"Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
| Descriptor ID |
D009154
|
| MeSH Number(s) |
G05.365.590
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mutation".
Below are MeSH descriptors whose meaning is more specific than "Mutation".
This graph shows the total number of publications written about "Mutation" by people in this website by year, and whether "Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 14 | 18 | 32 |
| 1997 | 16 | 35 | 51 |
| 1998 | 23 | 23 | 46 |
| 1999 | 21 | 50 | 71 |
| 2000 | 19 | 53 | 72 |
| 2001 | 20 | 47 | 67 |
| 2002 | 22 | 63 | 85 |
| 2003 | 32 | 69 | 101 |
| 2004 | 31 | 67 | 98 |
| 2005 | 30 | 85 | 115 |
| 2006 | 25 | 78 | 103 |
| 2007 | 38 | 80 | 118 |
| 2008 | 36 | 65 | 101 |
| 2009 | 36 | 69 | 105 |
| 2010 | 27 | 74 | 101 |
| 2011 | 37 | 96 | 133 |
| 2012 | 40 | 85 | 125 |
| 2013 | 37 | 102 | 139 |
| 2014 | 69 | 109 | 178 |
| 2015 | 75 | 116 | 191 |
| 2016 | 78 | 100 | 178 |
| 2017 | 76 | 138 | 214 |
| 2018 | 74 | 137 | 211 |
| 2019 | 62 | 127 | 189 |
| 2020 | 45 | 165 | 210 |
| 2021 | 42 | 134 | 176 |
| 2022 | 4 | 124 | 128 |
| 2023 | 3 | 99 | 102 |
| 2024 | 27 | 81 | 108 |
| 2025 | 19 | 83 | 102 |
| 2026 | 2 | 5 | 7 |
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Below are the most recent publications written about "Mutation" by people in Profiles.
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POD24 is a novel determinant of prognosis in patients with Waldenstr?m macroglobulinemia. Blood Adv. 2026 Apr 14; 10(7):2322-2327.
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Important role in transcription start site selection for the RNA polymerase II-TFIIE-TFIIH interface in Saccharomyces cerevisiae. Genetics. 2026 Apr 04; 232(4).
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Defective DNA Damage Response Is a Targetable Therapeutic Vulnerability in ESR1-Mutant Breast Cancer. Cancer Res. 2026 Apr 02; 86(7):1707-1723.
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Kv4.2V404M Mutation Induces Epileptiform Activity and Multiple Behavioral Abnormalities in Heterozygous Knock-in Mice. J Neurosci. 2026 02 11; 46(6).
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Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth. Mol Cancer Ther. 2026 Feb 04; 25(2):257-271.
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EGFR inhibitor-resistant lung cancers exhibit collateral sensitivity to a covalent, cysteine-independent KEAP1 oligomerizing molecular bridge. Nat Commun. 2026 Jan 14; 17(1):1726.
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Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies. J Med Chem. 2026 Jan 22; 69(2):1119-1134.
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Mutational analysis of human norovirus VP2 elucidates critical molecular interactions for virus assembly. J Virol. 2026 02 17; 100(2):e0142025.
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Therapeutic p63 isoform switching rescues epidermal defects in AEC syndrome. Mol Ther. 2026 Apr 01; 34(4):2324-2342.
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Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1-Related Tumor Predisposition Syndrome. Pediatr Blood Cancer. 2026 Feb; 73(2):e70068.