"Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
| Descriptor ID |
D009154
|
| MeSH Number(s) |
G05.365.590
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mutation".
Below are MeSH descriptors whose meaning is more specific than "Mutation".
This graph shows the total number of publications written about "Mutation" by people in this website by year, and whether "Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 25 | 39 | 64 |
| 1995 | 25 | 47 | 72 |
| 1996 | 35 | 45 | 80 |
| 1997 | 33 | 58 | 91 |
| 1998 | 39 | 73 | 112 |
| 1999 | 38 | 103 | 141 |
| 2000 | 35 | 102 | 137 |
| 2001 | 39 | 100 | 139 |
| 2002 | 47 | 129 | 176 |
| 2003 | 46 | 150 | 196 |
| 2004 | 54 | 142 | 196 |
| 2005 | 56 | 167 | 223 |
| 2006 | 59 | 179 | 238 |
| 2007 | 84 | 173 | 257 |
| 2008 | 74 | 165 | 239 |
| 2009 | 79 | 168 | 247 |
| 2010 | 63 | 176 | 239 |
| 2011 | 100 | 187 | 287 |
| 2012 | 96 | 177 | 273 |
| 2013 | 90 | 206 | 296 |
| 2014 | 142 | 201 | 343 |
| 2015 | 139 | 221 | 360 |
| 2016 | 159 | 218 | 377 |
| 2017 | 126 | 278 | 404 |
| 2018 | 139 | 247 | 386 |
| 2019 | 126 | 249 | 375 |
| 2020 | 73 | 284 | 357 |
| 2021 | 90 | 250 | 340 |
| 2022 | 3 | 265 | 268 |
| 2023 | 2 | 230 | 232 |
| 2024 | 72 | 147 | 219 |
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Below are the most recent publications written about "Mutation" by people in Profiles.
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Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer. Clin Cancer Res. 2024 Nov 15; 30(22):5166-5179.
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Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
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Integrative immunophenotypic and genetic characterization of acute myeloid leukemia with CBFB rearrangement. Am J Clin Pathol. 2024 Nov 04; 162(5):455-463.
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Outcomes and genetic dynamics of acute myeloid leukemia at first relapse. Haematologica. 2024 Nov 01; 109(11):3543-3556.
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Clinical and Genomic Features of Classical and Basal Transcriptional Subtypes in Pancreatic Cancer. Clin Cancer Res. 2024 Nov 01; 30(21):4932-4942.
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Mechanisms of Response and Tolerance to Active RAS Inhibition in KRAS-Mutant Non-Small Cell Lung Cancer. Cancer Discov. 2024 Nov 01; 14(11):2183-2208.
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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer. Cancer Discov. 2024 Nov 01; 14(11):2135-2161.
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MLL oncoprotein levels influence leukemia lineage identities. Nat Commun. 2024 Oct 29; 15(1):9341.
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Homozygous variants in WDR83OS lead to a neurodevelopmental disorder with hypercholanemia. Am J Hum Genet. 2024 Nov 07; 111(11):2566-2581.
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Whole-exome profiles of inflammatory breast cancer and pathological response to neoadjuvant chemotherapy. J Transl Med. 2024 Oct 27; 22(1):969.