Microsatellite Instability
"Microsatellite Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
Descriptor ID |
D053842
|
MeSH Number(s) |
C23.550.362.590 G05.365.590.335.590 G05.370.590
|
Concept/Terms |
Replication Error Phenotype- Replication Error Phenotype
- Error Phenotype, Replication
- Error Phenotypes, Replication
- Phenotype, Replication Error
- Phenotypes, Replication Error
- Replication Error Phenotypes
|
Below are MeSH descriptors whose meaning is more general than "Microsatellite Instability".
Below are MeSH descriptors whose meaning is more specific than "Microsatellite Instability".
This graph shows the total number of publications written about "Microsatellite Instability" by people in this website by year, and whether "Microsatellite Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2007 | 0 | 3 | 3 |
2008 | 1 | 2 | 3 |
2009 | 3 | 4 | 7 |
2010 | 4 | 2 | 6 |
2011 | 6 | 2 | 8 |
2012 | 2 | 3 | 5 |
2013 | 3 | 6 | 9 |
2014 | 2 | 7 | 9 |
2015 | 1 | 4 | 5 |
2016 | 1 | 6 | 7 |
2017 | 5 | 7 | 12 |
2018 | 3 | 12 | 15 |
2019 | 8 | 6 | 14 |
2020 | 1 | 12 | 13 |
2021 | 6 | 9 | 15 |
2022 | 3 | 13 | 16 |
2023 | 3 | 12 | 15 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microsatellite Instability" by people in Profiles.
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Efficacy of immune checkpoint inhibitors for metastatic colorectal cancer with microsatellite instability in second or latter line using synthetic control arms: A non-randomised evaluation. Eur J Cancer. 2024 Mar; 199:113537.
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Immunotherapy in mismatch repair-deficient metastatic colorectal cancer - Outcome and novel predictive markers. Eur J Cancer. 2024 Feb; 198:113495.
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Obesity is associated with improved progression-free survival in Microsatellite-Instability-High endometrial cancer treated with pembrolizumab. Gynecol Oncol. 2024 Jan; 180:139-145.
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Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination. Cancer Res Commun. 2023 12 11; 3(12):2510-2517.
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Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors. Cell. 2023 12 07; 186(25):5620-5637.e16.
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Conditional Overall Survival After Diagnosis of Non-Metastatic Colon Cancer: Impact of Laterality, MSI, and KRAS Status. Ann Surg Oncol. 2024 Jan; 31(1):142-151.
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Endoscopic and imaging outcomes of PD-1 therapy in localised dMMR colorectal cancer. Eur J Cancer. 2023 11; 194:113356.
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BRAF V600E/RAS Mutations and Lynch Syndrome in Patients With MSI-H/dMMR Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors. Oncologist. 2023 09 07; 28(9):771-779.
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Tumor-Agnostic Precision Medicine from the AACR GENIE Database: Clinical Implications. Clin Cancer Res. 2023 08 01; 29(15):2753-2760.
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Tumor-agnostic drug development in dMMR/MSI-H solid tumors. Trends Cancer. 2023 10; 9(10):828-839.