"Genomic Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
| Descriptor ID |
D042822
|
| MeSH Number(s) |
C23.550.362 G05.365.590.335 G05.370
|
| Concept/Terms |
Genomic Instability- Genomic Instability
- Genomic Instabilities
- Instabilities, Genomic
- Instability, Genomic
- Genome Instability
- Genome Instabilities
- Instabilities, Genome
- Instability, Genome
Genomic Stability- Genomic Stability
- Genomic Stabilities
- Stabilities, Genomic
- Stability, Genomic
- Genome Stability
- Genome Stabilities
- Stabilities, Genome
- Stability, Genome
|
Below are MeSH descriptors whose meaning is more general than "Genomic Instability".
Below are MeSH descriptors whose meaning is more specific than "Genomic Instability".
This graph shows the total number of publications written about "Genomic Instability" by people in this website by year, and whether "Genomic Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 5 | 3 | 8 |
| 2006 | 0 | 3 | 3 |
| 2007 | 2 | 3 | 5 |
| 2008 | 2 | 5 | 7 |
| 2009 | 2 | 4 | 6 |
| 2010 | 1 | 4 | 5 |
| 2011 | 1 | 3 | 4 |
| 2012 | 3 | 5 | 8 |
| 2013 | 4 | 3 | 7 |
| 2014 | 3 | 5 | 8 |
| 2015 | 3 | 7 | 10 |
| 2016 | 1 | 4 | 5 |
| 2017 | 1 | 5 | 6 |
| 2018 | 6 | 1 | 7 |
| 2019 | 1 | 5 | 6 |
| 2020 | 2 | 3 | 5 |
| 2021 | 2 | 6 | 8 |
| 2022 | 1 | 3 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 2 | 3 | 5 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Genomic Instability" by people in Profiles.
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DNA replication initiation timing is important for maintaining genome integrity. J Bacteriol. 2025 Aug 21; 207(8):e0017525.
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Deficits in mitochondrial dynamics and iron balance result in templated insertions. Nat Commun. 2025 Jul 01; 16(1):5454.
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Clues to transcription/replication collision-induced DNA damage: it was RNAP, in the chromosome, with the fork. FEBS Lett. 2025 Jan; 599(2):209-243.
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Update on Recommendations for Cancer Screening and Surveillance in Children with Genomic Instability Disorders. Clin Cancer Res. 2024 Nov 15; 30(22):5009-5020.
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Yeast EndoG prevents genome instability by degrading extranuclear DNA species. Nat Commun. 2024 09 03; 15(1):7653.
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GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer. Nat Commun. 2024 Mar 08; 15(1):2132.
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Role of chromosomal cohesion and separation in aneuploidy and tumorigenesis. Cell Mol Life Sci. 2024 Feb 22; 81(1):100.
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Genomic features reveal potential benefit of adding anti-PD-1 immunotherapy to treat non-upper aerodigestive tract natural killer/T-cell lymphoma. Leukemia. 2024 04; 38(4):829-839.
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Stepwise requirements for polymerases d and ? in theta-mediated end joining. Nature. 2023 11; 623(7988):836-841.
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Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration. Cell. 2023 09 28; 186(20):4404-4421.e20.