"Pancreatic Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
| Descriptor ID |
D010191
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| MeSH Number(s) |
D06.472.699.587.700 D12.644.400.600 D12.644.548.586.700 D12.776.631.650.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pancreatic Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Polypeptide".
This graph shows the total number of publications written about "Pancreatic Polypeptide" by people in this website by year, and whether "Pancreatic Polypeptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreatic Polypeptide" by people in Profiles.
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A Reduced Pancreatic Polypeptide Response is Associated With New-onset Pancreatogenic Diabetes Versus Type 2 Diabetes. J Clin Endocrinol Metab. 2023 04 13; 108(5):e120-e128.
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Paracrine signaling in islet function and survival. J Mol Med (Berl). 2020 04; 98(4):451-467.
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Metabolic hormones and breast cancer risk among Mexican American Women in the Mano a Mano Cohort Study. Sci Rep. 2019 07 10; 9(1):9989.
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The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis. Am J Physiol Endocrinol Metab. 2019 03 01; 316(3):E397-E409.
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Highly Proliferative a-Cell-Related Islet Endocrine Cells in Human Pancreata. Diabetes. 2018 04; 67(4):674-686.
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Utility of chromogranin A, pancreatic polypeptide, glucagon and gastrin in the diagnosis and follow-up of pancreatic neuroendocrine tumours in multiple endocrine neoplasia type 1 patients. Clin Endocrinol (Oxf). 2016 09; 85(3):400-7.
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Very slow turnover of beta-cells in aged adult mice. Diabetes. 2005 Sep; 54(9):2557-67.
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Pancreatic polypeptide administration reduces insulin requirements of artificial pancreas in pancreatectomized dogs. Artif Organs. 2005 Jan; 29(1):83-7.
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Endocrine pancreas in insulin receptor-deficient mouse pups. Diabetes. 2001 Feb; 50 Suppl 1:S146-9.
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Carcinoid tumors of the extrahepatic bile ducts: a study of seven cases. Am J Surg Pathol. 2000 Nov; 24(11):1501-10.