"Cytochrome P-450 CYP1A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
| Descriptor ID |
D019363
|
| MeSH Number(s) |
D08.244.453.005.332 D08.244.453.100.500 D08.811.682.690.708.170.010.277 D08.811.682.690.708.170.020.500 D12.776.422.220.453.010.332 D12.776.422.220.453.100.500
|
| Concept/Terms |
Cytochrome P-450 CYP1A1- Cytochrome P-450 CYP1A1
- Cytochrome P 450 CYP1A1
- EROD
- Ethoxyresorufin Dealkylase
- Ethylresorufin O-Deethylase
- CYP1A1 Protein
- 7-Ethoxyresorufin O-Deethylase
- CYP1A1
- Cytochrome P450 IA1
- Ethoxyresorufin O-Deethylase
- CYP 1A1
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A1" by people in this website by year, and whether "Cytochrome P-450 CYP1A1" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 3 | 2 | 5 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 4 | 2 | 6 |
| 2011 | 2 | 2 | 4 |
| 2012 | 1 | 2 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 4 | 0 | 4 |
| 2018 | 1 | 1 | 2 |
| 2020 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1A1" by people in Profiles.
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CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitor. Biochem Pharmacol. 2018 12; 158:174-184.
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Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome. Sci Rep. 2017 04 04; 7(1):642.
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Sex-specific differences in neonatal hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 01; 311(2):L481-93.
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The androgenic anabolic steroid tetrahydrogestrinone produces dioxin-like effects via the aryl hydrocarbon receptor. Toxicol In Vitro. 2012 Oct; 26(7):1129-33.
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Association of variants in estrogen-related pathway genes with prostate cancer risk. Prostate. 2013 Jan; 73(1):1-10.
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Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. Cancer Res. 2011 Dec 15; 71(24):7376-86.
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Beta-naphthoflavone causes an AhR-independent inhibition of invasion and intracellular multiplication of Listeria monocytogenes in murine hepatocytes. Microb Pathog. 2009 Nov; 47(5):258-66.
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PAH-DNA adducts in a Chinese population: relationship to PAH exposure, smoking and polymorphisms of metabolic and DNA repair genes. Biomarkers. 2008 Feb; 13(1):27-40.
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Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study. Mutat Res. 2005 Dec 30; 592(1-2):45-57.
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Aromatic DNA adducts and polymorphisms of CYP1A1, NAT2, and GSTM1 in breast cancer. Carcinogenesis. 2002 Feb; 23(2):301-6.