"Riboswitch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Part of a MESSENGER RNA molecule that undergoes a conformation change upon binding a specific metabolite or other small molecule thereby regulating the messenger RNA's transcription, post-transcriptional processing, transport, translation, or stability in response to varying levels of the metabolite or other small molecule.
| Descriptor ID |
D058928
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| MeSH Number(s) |
D13.444.735.544.427 D13.444.735.790.878.942.500 G02.111.570.080.689.687.124 G05.360.080.689.687.124
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Riboswitch".
Below are MeSH descriptors whose meaning is more specific than "Riboswitch".
This graph shows the total number of publications written about "Riboswitch" by people in this website by year, and whether "Riboswitch" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Riboswitch" by people in Profiles.
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Effect of Sequence on the Interactions of Divalent Cations with M-Box Riboswitches from Mycobacterium tuberculosis and Bacillus subtilis. Biochemistry. 2021 09 21; 60(37):2781-2794.
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Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions. Nat Struct Mol Biol. 2019 12; 26(12):1094-1105.
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Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2077-E2085.
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The Biology of Free Guanidine As Revealed by Riboswitches. Biochemistry. 2017 01 17; 56(2):345-347.
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Metabolism of Free Guanidine in Bacteria Is Regulated by a Widespread Riboswitch Class. Mol Cell. 2017 Jan 19; 65(2):220-230.
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Small molecule fluoride toxicity agonists. Chem Biol. 2015 Apr 23; 22(4):527-534.
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An ancient riboswitch class in bacteria regulates purine biosynthesis and one-carbon metabolism. Mol Cell. 2015 Jan 22; 57(2):317-28.
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Methods for using new conceptual tools and parameters to assess RNA structure by small-angle X-ray scattering. Methods Enzymol. 2014; 549:235-63.
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Riboswitches in eubacteria sense the second messenger c-di-AMP. Nat Chem Biol. 2013 Dec; 9(12):834-9.
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Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure. Nucleic Acids Res. 2013 Dec; 41(22):10462-75.