"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Descriptor ID |
D012333
|
MeSH Number(s) |
D13.444.735.544
|
Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 18 | 99 | 117 |
1995 | 15 | 86 | 101 |
1996 | 21 | 105 | 126 |
1997 | 16 | 104 | 120 |
1998 | 14 | 98 | 112 |
1999 | 14 | 121 | 135 |
2000 | 9 | 178 | 187 |
2001 | 11 | 162 | 173 |
2002 | 12 | 182 | 194 |
2003 | 8 | 189 | 197 |
2004 | 15 | 185 | 200 |
2005 | 17 | 189 | 206 |
2006 | 15 | 161 | 176 |
2007 | 12 | 137 | 149 |
2008 | 17 | 147 | 164 |
2009 | 13 | 140 | 153 |
2010 | 9 | 154 | 163 |
2011 | 10 | 130 | 140 |
2012 | 17 | 125 | 142 |
2013 | 18 | 122 | 140 |
2014 | 21 | 93 | 114 |
2015 | 19 | 88 | 107 |
2016 | 13 | 62 | 75 |
2017 | 14 | 58 | 72 |
2018 | 11 | 44 | 55 |
2019 | 13 | 35 | 48 |
2020 | 7 | 29 | 36 |
2021 | 6 | 32 | 38 |
2022 | 0 | 54 | 54 |
2023 | 0 | 37 | 37 |
2024 | 3 | 22 | 25 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2024 Nov 15; 210(10):1219-1229.
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SARS-CoV-2 XBB.1.5 mRNA booster vaccination elicits limited mucosal immunity. Sci Transl Med. 2024 Oct 23; 16(770):eadp8920.
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Deciphering Transcriptomic Variations in Hematopoietic Lineages: HSCs, EBs, and MKs. Int J Mol Sci. 2024 Sep 19; 25(18).
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Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity. J Control Release. 2024 Oct; 374:550-562.
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RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 Sep 05; 84(17):3192-3208.e11.
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RNA sequestration in P-bodies sustains myeloid leukaemia. Nat Cell Biol. 2024 Oct; 26(10):1745-1758.
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The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis and maintain translational repression of maternal mRNA and oocyte quality. Mol Biol Cell. 2024 Oct 01; 35(10):ar131.
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Comparison of uridine and N1-methylpseudouridine mRNA platforms in development of an Andes virus vaccine. Nat Commun. 2024 Jul 30; 15(1):6421.
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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer. Nature. 2024 Aug; 632(8025):656-663.
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HuR controls glutaminase RNA metabolism. Nat Commun. 2024 Jul 04; 15(1):5620.