"Allelic Imbalance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A situation where one member (allele) of a gene pair is lost (LOSS OF HETEROZYGOSITY) or amplified.
| Descriptor ID |
D022981
|
| MeSH Number(s) |
G05.365.590.029
|
| Concept/Terms |
Allelic Imbalance- Allelic Imbalance
- Allelic Imbalances
- Imbalance, Allelic
- Imbalances, Allelic
|
Below are MeSH descriptors whose meaning is more general than "Allelic Imbalance".
Below are MeSH descriptors whose meaning is more specific than "Allelic Imbalance".
This graph shows the total number of publications written about "Allelic Imbalance" by people in this website by year, and whether "Allelic Imbalance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2016 | 3 | 1 | 4 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Allelic Imbalance" by people in Profiles.
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Impact of homologous recombination status and responses with veliparib combined with first-line chemotherapy in ovarian cancer in the Phase 3 VELIA/GOG-3005 study. Gynecol Oncol. 2022 02; 164(2):245-253.
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Large-scale analysis of acquired chromosomal alterations in non-tumor samples from patients with cancer. Nat Biotechnol. 2020 01; 38(1):90-96.
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Directional allelic imbalance profiling and visualization from multi-sample data with RECUR. Bioinformatics. 2019 07 01; 35(13):2300-2302.
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Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung. EBioMedicine. 2019 Apr; 42:296-303.
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Allele-specific epigenome maps reveal sequence-dependent stochastic switching at regulatory loci. Science. 2018 09 28; 361(6409).
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. Am J Hum Genet. 2016 Jul 07; 99(1):8-21.
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Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq. Bioinformatics. 2016 10 01; 32(19):3015-7.
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Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway. Cancer Res. 2016 07 01; 76(13):3676-83.
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Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer. Clin Cancer Res. 2016 08 01; 22(15):3764-73.
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Natural variation of gene models in Drosophila melanogaster. BMC Genomics. 2015 Mar 17; 16:198.