"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 5 | 6 | 11 |
| 2006 | 9 | 10 | 19 |
| 2007 | 12 | 10 | 22 |
| 2008 | 15 | 15 | 30 |
| 2009 | 18 | 15 | 33 |
| 2010 | 19 | 11 | 30 |
| 2011 | 19 | 18 | 37 |
| 2012 | 16 | 20 | 36 |
| 2013 | 24 | 35 | 59 |
| 2014 | 25 | 30 | 55 |
| 2015 | 28 | 23 | 51 |
| 2016 | 26 | 25 | 51 |
| 2017 | 21 | 32 | 53 |
| 2018 | 14 | 44 | 58 |
| 2019 | 17 | 30 | 47 |
| 2020 | 14 | 31 | 45 |
| 2021 | 21 | 32 | 53 |
| 2022 | 4 | 33 | 37 |
| 2023 | 3 | 28 | 31 |
| 2024 | 3 | 7 | 10 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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The role of epigenetic mechanisms in the long-term effects of early-life adversity and mother-infant relationship on physiology and behavior of offspring in laboratory rats and mice. Dev Psychobiol. 2024 Apr; 66(3):e22479.
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Neural tube defects and epigenetics: role of histone post-translational histone modifications. Epigenomics. 2024 Mar; 16(6):419-426.
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Tumor- and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes. Cancer Cell. 2024 02 12; 42(2):225-237.e5.
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CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon. JCI Insight. 2024 Jan 23; 9(2).
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Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer Res Commun. 2024 01 19; 4(1):164-169.
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Epigenetic regulation of asymmetric cell division by the LIBR-BRD4 axis. Nucleic Acids Res. 2024 Jan 11; 52(1):154-165.
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Comprehensive evaluation of smoking exposures and their interactions on DNA methylation. EBioMedicine. 2024 Feb; 100:104956.
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A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation. Commun Biol. 2024 01 09; 7(1):66.
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Current and future therapeutic strategies for high-grade gliomas leveraging the interplay between epigenetic regulators and kinase signaling networks. J Exp Clin Cancer Res. 2024 Jan 05; 43(1):12.
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Spatial and Temporal Relationship between Epithelial-Mesenchymal Transition (EMT) and Stem Cells in Cancer. Clin Chem. 2024 01 04; 70(1):190-205.