"Metabolic Clearance Rate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.
| Descriptor ID |
D008657
|
| MeSH Number(s) |
E01.370.225.843 E05.200.843 G03.490 G07.690.595 G07.690.725.513
|
| Concept/Terms |
Metabolic Clearance Rate- Metabolic Clearance Rate
- Clearance Rate, Metabolic
- Clearance Rates, Metabolic
- Metabolic Clearance Rates
- Rate, Metabolic Clearance
- Rates, Metabolic Clearance
|
Below are MeSH descriptors whose meaning is more general than "Metabolic Clearance Rate".
Below are MeSH descriptors whose meaning is more specific than "Metabolic Clearance Rate".
This graph shows the total number of publications written about "Metabolic Clearance Rate" by people in this website by year, and whether "Metabolic Clearance Rate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 3 | 3 |
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 1 | 7 | 8 |
| 2003 | 0 | 11 | 11 |
| 2004 | 1 | 8 | 9 |
| 2005 | 0 | 9 | 9 |
| 2006 | 0 | 7 | 7 |
| 2007 | 0 | 6 | 6 |
| 2008 | 0 | 7 | 7 |
| 2009 | 1 | 3 | 4 |
| 2010 | 0 | 4 | 4 |
| 2011 | 0 | 5 | 5 |
| 2012 | 0 | 6 | 6 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 4 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Metabolic Clearance Rate" by people in Profiles.
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Longitudinal Impact of Acute Spinal Cord Injury on Clinical Pharmacokinetics of Riluzole, a Potential Neuroprotective Agent. J Clin Pharmacol. 2021 09; 61(9):1232-1242.
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Racial Disparity in Drug Disposition in the Digestive Tract. Int J Mol Sci. 2021 Jan 21; 22(3).
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A Pharmacokinetic Analysis of Hemodialysis for Metformin-Associated Lactic Acidosis. J Med Toxicol. 2021 01; 17(1):70-74.
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Lung clearance index in healthy volunteers, measured using a novel portable system with a closed circuit wash-in. PLoS One. 2020; 15(2):e0229300.
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Differences in the rate of nicotine metabolism among smokers with and without HIV. AIDS. 2019 05 01; 33(6):1083-1088.
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Population pharmacokinetic analysis of vancomycin in pediatric continuous renal replacement therapy. Eur J Clin Pharmacol. 2019 Aug; 75(8):1089-1097.
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Population Pharmacokinetics of Vancomycin in Pediatric Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med. 2018 10; 19(10):973-980.
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Phenobarbital population pharmacokinetics across the pediatric age spectrum. Epilepsia. 2018 07; 59(7):1327-1333.
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A phase 1/2 dose-finding, safety, and activity study of cabazitaxel in pediatric patients with refractory solid tumors including tumors of the central nervous system. Pediatr Blood Cancer. 2018 09; 65(9):e27217.
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Influence of Disease and Patient Characteristics on Daratumumab Exposure and Clinical Outcomes in Relapsed or Refractory Multiple Myeloma. Clin Pharmacokinet. 2018 04; 57(4):529-538.