"Dealkylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The removing of alkyl groups from a compound. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
| Descriptor ID |
D003640
|
| MeSH Number(s) |
G02.111.188 G02.607.141 G03.219
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dealkylation".
Below are MeSH descriptors whose meaning is more specific than "Dealkylation".
This graph shows the total number of publications written about "Dealkylation" by people in this website by year, and whether "Dealkylation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dealkylation" by people in Profiles.
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Bedaquiline metabolism: enzymes and novel metabolites. Drug Metab Dispos. 2014 May; 42(5):863-6.
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CPY3A4-mediated a-hydroxyaldehyde formation in saquinavir metabolism. Drug Metab Dispos. 2014 Feb; 42(2):213-20.
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Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice. Drug Metab Dispos. 2010 May; 38(5):871-8.
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Ontogeny of dextromethorphan O- and N-demethylation in the first year of life. Clin Pharmacol Ther. 2007 Apr; 81(4):510-6.
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A method for the determination of amitriptyline and its metabolites nortriptyline, 10-hydroxyamitriptyline, and 10-hydroxynortriptyline in human plasma using stable isotope dilution and gas chromatography-chemical ionization mass spectrometry (GC-CIMS). Clin Pharmacol Ther. 1979 Jun; 25(6):844-56.