"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
| Descriptor ID |
D001647
|
| MeSH Number(s) |
D04.210.500.105
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".
Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".
This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 3 | 3 |
| 1998 | 3 | 0 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 1 | 4 |
| 2001 | 3 | 0 | 3 |
| 2002 | 3 | 0 | 3 |
| 2003 | 6 | 1 | 7 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 2 | 4 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 4 | 1 | 5 |
| 2010 | 5 | 2 | 7 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 5 | 1 | 6 |
| 2014 | 1 | 3 | 4 |
| 2015 | 6 | 1 | 7 |
| 2016 | 3 | 3 | 6 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 7 | 1 | 8 |
| 2020 | 5 | 2 | 7 |
| 2021 | 6 | 2 | 8 |
| 2022 | 6 | 5 | 11 |
| 2023 | 1 | 7 | 8 |
| 2024 | 3 | 3 | 6 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.
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Phase I trial comparing bile acid and short-chain fatty acid alterations in stool collected from human subjects treated with omadacycline or vancomycin. Antimicrob Agents Chemother. 2025 Feb 13; 69(2):e0125124.
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Clostridioides difficile colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an in vitro model. mSphere. 2025 Feb 25; 10(2):e0104924.
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Homozygous variants in WDR83OS lead to a neurodevelopmental disorder with hypercholanemia. Am J Hum Genet. 2024 Nov 07; 111(11):2566-2581.
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Serum levels of total bile acids are associated with an increased risk of HCC in patients with cirrhosis. Hepatol Commun. 2024 Nov 01; 8(11).
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Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition. J Virol. 2024 Jul 23; 98(7):e0202023.
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The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids. Diabetes. 2024 May 01; 73(5):701-712.
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Structure of orthoreovirus RNA chaperone sNS, a component of viral replication factories. Nat Commun. 2024 Mar 19; 15(1):2460.
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Immunopathogenesis of Primary Biliary Cholangitis, Primary Sclerosing Cholangitis and Autoimmune Hepatitis: Themes and Concepts. Gastroenterology. 2024 06; 166(6):995-1019.
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Repurposing dried blood spot device technology to examine bile acid profiles in human dried fecal spot samples. Am J Physiol Gastrointest Liver Physiol. 2024 02 01; 326(2):G95-G106.
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Prevalence of cerebrotendinous xanthomatosis among patients diagnosed with early-onset idiopathic bilateral cataracts: final analysis. J AAPOS. 2023 08; 27(4):208-211.