"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 5 | 6 | 11 |
| 2006 | 9 | 9 | 18 |
| 2007 | 12 | 10 | 22 |
| 2008 | 15 | 15 | 30 |
| 2009 | 19 | 15 | 34 |
| 2010 | 19 | 11 | 30 |
| 2011 | 20 | 18 | 38 |
| 2012 | 16 | 21 | 37 |
| 2013 | 24 | 34 | 58 |
| 2014 | 24 | 29 | 53 |
| 2015 | 29 | 24 | 53 |
| 2016 | 28 | 26 | 54 |
| 2017 | 21 | 33 | 54 |
| 2018 | 14 | 46 | 60 |
| 2019 | 18 | 32 | 50 |
| 2020 | 13 | 29 | 42 |
| 2021 | 19 | 31 | 50 |
| 2022 | 3 | 30 | 33 |
| 2023 | 6 | 27 | 33 |
| 2024 | 13 | 20 | 33 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Transcriptomic and epigenomic signatures distinguish high- and low-risk endotypes for liver tumor development. Environ Mol Mutagen. 2024 Nov; 65(9):351-359.
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Interplay of Reactive Oxygen Species (ROS) and Epigenetic Remodelling in Cardiovascular Diseases Pathogenesis: A Contemporary Perspective. Front Biosci (Landmark Ed). 2024 Nov 21; 29(11):398.
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Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer. Clin Cancer Res. 2024 Nov 15; 30(22):5166-5179.
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Multiomic and clinical analysis of multiply recurrent meningiomas reveals risk factors, underlying biology, and insights into evolution. Sci Adv. 2024 Oct 25; 10(43):eadn4419.
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A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 Nov 07; 31(11):1630-1649.e8.
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Histone lactylation drives CD8+ T cell metabolism and function. Nat Immunol. 2024 Nov; 25(11):2140-2151.
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TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance. Proc Natl Acad Sci U S A. 2024 Oct 08; 121(41):e2404841121.
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Epigenomic and Transcriptomic Profiling of Solitary Fibrous Tumors Identifies Site-Specific Patterns and Candidate Genes Regulated by DNA Methylation. Lab Invest. 2024 Nov; 104(11):102146.
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BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. Sci Transl Med. 2024 Sep 11; 16(764):eadp0004.
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Intrinsic Epigenetic State of Primary Osteosarcoma Drives Metastasis. Mol Cancer Res. 2024 09 04; 22(9):864-878.