"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Descriptor ID |
D012333
|
MeSH Number(s) |
D13.444.735.544
|
Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 9 | 33 | 42 |
1996 | 13 | 45 | 58 |
1997 | 5 | 32 | 37 |
1998 | 7 | 40 | 47 |
1999 | 8 | 48 | 56 |
2000 | 6 | 75 | 81 |
2001 | 6 | 63 | 69 |
2002 | 2 | 86 | 88 |
2003 | 1 | 91 | 92 |
2004 | 9 | 85 | 94 |
2005 | 6 | 88 | 94 |
2006 | 9 | 88 | 97 |
2007 | 4 | 59 | 63 |
2008 | 11 | 73 | 84 |
2009 | 8 | 60 | 68 |
2010 | 5 | 76 | 81 |
2011 | 7 | 56 | 63 |
2012 | 7 | 56 | 63 |
2013 | 6 | 62 | 68 |
2014 | 13 | 45 | 58 |
2015 | 13 | 51 | 64 |
2016 | 9 | 39 | 48 |
2017 | 8 | 39 | 47 |
2018 | 7 | 28 | 35 |
2019 | 10 | 20 | 30 |
2020 | 3 | 24 | 27 |
2021 | 3 | 25 | 28 |
2022 | 0 | 39 | 39 |
2023 | 0 | 32 | 32 |
2024 | 2 | 18 | 20 |
2025 | 2 | 3 | 5 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Recent advances in RNA-based therapeutics for neurodevelopmental disorders. Curr Opin Genet Dev. 2025 Jun; 92:102339.
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Protocol for unlocking alternative polyadenylation insights from bulk RNA-seq data with PolyAMiner-Bulk. STAR Protoc. 2025 Mar 21; 6(1):103664.
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A novel method for semi-quantitative detection of HPV16 and HPV18 mRNA with a low-cost, open-source fluorimeter. Anal Bioanal Chem. 2025 Apr; 417(9):1765-1778.
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Familial chylomicronemia syndrome and treatments to target hepatic APOC3 mRNA. Atherosclerosis. 2025 Apr; 403:119114.
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Alternative polyadenylation shapes the molecular and clinical features of lung adenocarcinoma. Hum Mol Genet. 2025 Jan 23; 34(1):1-10.
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Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2024 Nov 15; 210(10):1219-1229.
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SARS-CoV-2 XBB.1.5 mRNA booster vaccination elicits limited mucosal immunity. Sci Transl Med. 2024 Oct 23; 16(770):eadp8920.
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Small Molecule Screening Identifies HSP90 as a Modifier of RNA Foci in Myotonic Dystrophy Type 1. Mol Cell Biol. 2025; 45(6):225-237.
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Deciphering Transcriptomic Variations in Hematopoietic Lineages: HSCs, EBs, and MKs. Int J Mol Sci. 2024 Sep 19; 25(18).
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Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity. J Control Release. 2024 Oct; 374:550-562.