"DNA Repeat Expansion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increase number of repeats of a genomic, tandemly repeated DNA sequence from one generation to the next.
| Descriptor ID |
D042622
|
| MeSH Number(s) |
G02.111.570.080.708.800.140 G05.360.080.708.800.074 G05.360.340.024.189.220 G05.360.340.024.850.140 G05.365.590.220 G05.558.220
|
| Concept/Terms |
DNA Repeat Expansion- DNA Repeat Expansion
- DNA Repeat Expansions
- Expansion, DNA Repeat
- Expansions, DNA Repeat
- Repeat Expansion, DNA
- Repeat Expansions, DNA
Expanded DNA Repeats- Expanded DNA Repeats
- DNA Repeat, Expanded
- DNA Repeats, Expanded
- Expanded DNA Repeat
- Repeat, Expanded DNA
- Repeats, Expanded DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Repeat Expansion".
Below are MeSH descriptors whose meaning is more specific than "DNA Repeat Expansion".
This graph shows the total number of publications written about "DNA Repeat Expansion" by people in this website by year, and whether "DNA Repeat Expansion" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2005 | 3 | 0 | 3 |
| 2007 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 3 | 5 |
| 2021 | 2 | 1 | 3 |
| 2022 | 1 | 2 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Repeat Expansion" by people in Profiles.
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Disrupted endoplasmic reticulum-mediated autophagosomal biogenesis in a Drosophila model of C9-ALS-FTD. Autophagy. 2024 01; 20(1):94-113.
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Recurrent repeat expansions in human cancer genomes. Nature. 2023 01; 613(7942):96-102.
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Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD. Cell Rep. 2022 09 20; 40(12):111379.
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Defective axonal transport of endo-lysosomes and dense core vesicles in a Drosophila model of C9-ALS/FTD. Traffic. 2022 09; 23(9):430-441.
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C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Sci Adv. 2021 04; 7(15).
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UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. Cell Rep. 2021 03 30; 34(13):108925.
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p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. 2021 02 04; 184(3):689-708.e20.
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Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. Acta Neuropathol. 2020 02; 139(2):407-410.
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New Roles for Canonical Transcription Factors in Repeat Expansion Diseases. Trends Genet. 2020 02; 36(2):81-92.
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C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport. Sci Rep. 2019 10 31; 9(1):15728.