"Genomic Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.
| Descriptor ID |
D042822
|
| MeSH Number(s) |
C23.550.362 G05.365.590.335 G05.370
|
| Concept/Terms |
Genomic Instability- Genomic Instability
- Genomic Instabilities
- Instabilities, Genomic
- Instability, Genomic
- Genome Instability
- Genome Instabilities
- Instabilities, Genome
- Instability, Genome
Genomic Stability- Genomic Stability
- Genomic Stabilities
- Stabilities, Genomic
- Stability, Genomic
- Genome Stability
- Genome Stabilities
- Stabilities, Genome
- Stability, Genome
|
Below are MeSH descriptors whose meaning is more general than "Genomic Instability".
Below are MeSH descriptors whose meaning is more specific than "Genomic Instability".
This graph shows the total number of publications written about "Genomic Instability" by people in this website by year, and whether "Genomic Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 |
| 2004 | 6 | 3 | 9 |
| 2005 | 10 | 4 | 14 |
| 2006 | 6 | 8 | 14 |
| 2007 | 6 | 8 | 14 |
| 2008 | 6 | 10 | 16 |
| 2009 | 13 | 12 | 25 |
| 2010 | 7 | 9 | 16 |
| 2011 | 6 | 8 | 14 |
| 2012 | 8 | 14 | 22 |
| 2013 | 12 | 6 | 18 |
| 2014 | 5 | 11 | 16 |
| 2015 | 4 | 11 | 15 |
| 2016 | 2 | 7 | 9 |
| 2017 | 6 | 13 | 19 |
| 2018 | 8 | 4 | 12 |
| 2019 | 1 | 7 | 8 |
| 2020 | 3 | 5 | 8 |
| 2021 | 5 | 11 | 16 |
| 2022 | 1 | 6 | 7 |
| 2023 | 0 | 5 | 5 |
| 2024 | 2 | 2 | 4 |
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Below are the most recent publications written about "Genomic Instability" by people in Profiles.
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Update on Recommendations for Cancer Screening and Surveillance in Children with Genomic Instability Disorders. Clin Cancer Res. 2024 Nov 15; 30(22):5009-5020.
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Yeast EndoG prevents genome instability by degrading extranuclear DNA species. Nat Commun. 2024 Sep 03; 15(1):7653.
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GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer. Nat Commun. 2024 Mar 08; 15(1):2132.
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Role of chromosomal cohesion and separation in aneuploidy and tumorigenesis. Cell Mol Life Sci. 2024 Feb 22; 81(1):100.
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Stepwise requirements for polymerases d and ? in theta-mediated end joining. Nature. 2023 Nov; 623(7988):836-841.
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Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration. Cell. 2023 09 28; 186(20):4404-4421.e20.
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SETD2 safeguards the genome against isochromosome formation. Proc Natl Acad Sci U S A. 2023 09 26; 120(39):e2303752120.
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Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes. Breast Cancer Res Treat. 2023 Nov; 202(1):191-201.
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Implications of Translesion DNA Synthesis Polymerases on Genomic Stability and Human Health. Mol Cell Biol. 2023; 43(8):401-425.
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Low-molecular-weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer. Oncogene. 2022 Dec; 41(50):5331-5346.