"Microsomes, Liver" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.
| Descriptor ID |
D008862
|
| MeSH Number(s) |
A11.284.835.540.541
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Microsomes, Liver".
Below are MeSH descriptors whose meaning is more specific than "Microsomes, Liver".
This graph shows the total number of publications written about "Microsomes, Liver" by people in this website by year, and whether "Microsomes, Liver" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 |
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 4 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 4 | 5 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 3 | 3 |
| 2018 | 0 | 1 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microsomes, Liver" by people in Profiles.
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Characterizing the metabolites of the tyrosine-kinase inhibitor pexidartinib in mouse feces, urine, plasma, and liver. J Pharm Biomed Anal. 2025 Nov 15; 265:117034.
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Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC-MS-Based Metabolomic Approaches. Chem Res Toxicol. 2023 08 21; 36(8):1427-1438.
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Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice. Drug Metab Dispos. 2022 02; 50(2):128-139.
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Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo. Arch Toxicol. 2020 11; 94(11):3737-3749.
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Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes?. Biol Reprod. 2020 08 04; 103(2):427-436.
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Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine. Eur J Pharm Sci. 2020 Oct 01; 153:105488.
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Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5. Arch Biochem Biophys. 2018 11 01; 657:65-73.
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Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers. Bioorg Med Chem Lett. 2017 12 01; 27(23):5144-5148.
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Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD. Sci Rep. 2017 09 18; 7(1):11793.
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Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2. ACS Chem Neurosci. 2017 09 20; 8(9):1937-1948.