"Tissue Distribution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
| Descriptor ID |
D014018
|
| MeSH Number(s) |
G03.787.917 G07.690.725.949
|
| Concept/Terms |
Tissue Distribution- Tissue Distribution
- Distribution, Tissue
- Distributions, Tissue
- Tissue Distributions
|
Below are MeSH descriptors whose meaning is more general than "Tissue Distribution".
Below are MeSH descriptors whose meaning is more specific than "Tissue Distribution".
This graph shows the total number of publications written about "Tissue Distribution" by people in this website by year, and whether "Tissue Distribution" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 7 | 7 |
| 1997 | 0 | 8 | 8 |
| 1998 | 0 | 6 | 6 |
| 1999 | 0 | 14 | 14 |
| 2000 | 0 | 19 | 19 |
| 2001 | 0 | 15 | 15 |
| 2002 | 0 | 23 | 23 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 10 | 10 |
| 2005 | 0 | 12 | 12 |
| 2006 | 0 | 14 | 14 |
| 2007 | 0 | 7 | 7 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 6 | 6 |
| 2010 | 0 | 6 | 6 |
| 2011 | 0 | 5 | 5 |
| 2012 | 0 | 10 | 10 |
| 2013 | 0 | 6 | 6 |
| 2014 | 0 | 5 | 5 |
| 2015 | 0 | 6 | 6 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 5 | 5 |
| 2018 | 0 | 5 | 5 |
| 2019 | 0 | 11 | 11 |
| 2020 | 0 | 9 | 9 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 5 | 5 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tissue Distribution" by people in Profiles.
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A comprehensive atlas of AAV tropism in the mouse. Mol Ther. 2025 Mar 05; 33(3):1282-1299.
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Harnessing RNA Technology to Advance Therapeutic Vaccine Antigens against Chagas Disease. ACS Appl Mater Interfaces. 2024 Apr 03; 16(13):15832-15846.
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A phase I/II study of preoperative letrozole, everolimus, and carotuximab in stage 2 and 3 hormone receptor-positive and Her2-negative breast cancer. Breast Cancer Res Treat. 2023 Apr; 198(2):217-229.
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Pegylated arginine deiminase depletes plasma arginine but maintains tissue arginine availability in young pigs. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E641-E652.
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A prospective study of a simple algorithm to individually dose high-dose methotrexate for children with leukemia at risk for methotrexate toxicities. Cancer Chemother Pharmacol. 2019 02; 83(2):349-360.
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Absorption and Distribution Kinetics of the 13C-Labeled Tomato Carotenoid Phytoene in Healthy Adults. J Nutr. 2016 Feb; 146(2):368-76.
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Characterization of Polymyxin B Biodistribution and Disposition in an Animal Model. Antimicrob Agents Chemother. 2016 Feb; 60(2):1029-34.
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A comparison of plasma and prostate lycopene in response to typical servings of tomato soup, sauce or juice in men before prostatectomy. Br J Nutr. 2015 Aug 28; 114(4):596-607.
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GENE REGULATION. Discrete functions of nuclear receptor Rev-erba couple metabolism to the clock. Science. 2015 Jun 26; 348(6242):1488-92.
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Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer. Phys Biol. 2014 Nov 26; 11(6):065002.