryngol Head Neck Surg. 1998 Jul; 119(1):14-20. PMID: 9674509.
      Citations: 35     Fields:    Translation:AnimalsCells
    78. Oghalai JS, Holt JR, Nakagawa T, Jung TM, Coker NJ, Jenkins HA, Eatock RA, Brownell WE. Ionic currents and electromotility in inner ear hair cells from humans. J Neurophysiol. 1998 Apr; 79(4):2235-9. PMID: 9535985.
      Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
    79. Spector AA, Brownell WE, Popel AS. Analysis of the micropipet experiment with the anisotropic outer hair cell wall. J Acoust Soc Am. 1998 Feb; 103(2):1001-6. PMID: 9479753.
      Citations: 4     Fields:    Translation:HumansCells
    80. Spector AA, Brownell WE, Popel AS. Estimation of elastic moduli and bending stiffness of the anisotropic outer hair cell wall. J Acoust Soc Am. 1998 Feb; 103(2):1007-11. PMID: 9479754.
      Citations: 11     Fields:    Translation:HumansCells
    81. Oghalai JS, Patel AA, Nakagawa T, Brownell WE. Fluorescence-imaged microdeformation of the outer hair cell lateral wall. J Neurosci. 1998 Jan 01; 18(1):48-58. PMID: 9412485; PMCID: PMC6793406.
      Citations: 37     Fields:    Translation:AnimalsCells
    82. Spector AA, Brownell WE, Popel AS. Elastic properties of the composite outer hair cell wall. Ann Biomed Eng. 1998 Jan-Feb; 26(1):157-65. PMID: 10355560.
      Citations: 7     Fields:    Translation:HumansCells
    83. Halter JA, Kruger RP, Yium MJ, Brownell WE. The influence of the subsurface cisterna on the electrical properties of the outer hair cell. Neuroreport. 1997 Jul 28; 8(11):2517-21. PMID: 9261819.
      Citations: 14     Fields:    Translation:AnimalsCells
    84. Sit PS, Spector AA, Lue AJ, Popel AS, Brownell WE. Micropipette aspiration on the outer hair cell lateral wall. Biophys J. 1997 Jun; 72(6):2812-9. PMID: 9168055; PMCID: PMC1184477.
      Citations: 14     Fields:    Translation:AnimalsCells
    85. Brownell WE. HOW THE EAR WORKS - NATURE'S SOLUTIONS FOR LISTENING. Volta Rev. 1997; 99(5):9-28. PMID: 20585407; PMCID: PMC2888317.
      Citations: 5     
    86. Jerry RA, Popel AS, Brownell WE. Potential distribution for a spheroidal cell having a conductive membrane in an electric field. IEEE Trans Biomed Eng. 1996 Sep; 43(9):970-2. PMID: 9214813.
      Citations: 6     Fields:    Translation:Cells
    87. Ratnanather JT, Zhi M, Brownell WE, Popel AS. Measurements and a model of the outer hair cell hydraulic conductivity. Hear Res. 1996 Jul; 96(1-2):33-40. PMID: 8817304.
      Citations: 8     Fields:    Translation:AnimalsCells
    88. Spector AA, Brownell WE, Popel AS. A model for cochlear outer hair cell deformations in micropipette aspiration experiments: an analytical solution. Ann Biomed Eng. 1996 Jul-Aug; 24(4):241-9. PMID: 8841728.
      Citations: 2     Fields:    Translation:AnimalsCells
    89. Ratnanather JT, Zhi M, Brownell WE, Popel AS. The ratio of elastic moduli of cochlear outer hair cells derived from osmotic experiments. J Acoust Soc Am. 1996 Feb; 99(2):1025-8. PMID: 8609285.
      Citations: 10     Fields:    Translation:AnimalsCells
    90. Chu S, Brownell WE, Montrose MH. Quantitative confocal imaging along the crypt-to-surface axis of colonic crypts. Am J Physiol. 1995 Dec; 269(6 Pt 1):C1557-64. PMID: 8572186.
      Citations: 6     Fields:    Translation:AnimalsCells
    91. Jerry RA, Popel AS, Brownell WE. Outer hair cell length changes in an external electric field. II. The role of electrokinetic forces on the cell surface. J Acoust Soc Am. 1995 Oct; 98(4):2011-7. PMID: 7593923.
      Citations:    Fields:    Translation:HumansCells
    92. Jerry RA, Popel AS, Brownell WE. Outer hair cell length changes in an external electric field. I. The role of intracellular electro-osmotically generated pressure gradients. J Acoust Soc Am. 1995 Oct; 98(4):2000-10. PMID: 7593922.
      Citations: 2     Fields:    Translation:HumansCells
    93. Hu HY, Brownell WE, Bertrand D, Witt CM. Physiologically silent sodium channels in mammalian outer hair cells. J Neurophysiol. 1994 Aug; 72(2):1037-40. PMID: 7983511.
      Citations: 7     Fields:    Translation:AnimalsCells
    94. Chertoff ME, Brownell WE. Characterization of cochlear outer hair cell turgor. Am J Physiol. 1994 Feb; 266(2 Pt 1):C467-79. PMID: 8141262.
      Citations: 20     Fields:    Translation:AnimalsCells
    95. Pollice PA, Brownell WE. Characterization of the outer hair cell's lateral wall membranes. Hear Res. 1993 Nov; 70(2):187-96. PMID: 8294263.
      Citations: 11     Fields:    Translation:AnimalsCells
    96. Clerici WJ, Chertoff ME, Brownell WE, Fechter LD. In vitro organotin administration alters guinea pig cochlear outer hair cell shape and viability. Toxicol Appl Pharmacol. 1993 Jun; 120(2):193-202. PMID: 8511788.
      Citations: 1     Fields:    Translation:AnimalsCells
    97. Zidanic M, Brownell WE. Fine structure of the intracochlear potential field. II. Tone-evoked waveforms and cochlear microphonics. J Neurophysiol. 1992 Jan; 67(1):108-24. PMID: 1552313.
      Citations: 5     Fields:    Translation:Animals
    98. Dieler R, Shehata-Dieler WE, Brownell WE. Concomitant salicylate-induced alterations of outer hair cell subsurface cisternae and electromotility. J Neurocytol. 1991 Aug; 20(8):637-53. PMID: 1940979.
      Citations: 28     Fields:    Translation:AnimalsCells
    99. Shehata WE, Brownell WE, Dieler R. Effects of salicylate on shape, electromotility and membrane characteristics of isolated outer hair cells from guinea pig cochlea. Acta Otolaryngol. 1991; 111(4):707-18. PMID: 1950533.
      Citations: 57     Fields:    Translation:AnimalsCells
    100. Salzer SJ, Mattox DE, Brownell WE. Cochlear damage and increased threshold in alpha-difluoromethylornithine (DFMO) treated guinea pigs. Hear Res. 1990 Jun; 46(1-2):101-12. PMID: 2116404.
      Citations: 3     Fields:    Translation:AnimalsCells
    101. Zidanic M, Brownell WE. Fine structure of the intracochlear potential field. I. The silent current. Biophys J. 1990 Jun; 57(6):1253-68. PMID: 2393707; PMCID: PMC1280835.
      Citations: 47     Fields:    Translation:AnimalsCells
    102. Spirou GA, Brownell WE, Zidanic M. Recordings from cat trapezoid body and HRP labeling of globular bushy cell axons. J Neurophysiol. 1990 May; 63(5):1169-90. PMID: 2358868.
      Citations: 71     Fields:    Translation:AnimalsCells
    103. Brownell WE. Outer hair cell electromotility and otoacoustic emissions. Ear Hear. 1990 Apr; 11(2):82-92. PMID: 2187727; PMCID: PMC2796234.
      Citations: 108     Fields:    Translation:AnimalsCells
    104. Jansen C, Mattox DE, Miller KD, Brownell WE. An animal model of hearing loss from alpha-difluoromethylornithine. Arch Otolaryngol Head Neck Surg. 1989 Oct; 115(10):1234-7. PMID: 2506912.
      Citations: 4     Fields:    Translation:AnimalsCells
    105. Gil-Loyzaga P, Brownell WE. Wheat germ agglutinin and Helix pomatia agglutinin lectin binding on cochlear hair cells. Hear Res. 1988 Jul 15; 34(2):149-55. PMID: 3170357.
      Citations: 3     Fields:    Translation:AnimalsCells
    106. Kachar B, Brownell WE, Altschuler R, Fex J. Electrokinetic shape changes of cochlear outer hair cells. Nature. 1986 Jul 24-30; 322(6077):365-8. PMID: 3736662.
      Citations: 108     Fields:    Translation:AnimalsCells
    107. Siegel JH, Brownell WE. Synaptic and Golgi membrane recycling in cochlear hair cells. J Neurocytol. 1986 Jun; 15(3):311-28. PMID: 3746347.
      Citations: 24     Fields:    Translation:AnimalsCells
    108. Brownell WE, Bader CR, Bertrand D, de Ribaupierre Y. Evoked mechanical responses of isolated cochlear outer hair cells. Science. 1985 Jan 11; 227(4683):194-6. PMID: 3966153.
      Citations: 508     Fields:    Translation:AnimalsCells
    109. Brownell WE. Microscopic observation of cochlear hair cell motility. Scan Electron Microsc. 1984; (Pt 3):1401-6. PMID: 6505622.
      Citations: 16     Fields:    Translation:AnimalsCells
    110. Manis PB, Brownell WE. Synaptic organization of eighth nerve afferents to cat dorsal cochlear nucleus. J Neurophysiol. 1983 Nov; 50(5):1156-81. PMID: 6644365.
      Citations: 7     Fields:    Translation:AnimalsCells
    111. Brownell WE, Manis PB, Zidanic M, Spirou GA. Acoustically evoked radial current densities in scala tympani. J Acoust Soc Am. 1983 Sep; 74(3):792-800. PMID: 6630736.
      Citations: 5     Fields:    Translation:Animals
    112. Brownell WE. Cochlear transduction: an integrative model and review. Hear Res. 1982 Apr; 6(3):335-60. PMID: 6282796; PMCID: PMC2774767.
      Citations: 8     Fields:    Translation:AnimalsCells
    113. Siegel JH, Brownell WE. Presynaptic bodies in outer hair cells of the chinchilla organ of Corti. Brain Res. 1981 Sep 07; 220(1):188-93. PMID: 7272751.
      Citations: 5     Fields:    Translation:AnimalsCells
    114. Brownell WE, Fleshman JW, Karlan MS. Inner and outer hair cells, differential uptake of horseradish peroxidase: a preliminary report. Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 1977 Mar-Apr; 84(2):414-7. PMID: 898511.
      Citations: 1     Translation:AnimalsCells
    115. Young ED, Brownell WE. Responses to tones and noise of single cells in dorsal cochlear nucleus of unanesthetized cats. J Neurophysiol. 1976 Mar; 39(2):282-300. PMID: 1255224.
      Citations: 88     Fields:    Translation:AnimalsPHPublic Health
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