"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 2 | 2 | 4 |
| 2000 | 4 | 2 | 6 |
| 2001 | 4 | 11 | 15 |
| 2002 | 8 | 6 | 14 |
| 2003 | 4 | 9 | 13 |
| 2004 | 4 | 8 | 12 |
| 2005 | 5 | 6 | 11 |
| 2006 | 2 | 10 | 12 |
| 2007 | 5 | 13 | 18 |
| 2008 | 4 | 11 | 15 |
| 2009 | 8 | 7 | 15 |
| 2010 | 7 | 8 | 15 |
| 2011 | 1 | 19 | 20 |
| 2012 | 2 | 10 | 12 |
| 2013 | 2 | 22 | 24 |
| 2014 | 3 | 23 | 26 |
| 2015 | 3 | 14 | 17 |
| 2016 | 1 | 20 | 21 |
| 2017 | 5 | 9 | 14 |
| 2018 | 0 | 13 | 13 |
| 2019 | 3 | 13 | 16 |
| 2020 | 3 | 11 | 14 |
| 2021 | 0 | 8 | 8 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 6 | 6 |
| 2024 | 4 | 3 | 7 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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Plasma DNA Methylation-Based Biomarkers for MPNST Detection in Patients With Neurofibromatosis Type 1. Mol Carcinog. 2025 Jan; 64(1):44-56.
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DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations. Nucleic Acids Res. 2024 Oct 28; 52(19):11442-11454.
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The ICF syndrome protein CDCA7 harbors a unique DNA binding domain that recognizes a CpG dyad in the context of a non-B DNA. Sci Adv. 2024 Aug 23; 10(34):eadr0036.
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The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
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Systemic interindividual DNA methylation variants in cattle share major hallmarks with those in humans. Genome Biol. 2024 Jul 15; 25(1):185.
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DNA methylation of the Lamin A/C gene is associated with congenital heart disease. Birth Defects Res. 2024 Jul; 116(7):e2381.
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Comprehensive evaluation of smoking exposures and their interactions on DNA methylation. EBioMedicine. 2024 Feb; 100:104956.
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Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls. Cancer. 2024 03 15; 130(6):913-926.
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Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer. Epigenetics. 2023 12; 18(1):2180585.
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Epigenomic signature of major congenital heart defects in newborns with Down syndrome. Hum Genomics. 2023 10 06; 17(1):92.