"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 4 | 4 |
| 2002 | 2 | 2 | 4 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 3 | 2 | 5 |
| 2006 | 0 | 7 | 7 |
| 2007 | 5 | 7 | 12 |
| 2008 | 2 | 5 | 7 |
| 2009 | 3 | 4 | 7 |
| 2010 | 5 | 3 | 8 |
| 2011 | 0 | 9 | 9 |
| 2012 | 1 | 5 | 6 |
| 2013 | 1 | 15 | 16 |
| 2014 | 3 | 13 | 16 |
| 2015 | 2 | 9 | 11 |
| 2016 | 0 | 11 | 11 |
| 2017 | 3 | 7 | 10 |
| 2018 | 0 | 12 | 12 |
| 2019 | 3 | 10 | 13 |
| 2020 | 2 | 9 | 11 |
| 2021 | 1 | 8 | 9 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 6 | 6 |
| 2024 | 1 | 4 | 5 |
| 2025 | 0 | 7 | 7 |
| 2026 | 0 | 3 | 3 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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Methylation signatures distinguish non-small cell lung cancer subtypes and are associated with survival in smokers with lung squamous cell carcinoma. J Natl Cancer Inst. 2026 Jul 01; 118(7):1299-1312.
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Global impact of germline structural variation on the cancer proteome. Nat Commun. 2026 Apr 14; 17(1).
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DNA methylation is associated with von Willebrand factor and coagulation factor VIII plasma levels: the atherosclerosis risk in communities study. Clin Epigenetics. 2026 Mar 02; 18(1).
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Epigenome-wide association study meta-analysis of BMI in African Americans. HGG Adv. 2026 Jan 15; 7(1):100552.
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Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy. Nat Commun. 2025 Dec 02; 16(1):10962.
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DNA methylation episignature for Smith-Magenis and Potocki-Lupski syndromes: a mirror perspective. Eur J Hum Genet. 2026 01; 34(1):90-98.
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DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. 2025 Aug 19; 152(7):436-449.
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Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors. Nat Commun. 2025 May 21; 16(1):4713.
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Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nat Commun. 2025 May 20; 16(1):4678.
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Epigenome-wide association study of incident type 2 diabetes in Black and White participants from the Atherosclerosis Risk in Communities Study. Diabetologia. 2025 Apr; 68(4):815-834.