"Proglucagon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES; and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific yielding numerous bioactive peptides.
| Descriptor ID |
D052336
|
| MeSH Number(s) |
D06.472.317.469 D06.472.699.587.469 D12.644.548.586.469 D12.776.811.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Proglucagon".
Below are MeSH descriptors whose meaning is more specific than "Proglucagon".
This graph shows the total number of publications written about "Proglucagon" by people in this website by year, and whether "Proglucagon" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proglucagon" by people in Profiles.
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SERUM GLP-2 is Increased in Association with Excess Gestational Weight Gain. Am J Perinatol. 2023 03; 40(4):400-406.
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Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity. Mol Metab. 2017 11; 6(11):1350-1359.
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Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake. Domest Anim Endocrinol. 2010 Oct; 39(3):181-93.
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Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells. J Biol Chem. 2003 Jan 10; 278(2):1380-7.