"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
|
| MeSH Number(s) |
D13.444.735.544
|
| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 12 | 40 | 52 |
| 1997 | 5 | 30 | 35 |
| 1998 | 6 | 37 | 43 |
| 1999 | 5 | 42 | 47 |
| 2000 | 6 | 75 | 81 |
| 2001 | 5 | 55 | 60 |
| 2002 | 2 | 79 | 81 |
| 2003 | 1 | 86 | 87 |
| 2004 | 9 | 78 | 87 |
| 2005 | 6 | 82 | 88 |
| 2006 | 8 | 85 | 93 |
| 2007 | 4 | 58 | 62 |
| 2008 | 10 | 73 | 83 |
| 2009 | 6 | 62 | 68 |
| 2010 | 4 | 72 | 76 |
| 2011 | 7 | 55 | 62 |
| 2012 | 6 | 49 | 55 |
| 2013 | 6 | 57 | 63 |
| 2014 | 11 | 45 | 56 |
| 2015 | 13 | 52 | 65 |
| 2016 | 7 | 39 | 46 |
| 2017 | 10 | 41 | 51 |
| 2018 | 6 | 27 | 33 |
| 2019 | 9 | 18 | 27 |
| 2020 | 2 | 26 | 28 |
| 2021 | 2 | 28 | 30 |
| 2022 | 0 | 45 | 45 |
| 2023 | 0 | 34 | 34 |
| 2024 | 3 | 19 | 22 |
| 2025 | 7 | 11 | 18 |
| 2026 | 1 | 5 | 6 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Autoregulation of three yeast ribosomal protein genes by splicing inhibition. G3 (Bethesda). 2026 06 03; 16(6).
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Circulating Extracellular Vesicles Suggest Race-Associated Transcriptomic Differences in Preterm Birth: A Pilot Study. Int J Mol Sci. 2026 May 25; 27(11).
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Modulating alternative splicing of MECP2 is a potential therapeutic strategy for Rett syndrome. Sci Transl Med. 2026 Mar 04; 18(839):eadq4529.
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CELF1 is a non-canonical eIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs. Nucleic Acids Res. 2026 Feb 24; 54(5).
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Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics. Br J Biomed Sci. 2026; 83:15687.
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Tumor microenvironment transcriptional activity enables robust stratification of chemotherapy response in triple-negative breast cancer. Cell Rep Med. 2026 Feb 17; 7(2):102610.
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FASTK post-transcriptional regulators - a 'FAST-tracK' in mitochondrial gene expression. Biochem Soc Trans. 2025 10 29; 53(5):1311-1323.
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The IFIT2-IFIT3 antiviral complex targets short 5' untranslated regions on viral mRNAs for translation inhibition. Nat Microbiol. 2025 Nov; 10(11):2934-2948.
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Sperm and offspring production in a nonobstructive azoospermia mouse model via testicular mRNA delivery using lipid nanoparticles. Proc Natl Acad Sci U S A. 2025 Oct 21; 122(42):e2516573122.
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Single-nucleus mRNA-sequencing reveals dynamics of lipogenic and thermogenic adipocyte populations in murine brown adipose tissue in response to cold exposure. Mol Metab. 2025 Nov; 101:102252.