"Guanosine Pentaphosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine 5'-triphosphate 2'(3')-diphosphate. A guanine nucleotide containing five phosphate groups. Three phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot II.
Descriptor ID |
D006158
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MeSH Number(s) |
D03.633.100.759.646.454.440 D13.695.667.454.440 D13.695.827.426.440
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Concept/Terms |
Guanosine Pentaphosphate- Guanosine Pentaphosphate
- Pentaphosphate, Guanosine
- Guanosine 3'-Diphosphate 5'-Triphosphate
- 3'-Diphosphate 5'-Triphosphate, Guanosine
- 5'-Triphosphate, Guanosine 3'-Diphosphate
- Guanosine 3' Diphosphate 5' Triphosphate
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Below are MeSH descriptors whose meaning is more general than "Guanosine Pentaphosphate".
Below are MeSH descriptors whose meaning is more specific than "Guanosine Pentaphosphate".
This graph shows the total number of publications written about "Guanosine Pentaphosphate" by people in this website by year, and whether "Guanosine Pentaphosphate" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanosine Pentaphosphate" by people in Profiles.
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Antibiotic Scars Left on the Gut Microbiota from the Stringent Response. Trends Microbiol. 2018 09; 26(9):735-737.
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Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp. Mol Cell. 2015 Feb 19; 57(4):735-749.
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GTP dysregulation in Bacillus subtilis cells lacking (p)ppGpp results in phenotypic amino acid auxotrophy and failure to adapt to nutrient downshift and regulate biosynthesis genes. J Bacteriol. 2014 Jan; 196(1):189-201.
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Dose-dependent reduction of replication elongation rate by (p)ppGpp in Escherichia coli and Bacillus subtilis. Mol Microbiol. 2013 Apr; 88(1):93-104.
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The transcription factor DksA prevents conflicts between DNA replication and transcription machinery. Cell. 2010 May 14; 141(4):595-605.
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Nutritional control of elongation of DNA replication by (p)ppGpp. Cell. 2007 Mar 09; 128(5):865-75.