"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 0 | 4 | 4 |
| 2002 | 2 | 2 | 4 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 3 | 2 | 5 |
| 2006 | 0 | 7 | 7 |
| 2007 | 5 | 8 | 13 |
| 2008 | 2 | 6 | 8 |
| 2009 | 4 | 4 | 8 |
| 2010 | 5 | 4 | 9 |
| 2011 | 0 | 9 | 9 |
| 2012 | 1 | 6 | 7 |
| 2013 | 1 | 16 | 17 |
| 2014 | 3 | 13 | 16 |
| 2015 | 2 | 10 | 12 |
| 2016 | 0 | 11 | 11 |
| 2017 | 4 | 6 | 10 |
| 2018 | 0 | 13 | 13 |
| 2019 | 3 | 12 | 15 |
| 2020 | 2 | 9 | 11 |
| 2021 | 1 | 8 | 9 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 7 | 7 |
| 2024 | 1 | 4 | 5 |
| 2025 | 0 | 5 | 5 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. 2025 Aug 19; 152(7):436-449.
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Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors. Nat Commun. 2025 May 21; 16(1):4713.
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Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nat Commun. 2025 May 20; 16(1):4678.
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Epigenome-wide association study of incident type 2 diabetes in Black and White participants from the Atherosclerosis Risk in Communities Study. Diabetologia. 2025 Apr; 68(4):815-834.
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Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium. Clin Epigenetics. 2025 Jan 22; 17(1):12.
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Plasma DNA Methylation-Based Biomarkers for MPNST Detection in Patients With Neurofibromatosis Type 1. Mol Carcinog. 2025 Jan; 64(1):44-56.
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DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations. Nucleic Acids Res. 2024 Oct 28; 52(19):11442-11454.
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The ICF syndrome protein CDCA7 harbors a unique DNA binding domain that recognizes a CpG dyad in the context of a non-B DNA. Sci Adv. 2024 Aug 23; 10(34):eadr0036.
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Exposure-associated DNA methylation among people exposed to multiple industrial pollutants. Clin Epigenetics. 2024 Aug 20; 16(1):111.
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The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.