"RNA Caps" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleic acid structures found on the 5' end of eukaryotic cellular and viral messenger RNA and some heterogeneous nuclear RNAs. These structures, which are positively charged, protect the above specified RNAs at their termini against attack by phosphatases and other nucleases and promote mRNA function at the level of initiation of translation. Analogs of the RNA caps (RNA CAP ANALOGS), which lack the positive charge, inhibit the initiation of protein synthesis.
| Descriptor ID |
D012315
|
| MeSH Number(s) |
D03.633.100.759.646.454.700 D13.444.735.544.500 D13.695.667.454.700 D13.695.827.426.700
|
| Concept/Terms |
RNA Caps- RNA Caps
- Caps, RNA
- 5' Capped RNA
- RNA, 5' Capped
- 5' mRNA Cap Structure
|
Below are MeSH descriptors whose meaning is more general than "RNA Caps".
Below are MeSH descriptors whose meaning is more specific than "RNA Caps".
This graph shows the total number of publications written about "RNA Caps" by people in this website by year, and whether "RNA Caps" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Caps" by people in Profiles.
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Generation and Characterization of In Vitro Transcribed mRNA. Methods Mol Biol. 2024; 2786:147-165.
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Enzymatic characterization of mRNA cap adenosine-N6 methyltransferase PCIF1 activity on uncapped RNAs. J Biol Chem. 2022 04; 298(4):101751.
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Dicer cleaves 5'-extended microRNA precursors originating from RNA polymerase II transcription start sites. Nucleic Acids Res. 2018 06 20; 46(11):5737-5752.
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Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors. Mol Cell Proteomics. 2017 04; 16(4 suppl 1):S215-S229.
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MYC Mediates mRNA Cap Methylation of Canonical Wnt/?-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase. Mol Cancer Res. 2017 02; 15(2):213-224.
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Enterovirus Control of Translation and RNA Granule Stress Responses. Viruses. 2016 Mar 30; 8(4):93.
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Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues. Arch Pathol Lab Med. 2011 Mar; 135(3):365-71.
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ZNF9 activation of IRES-mediated translation of the human ODC mRNA is decreased in myotonic dystrophy type 2. PLoS One. 2010 Feb 18; 5(2):e9301.
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Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling. Mol Cell Biol. 2009 Aug; 29(15):4235-49.
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Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt. Mol Cell Biol. 2008 Mar; 28(6):2011-22.