"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
|
| MeSH Number(s) |
G05.308.203.374
|
| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
|
Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 4 | 2 | 6 |
| 2001 | 6 | 9 | 15 |
| 2002 | 4 | 5 | 9 |
| 2003 | 7 | 15 | 22 |
| 2004 | 8 | 10 | 18 |
| 2005 | 6 | 18 | 24 |
| 2006 | 6 | 11 | 17 |
| 2007 | 7 | 19 | 26 |
| 2008 | 9 | 24 | 33 |
| 2009 | 5 | 17 | 22 |
| 2010 | 4 | 29 | 33 |
| 2011 | 10 | 24 | 34 |
| 2012 | 8 | 26 | 34 |
| 2013 | 5 | 29 | 34 |
| 2014 | 6 | 28 | 34 |
| 2015 | 2 | 13 | 15 |
| 2016 | 2 | 17 | 19 |
| 2017 | 4 | 10 | 14 |
| 2018 | 1 | 11 | 12 |
| 2019 | 1 | 9 | 10 |
| 2020 | 0 | 5 | 5 |
| 2021 | 2 | 6 | 8 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gene Silencing" by people in Profiles.
-
Global miRNA profiling reveals key molecules that contribute to different chronic lymphocytic leukemia incidences in Asian and Western populations. Haematologica. 2024 02 01; 109(2):479-492.
-
Regulation of microRNA expression by the adaptor protein GRB2. Sci Rep. 2023 06 16; 13(1):9784.
-
ASO silencing of a glycosyltransferase, Poglut1 , improves the liver phenotypes in mouse models of Alagille syndrome. Hepatology. 2023 11 01; 78(5):1337-1351.
-
Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation. FEBS J. 2022 01; 289(2):417-435.
-
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin ?1/NF-?B pathway. Cell Cycle. 2021 09; 20(18):1875-1889.
-
Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers. Cell Rep Med. 2021 07 20; 2(7):100349.
-
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases. Neurotherapeutics. 2021 07; 18(3):1710-1728.
-
Interdependencies between Toll-like receptors in Leishmania infection. Immunology. 2021 09; 164(1):173-189.
-
Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood Cancer J. 2021 05 20; 11(5):98.
-
Assessment of In Vivo siRNA Delivery in Cancer Mouse Models. Methods Mol Biol. 2021; 2372:157-168.