"Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
| Descriptor ID |
D009154
|
| MeSH Number(s) |
G05.365.590
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mutation".
Below are MeSH descriptors whose meaning is more specific than "Mutation".
This graph shows the total number of publications written about "Mutation" by people in this website by year, and whether "Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 25 | 47 | 72 |
| 1996 | 35 | 44 | 79 |
| 1997 | 33 | 56 | 89 |
| 1998 | 39 | 69 | 108 |
| 1999 | 38 | 102 | 140 |
| 2000 | 34 | 100 | 134 |
| 2001 | 37 | 98 | 135 |
| 2002 | 47 | 125 | 172 |
| 2003 | 47 | 146 | 193 |
| 2004 | 54 | 141 | 195 |
| 2005 | 56 | 164 | 220 |
| 2006 | 59 | 178 | 237 |
| 2007 | 83 | 172 | 255 |
| 2008 | 74 | 165 | 239 |
| 2009 | 77 | 168 | 245 |
| 2010 | 63 | 174 | 237 |
| 2011 | 100 | 187 | 287 |
| 2012 | 95 | 175 | 270 |
| 2013 | 88 | 208 | 296 |
| 2014 | 141 | 200 | 341 |
| 2015 | 137 | 222 | 359 |
| 2016 | 160 | 219 | 379 |
| 2017 | 128 | 277 | 405 |
| 2018 | 138 | 245 | 383 |
| 2019 | 126 | 248 | 374 |
| 2020 | 73 | 287 | 360 |
| 2021 | 90 | 248 | 338 |
| 2022 | 3 | 268 | 271 |
| 2023 | 2 | 229 | 231 |
| 2024 | 85 | 168 | 253 |
| 2025 | 1 | 5 | 6 |
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Below are the most recent publications written about "Mutation" by people in Profiles.
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Utilizing Patient-Derived Xenografts to Model Precision Oncology for Biliary Tract Cancer. Clin Cancer Res. 2025 Jan 17; 31(2):387-402.
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Discontiguous recurrences of IDH-wildtype glioblastoma share a common origin with the initial tumor and are frequently hypermutated. Acta Neuropathol Commun. 2025 Jan 16; 13(1):9.
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Frontal lobe intra-axial schwannoma harboring a CHD7::VGLL3 fusion and heterozygous TSC2 p.F1510del mutation in a young child. Mol Biol Rep. 2025 Jan 10; 52(1):112.
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Nav1.2 channel mutations preventing fast inactivation lead to SCN2A encephalopathy. Brain. 2025 Jan 07; 148(1):212-226.
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Molecular Profiling of Biliary Tract Cancers in African American and Caucasian Patients. JCO Precis Oncol. 2025 Jan; 9:e2400712.
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An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup. Sci Transl Med. 2025 Jan; 17(779):eadr2012.
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PARP inhibition radiosensitizes BRCA1 wildtype and mutated breast cancer to proton therapy. Sci Rep. 2024 12 28; 14(1):30897.
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Microsatellite instability and high tumor mutational burden detected by next generation sequencing are concordant with loss of mismatch repair proteins by immunohistochemistry. Cancer Genet. 2025 Jan; 290-291:44-50.
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Phase II Study of Sunitinib in Tumors With c-KIT Mutations: Results From the NCI MATCH ECOG-ACRIN Trial (EAY131) Subprotocol V. JCO Precis Oncol. 2024 Dec; 8:e2400514.
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Metabolic reprogramming by mutant GNAS creates an actionable dependency in intraductal papillary mucinous neoplasms of the pancreas. Gut. 2024 Dec 10; 74(1):75-88.