"Area Under Curve" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)
| Descriptor ID |
D019540
|
| MeSH Number(s) |
E05.318.740.200 G03.787.101 G07.690.725.064 N06.850.520.830.200
|
| Concept/Terms |
Area Under Curve- Area Under Curve
- Area Under Curves
- Curve, Area Under
- Curves, Area Under
- Under Curve, Area
- Under Curves, Area
- AUC
|
Below are MeSH descriptors whose meaning is more general than "Area Under Curve".
Below are MeSH descriptors whose meaning is more specific than "Area Under Curve".
This graph shows the total number of publications written about "Area Under Curve" by people in this website by year, and whether "Area Under Curve" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 7 | 7 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 8 | 8 |
| 2001 | 0 | 9 | 9 |
| 2002 | 0 | 17 | 17 |
| 2003 | 0 | 14 | 14 |
| 2004 | 0 | 23 | 23 |
| 2005 | 0 | 22 | 22 |
| 2006 | 0 | 16 | 16 |
| 2007 | 0 | 15 | 15 |
| 2008 | 0 | 22 | 22 |
| 2009 | 0 | 15 | 15 |
| 2010 | 0 | 26 | 26 |
| 2011 | 0 | 18 | 18 |
| 2012 | 0 | 32 | 32 |
| 2013 | 0 | 22 | 22 |
| 2014 | 0 | 24 | 24 |
| 2015 | 0 | 29 | 29 |
| 2016 | 1 | 21 | 22 |
| 2017 | 1 | 22 | 23 |
| 2018 | 0 | 11 | 11 |
| 2019 | 0 | 12 | 12 |
| 2020 | 0 | 13 | 13 |
| 2021 | 0 | 17 | 17 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 4 | 5 |
| 2024 | 1 | 2 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Area Under Curve" by people in Profiles.
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Evaluation of Vancomycin Dose Needed to Achieve 24-Hour Area Under the Concentration-Time Curve to Minimum Inhibitory Concentration Ratio Greater Than or Equal to 400 Using Pharmacometric Approaches in Pediatric Intensive Care Patients. Crit Care Explor. 2024 Oct 01; 6(10):e1159.
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Early Metabolic Endpoints Identify Persistent Treatment Efficacy in Recent-Onset Type 1 Diabetes Immunotherapy Trials. Diabetes Care. 2024 Jun 01; 47(6):1048-1055.
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A Relative Bioavailability, Bioequivalence, and Food Effect Study of Niraparib Tablets in Patients with Advanced Solid Tumors. Clin Ther. 2024 03; 46(3):228-238.
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Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol. 2023 10 01; 41(28):4453-4454.
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Characterization of Extended-Release Lorazepam: Pharmacokinetic Results Across Phase 1 Clinical Studies. J Clin Psychopharmacol. 2023 Jul-Aug 01; 43(4):350-360.
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Health system-scale language models are all-purpose prediction engines. Nature. 2023 Jul; 619(7969):357-362.
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Machine Learning Models Using Routinely Collected Clinical Data Offer Robust and Interpretable Predictions of 90-Day Unplanned Acute Care Use for Cancer Immunotherapy Patients. JCO Clin Cancer Inform. 2023 03; 7:e2200123.
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Identification of delayed diagnosis of paediatric appendicitis in administrative data: a multicentre retrospective validation study. BMJ Open. 2023 02 28; 13(2):e064852.
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Validation of the new ABC score for predicting 30-day mortality in gastrointestinal bleeding. BMC Gastroenterol. 2022 Jun 21; 22(1):301.
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Using dipstick urinalysis to predict development of acute kidney injury in patients with COVID-19. BMC Nephrol. 2022 02 01; 23(1):50.