"RNA Precursors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA transcripts of the DNA that are in some unfinished stage of post-transcriptional processing (RNA PROCESSING, POST-TRANSCRIPTIONAL) required for function. RNA precursors may undergo several steps of RNA SPLICING during which the phosphodiester bonds at exon-intron boundaries are cleaved and the introns are excised. Consequently a new bond is formed between the ends of the exons. Resulting mature RNAs can then be used; for example, mature mRNA (RNA, MESSENGER) is used as a template for protein production.
Descriptor ID |
D012322
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MeSH Number(s) |
D13.400.730 D13.444.735.640
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Concept/Terms |
RNA Precursor- RNA Precursor
- Precursor, RNA
- Precursor RNA
- RNA, Precursor
Primary RNA Transcript- Primary RNA Transcript
- RNA Transcript, Primary
- Transcript, Primary RNA
- Primary Transcript, RNA
- RNA Primary Transcript
- Transcript, RNA Primary
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Below are MeSH descriptors whose meaning is more general than "RNA Precursors".
Below are MeSH descriptors whose meaning is more specific than "RNA Precursors".
This graph shows the total number of publications written about "RNA Precursors" by people in this website by year, and whether "RNA Precursors" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 0 | 2 | 2 |
1997 | 1 | 2 | 3 |
1998 | 1 | 2 | 3 |
1999 | 1 | 2 | 3 |
2000 | 1 | 1 | 2 |
2001 | 4 | 0 | 4 |
2002 | 1 | 3 | 4 |
2003 | 2 | 1 | 3 |
2004 | 1 | 1 | 2 |
2005 | 3 | 4 | 7 |
2006 | 1 | 2 | 3 |
2007 | 2 | 1 | 3 |
2008 | 1 | 0 | 1 |
2009 | 2 | 1 | 3 |
2010 | 1 | 1 | 2 |
2011 | 0 | 1 | 1 |
2012 | 1 | 3 | 4 |
2013 | 2 | 1 | 3 |
2014 | 1 | 0 | 1 |
2015 | 0 | 4 | 4 |
2016 | 1 | 3 | 4 |
2017 | 2 | 1 | 3 |
2018 | 3 | 1 | 4 |
2019 | 3 | 1 | 4 |
2020 | 0 | 1 | 1 |
2021 | 1 | 1 | 2 |
2022 | 1 | 0 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Precursors" by people in Profiles.
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A deep intronic recurrent CHEK2 variant c.1009-118_1009-87delinsC affects pre-mRNA splicing and contributes to hereditary breast cancer predisposition. Breast. 2024 Jun; 75:103721.
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An Arabidopsis pre-RNA processing8a (prp8a) missense allele restores splicing of a subset of mis-spliced mRNAs. Plant Physiol. 2022 08 01; 189(4):2175-2192.
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Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing. Elife. 2022 06 13; 11.
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Best practices to ensure robust investigation of circular RNAs: pitfalls and tips. EMBO Rep. 2021 03 03; 22(3):e52072.
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RNAi Screening to Identify Factors That Control Circular RNA Localization. Methods Mol Biol. 2021; 2209:321-332.
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Splicing factor SF3B1 promotes endometrial cancer progression via regulating KSR2 RNA maturation. Cell Death Dis. 2020 10 10; 11(10):842.
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Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex. Nat Struct Mol Biol. 2019 09; 26(9):830-839.
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A protein-RNA interaction atlas of the ribosome biogenesis factor AATF. Sci Rep. 2019 07 30; 9(1):11071.
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Nol9 Is a Spatial Regulator for the Human ITS2 Pre-rRNA Endonuclease-Kinase Complex. J Mol Biol. 2019 09 06; 431(19):3771-3786.
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Formation of mammalian preribosomes proceeds from intermediate to composed state during ribosome maturation. J Biol Chem. 2019 07 12; 294(28):10746-10757.