"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 2 | 5 | 7 |
| 2007 | 7 | 4 | 11 |
| 2008 | 4 | 6 | 10 |
| 2009 | 8 | 5 | 13 |
| 2010 | 9 | 3 | 12 |
| 2011 | 12 | 8 | 20 |
| 2012 | 7 | 8 | 15 |
| 2013 | 15 | 17 | 32 |
| 2014 | 13 | 14 | 27 |
| 2015 | 19 | 13 | 32 |
| 2016 | 17 | 10 | 27 |
| 2017 | 13 | 19 | 32 |
| 2018 | 9 | 25 | 34 |
| 2019 | 12 | 18 | 30 |
| 2020 | 6 | 18 | 24 |
| 2021 | 15 | 15 | 30 |
| 2022 | 1 | 18 | 19 |
| 2023 | 4 | 17 | 21 |
| 2024 | 11 | 17 | 28 |
| 2025 | 6 | 5 | 11 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Mouse metastable epialleles are extremely rare. Nucleic Acids Res. 2025 Jul 19; 53(14).
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Maternal loss of mouse Nlrp2 alters the transcriptome and DNA methylome in GV oocytes and impairs zygotic genome activation in embryos. Clin Epigenetics. 2025 Jun 03; 17(1):92.
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Epigenetic Aging in Pediatric-Onset Multiple Sclerosis. Neurology. 2025 Jun 24; 104(12):e213673.
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Genetic, Transcriptomic, and Epigenomic Insights into Sj?gren's Disease: An Integrative Network Investigation and Immune Diseases Comparison. Int J Mol Sci. 2025 May 13; 26(10).
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Let-7 restrains an epigenetic circuit in AT2 cells to prevent fibrogenic intermediates in pulmonary fibrosis. Nat Commun. 2025 May 10; 16(1):4353.
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Histone acetylation modulators in breast cancer. Breast Cancer Res. 2025 Mar 31; 27(1):49.
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Mapping the transcriptional and epigenetic landscape of organotypic endothelial diversity in the developing and adult mouse. Nat Cardiovasc Res. 2025 Apr; 4(4):473-495.
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Genetics and Epigenetics of Legg-Calv?-Perthes Disease. JBJS Rev. 2025 Mar 01; 13(3).
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Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells. ACS Synth Biol. 2025 02 21; 14(2):384-397.
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Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium. Clin Epigenetics. 2025 Jan 22; 17(1):12.