"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
| Descriptor ID |
D006152
|
| MeSH Number(s) |
D03.633.100.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
|
| Concept/Terms |
Cyclic GMP- Cyclic GMP
- GMP, Cyclic
- Guanosine Cyclic Monophosphate
- Cyclic Monophosphate, Guanosine
- Monophosphate, Guanosine Cyclic
- Guanosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Guanosine Cyclic
- Cyclic 3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3',5' Monophosphate
|
Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".
This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 3 | 4 |
| 2005 | 2 | 4 | 6 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 2 | 1 | 3 |
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 1 | 3 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 3 | 4 |
| 2014 | 0 | 2 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 3 | 1 | 4 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 2 | 4 |
| 2020 | 3 | 0 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic GMP" by people in Profiles.
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A divergent cyclic nucleotide binding protein promotes Plasmodium ookinete infection of the mosquito. PLoS Pathog. 2025 Sep; 21(9):e1013467.
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An auto-inhibited state of protein kinase G and implications for selective activation. Elife. 2022 08 05; 11.
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TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022 05; 605(7909):349-356.
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Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells. Gene Ther. 2023 04; 30(3-4):222-231.
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Dynamical Basis of Allosteric Activation for the Plasmodium falciparum Protein Kinase G. J Phys Chem B. 2021 06 24; 125(24):6532-6542.
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Cyclic guanosine monophosphate and 10-year change in left ventricular mass: the Multi-Ethnic Study of Atherosclerosis (MESA). Biomarkers. 2021 Jun; 26(4):309-317.
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Cyclic nucleotide selectivity of protein kinase G isozymes. Protein Sci. 2021 02; 30(2):316-327.
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Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase. J Biol Chem. 2020 06 19; 295(25):8480-8491.
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Cyclic Guanosine Monophosphate and Risk of Incident Heart Failure and Other Cardiovascular Events: the ARIC Study. J Am Heart Assoc. 2020 01 21; 9(2):e013966.
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Associations Between the Cyclic Guanosine Monophosphate Pathway and Cardiovascular Risk Factors: MESA. J Am Heart Assoc. 2019 12 17; 8(24):e013149.