"Pancreatic Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
| Descriptor ID |
D010191
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| MeSH Number(s) |
D06.472.699.587.700 D12.644.400.600 D12.644.548.586.700 D12.776.631.650.600
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pancreatic Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Polypeptide".
This graph shows the total number of publications written about "Pancreatic Polypeptide" by people in this website by year, and whether "Pancreatic Polypeptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreatic Polypeptide" by people in Profiles.
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A Reduced Pancreatic Polypeptide Response is Associated With New-onset Pancreatogenic Diabetes Versus Type 2 Diabetes. J Clin Endocrinol Metab. 2023 04 13; 108(5):e120-e128.
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Paracrine signaling in islet function and survival. J Mol Med (Berl). 2020 04; 98(4):451-467.
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Pancreatic polypeptide administration reduces insulin requirements of artificial pancreas in pancreatectomized dogs. Artif Organs. 2005 Jan; 29(1):83-7.
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Carcinoid tumors of the extrahepatic bile ducts: a study of seven cases. Am J Surg Pathol. 2000 Nov; 24(11):1501-10.
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Pancreatic metaplasia in Barrett's esophagus. An immunohistochemical study. Am J Surg Pathol. 1995 Oct; 19(10):1172-80.
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An unusual skin rash associated with a pancreatic polypeptide-producing tumor of the pancreas. Ann Intern Med. 1988 Jan; 108(1):64-5.
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Absence of hepatic extraction of pancreatic polypeptide in conscious dogs. Am J Physiol. 1983 Oct; 245(4):E401-9.
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Endocrine pancreatic response of children with onset of insulin-requiring diabetes before age 3 and after age 5. J Pediatr. 1982 Jul; 101(1):36-9.