"Proteostasis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulation of the concentration, folding, interactions, and cellular localization of each of the proteins that comprise the PROTEOME.
| Descriptor ID |
D000074702
|
| MeSH Number(s) |
G02.111.730 G03.816
|
| Concept/Terms |
Proteostasis- Proteostasis
- Proteostases
- Protein Homeostasis
- Homeostases, Protein
- Homeostasis, Protein
- Protein Homeostases
|
Below are MeSH descriptors whose meaning is more general than "Proteostasis".
Below are MeSH descriptors whose meaning is more specific than "Proteostasis".
This graph shows the total number of publications written about "Proteostasis" by people in this website by year, and whether "Proteostasis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 3 | 2 | 5 |
| 2019 | 4 | 1 | 5 |
| 2020 | 3 | 0 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 2 | 1 | 3 |
| 2023 | 2 | 0 | 2 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proteostasis" by people in Profiles.
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Sex-specific proteostasis and urothelial responses to senolytic therapy in the aged mouse bladder. J Gerontol A Biol Sci Med Sci. 2026 03 10; 81(4).
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Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors. Science. 2023 09 08; 381(6662):eabn4180.
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Pharmacological management of disease by overcoming structural adversity. Cell Chem Biol. 2023 01 19; 30(1):1-2.
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Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells. Genes Dev. 2022 08 01; 36(15-16):887-900.
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Restoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload. Cell Death Dis. 2022 04 20; 13(4):381.
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Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome. Eur Respir J. 2022 03; 59(3).
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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance. Nat Commun. 2021 09 06; 12(1):5270.
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Inflammasomes and Proteostasis Novel Molecular Mechanisms Associated With Atrial Fibrillation. Circ Res. 2020 06 19; 127(1):73-90.
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The integrated stress response: From mechanism to disease. Science. 2020 04 24; 368(6489).
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The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020 03 18; 48(5):2621-2642.