"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 3 | 5 | 8 |
| 2007 | 7 | 3 | 10 |
| 2008 | 3 | 6 | 9 |
| 2009 | 6 | 5 | 11 |
| 2010 | 9 | 5 | 14 |
| 2011 | 11 | 8 | 19 |
| 2012 | 6 | 8 | 14 |
| 2013 | 17 | 17 | 34 |
| 2014 | 14 | 13 | 27 |
| 2015 | 22 | 13 | 35 |
| 2016 | 18 | 10 | 28 |
| 2017 | 13 | 20 | 33 |
| 2018 | 9 | 27 | 36 |
| 2019 | 14 | 16 | 30 |
| 2020 | 7 | 21 | 28 |
| 2021 | 16 | 16 | 32 |
| 2022 | 2 | 20 | 22 |
| 2023 | 6 | 18 | 24 |
| 2024 | 12 | 18 | 30 |
| 2025 | 18 | 18 | 36 |
| 2026 | 6 | 11 | 17 |
To return to the timeline,
click here.
Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
-
Weaning drives microbiome-mediated epigenetic regulation to shape immune memory in mice. Nat Microbiol. 2026 Apr; 11(4):1064-1079.
-
Rare epigenetic alterations are conserved across hematopoietic differentiation stages after mycobacterial infection. JCI Insight. 2026 01 23; 11(2).
-
Mouse metastable epialleles are extremely rare. Nucleic Acids Res. 2025 Jul 19; 53(14).
-
DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. 2025 Aug 19; 152(7):436-449.
-
Maternal asthma and newborn DNA methylation. Clin Epigenetics. 2025 May 10; 17(1):79.
-
DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations. Clin Epigenetics. 2025 Jan 22; 17(1):11.
-
Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium. Clin Epigenetics. 2025 Jan 22; 17(1):12.
-
A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 11 07; 31(11):1630-1649.e8.
-
TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance. Proc Natl Acad Sci U S A. 2024 10 08; 121(41):e2404841121.
-
CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma. Mol Oncol. 2025 Mar; 19(3):764-784.