Aryl Hydrocarbon Hydroxylases
"Aryl Hydrocarbon Hydroxylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
| Descriptor ID |
D001189
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| MeSH Number(s) |
D08.244.453.005 D08.811.682.690.708.170.010 D12.776.422.220.453.010
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aryl Hydrocarbon Hydroxylases".
Below are MeSH descriptors whose meaning is more specific than "Aryl Hydrocarbon Hydroxylases".
This graph shows the total number of publications written about "Aryl Hydrocarbon Hydroxylases" by people in this website by year, and whether "Aryl Hydrocarbon Hydroxylases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 3 | 1 | 4 |
| 2005 | 3 | 0 | 3 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 1 | 5 | 6 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aryl Hydrocarbon Hydroxylases" by people in Profiles.
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Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls. Nicotine Tob Res. 2019 05 21; 21(6):714-722.
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Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5. Arch Biochem Biophys. 2018 11 01; 657:65-73.
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Bedaquiline metabolism: enzymes and novel metabolites. Drug Metab Dispos. 2014 May; 42(5):863-6.
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CYP2B6-G516T genotype influences plasma efavirenz concentration in a Hong Kong population, allowing potential individualization of therapy. HIV Med. 2014 Jan; 15(1):63-4.
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Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways. Thromb Haemost. 2013 Dec; 110(6):1223-31.
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Impact of aberrant DNA methylation patterns including CYP1B1 methylation in adolescents and young adults with acute lymphocytic leukemia. Am J Hematol. 2013 Sep; 88(9):784-9.
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Role of multiple microRNAs in the sexually dimorphic expression of Cyp2b9 in mouse liver. Drug Metab Dispos. 2013 Oct; 41(10):1732-7.
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Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia. Leuk Res. 2013 May; 37(5):531-5.
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CYP1B1 analysis of unilateral primary newborn glaucoma in Saudi children. J AAPOS. 2012 Dec; 16(6):571-2.
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CYP2C9 variants increase risk of colorectal adenoma recurrence and modify associations with smoking but not aspirin treatment. Cancer Causes Control. 2013 Jan; 24(1):47-54.