"Codon, Nonsense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
| Descriptor ID |
D018389
|
| MeSH Number(s) |
D13.444.735.544.355.250.235 G05.360.335.355.250.235 G05.365.590.195
|
| Concept/Terms |
Codon, Nonsense- Codon, Nonsense
- Premature Termination Codon
- Codon, Premature Termination
- Codons, Premature Termination
- Premature Termination Codons
- Termination Codon, Premature
- Termination Codons, Premature
- Premature Stop Codon
- Codon, Premature Stop
- Codons, Premature Stop
- Premature Stop Codons
- Stop Codon, Premature
- Stop Codons, Premature
- Nonsense Codon
- Codons, Nonsense
- Nonsense Codons
- Codon, Termination, Premature
Mutation, Nonsense- Mutation, Nonsense
- Mutations, Nonsense
- Nonsense Mutations
- Nonsense Mutation
Ochre Nonsense Codon- Ochre Nonsense Codon
- Codon, Ochre Nonsense
- Codons, Ochre Nonsense
- Nonsense Codon, Ochre
- Nonsense Codons, Ochre
- Ochre Nonsense Codons
Ochre Nonsense Mutation- Ochre Nonsense Mutation
- Mutation, Ochre Nonsense
- Mutations, Ochre Nonsense
- Nonsense Mutation, Ochre
- Nonsense Mutations, Ochre
- Ochre Nonsense Mutations
Amber Nonsense Mutation- Amber Nonsense Mutation
- Amber Nonsense Mutations
- Mutation, Amber Nonsense
- Mutations, Amber Nonsense
- Nonsense Mutation, Amber
- Nonsense Mutations, Amber
Opal Nonsense Mutation- Opal Nonsense Mutation
- Mutation, Opal Nonsense
- Mutations, Opal Nonsense
- Nonsense Mutation, Opal
- Nonsense Mutations, Opal
- Opal Nonsense Mutations
Amber Nonsense Codon- Amber Nonsense Codon
- Amber Nonsense Codons
- Codon, Amber Nonsense
- Codons, Amber Nonsense
- Nonsense Codons, Amber
- Nonsense Codon, Amber
Codon, Unassigned- Codon, Unassigned
- Codons, Unassigned
- Unassigned Codons
- Unassigned Codon
Opal Nonsense Codon- Opal Nonsense Codon
- Codon, Opal Nonsense
- Codons, Opal Nonsense
- Nonsense Codon, Opal
- Nonsense Codons, Opal
- Opal Nonsense Codons
|
Below are MeSH descriptors whose meaning is more general than "Codon, Nonsense".
Below are MeSH descriptors whose meaning is more specific than "Codon, Nonsense".
This graph shows the total number of publications written about "Codon, Nonsense" by people in this website by year, and whether "Codon, Nonsense" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 3 | 4 |
| 2005 | 2 | 2 | 4 |
| 2006 | 4 | 0 | 4 |
| 2007 | 2 | 3 | 5 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 5 | 5 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 3 | 2 | 5 |
| 2015 | 3 | 3 | 6 |
| 2016 | 1 | 3 | 4 |
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 3 | 5 |
| 2019 | 2 | 4 | 6 |
| 2020 | 1 | 5 | 6 |
| 2021 | 2 | 4 | 6 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Codon, Nonsense" by people in Profiles.
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Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes. Oncotarget. 2022; 13:756-767.
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Naked (N) mutant mice carry a nonsense mutation in the homeobox of Hoxc13. Exp Dermatol. 2022 03; 31(3):330-340.
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Selection for or against escape from nonsense mediated decay is a novel signature for the detection of cancer genes. Cancer Genet. 2021 11; 258-259:80-84.
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Impact of Genotype, Serum Bile Acids, and Surgical Biliary Diversion on Native Liver Survival in FIC1 Deficiency. Hepatology. 2021 08; 74(2):892-906.
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Expanding the clinical phenotype in patients with disease causing variants associated with atypical Usher syndrome. Ophthalmic Genet. 2021 12; 42(6):664-673.
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Perturbations of genes essential for M?llerian duct and W?lffian duct development in Mayer-Rokitansky-K?ster-Hauser syndrome. Am J Hum Genet. 2021 02 04; 108(2):337-345.
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Absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy in folliculin-interacting protein 1 deficiency. Blood. 2021 01 28; 137(4):493-499.
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FBXO28 causes developmental and epileptic encephalopathy with profound intellectual disability. Epilepsia. 2021 01; 62(1):e13-e21.
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MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons. J Neurosci. 2020 11 04; 40(45):8746-8766.
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Human NK cell deficiency as a result of biallelic mutations in MCM10. J Clin Invest. 2020 10 01; 130(10):5272-5286.