"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.
| Descriptor ID |
D020871
|
| MeSH Number(s) |
G02.111.780
|
| Concept/Terms |
mRNA Degradation- mRNA Degradation
- Degradation, mRNA
- mRNA Transcript Degradation
- Degradation, mRNA Transcript
- Transcript Degradation, mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA Stability".
Below are MeSH descriptors whose meaning is more specific than "RNA Stability".
This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 3 | 4 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 4 | 2 | 6 |
| 2015 | 2 | 3 | 5 |
| 2016 | 2 | 4 | 6 |
| 2017 | 0 | 2 | 2 |
| 2020 | 0 | 5 | 5 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
| 2024 | 2 | 1 | 3 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA Stability" by people in Profiles.
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A non-canonical role for HIF-1a: redirecting DGCR8 to the RNA exosome for snoRNA degradation and translational modulation. Nucleic Acids Res. 2026 Jan 22; 54(3).
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MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer. Cancer Discov. 2024 Sep 04; 14(9):1699-1716.
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Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans. Nucleic Acids Res. 2024 05 22; 52(9):4985-5001.
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Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation. Nucleic Acids Res. 2024 04 12; 52(6):3358-3374.
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Genetic variants associated mRNA stability in lung. BMC Genomics. 2022 Mar 11; 23(1):196.
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Widespread microRNA degradation elements in target mRNAs can assist the encoded proteins. Genes Dev. 2021 12 01; 35(23-24):1595-1609.
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Emerging roles of alternative cleavage and polyadenylation (APA) in human disease. J Cell Physiol. 2022 01; 237(1):149-160.
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Delayed Processing of Secretin-Induced Pancreas Fluid Influences the Quality and Integrity of Proteins and Nucleic Acids. Pancreas. 2021 01 01; 50(1):17-28.
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HEPN RNases - an emerging class of functionally distinct RNA processing and degradation enzymes. Crit Rev Biochem Mol Biol. 2021 02; 56(1):88-108.
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Methylation of HSP70 Orchestrates Its Binding to and Stabilization of BCL2 mRNA and Renders Pancreatic Cancer Cells Resistant to Therapeutics. Cancer Res. 2020 10 15; 80(20):4500-4513.