"Cytochrome P-450 CYP1A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as CAFFEINE and ACETAMINOPHEN.
Descriptor ID |
D019388
|
MeSH Number(s) |
D08.244.453.005.443 D08.244.453.100.750 D08.811.682.690.708.170.010.443 D08.811.682.690.708.170.020.750 D12.776.422.220.453.010.443 D12.776.422.220.453.100.750
|
Concept/Terms |
Cytochrome P-450 CYP1A2- Cytochrome P-450 CYP1A2
- CYP1A2, Cytochrome P-450
- Cytochrome P 450 CYP1A2
- Cytochrome P-450d
- Cytochrome P 450d
- Phenacetin O-Dealkylase
- O-Dealkylase, Phenacetin
- Phenacetin O Dealkylase
- Caffeine Demethylase
- Demethylase, Caffeine
- Cytochrome P-450 LM4
- Cytochrome P 450 LM4
- P-450 LM4, Cytochrome
- Cytochrome P450 1A2
- CYP1A2
- CYP 1A2
- Cytochrome P-450 LM(4)
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A2".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A2".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A2" by people in this website by year, and whether "Cytochrome P-450 CYP1A2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1997 | 1 | 0 | 1 |
2000 | 3 | 1 | 4 |
2002 | 2 | 2 | 4 |
2003 | 2 | 0 | 2 |
2004 | 2 | 0 | 2 |
2005 | 2 | 0 | 2 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 2 | 3 |
2010 | 2 | 0 | 2 |
2011 | 2 | 0 | 2 |
2012 | 0 | 1 | 1 |
2015 | 4 | 0 | 4 |
2017 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2022 | 0 | 2 | 2 |
2023 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cytochrome P-450 CYP1A2" by people in Profiles.
-
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1. Free Radic Biol Med. 2024 02 01; 211:35-46.
-
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation. Redox Biol. 2023 08; 64:102790.
-
The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice. Eur J Pharm Sci. 2023 Feb 01; 181:106358.
-
Coffee Intake, Caffeine Metabolism Genotype, and Survival Among Men with Prostate Cancer. Eur Urol Oncol. 2023 Jun; 6(3):282-288.
-
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2. Toxicol Sci. 2020 10 01; 177(2):347-361.
-
Coffee, Caffeine Metabolism Genotype and Disease Progression in Patients with Localized Prostate Cancer Managed with Active Surveillance. J Urol. 2019 02; 201(2):308-314.
-
?-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type and Cyp1a2-knockout mice. Toxicol Appl Pharmacol. 2018 01 15; 339:133-142.
-
Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor. Drug Metab Dispos. 2015 Dec; 43(12):1966-70.
-
Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A. Toxicology. 2015 May 04; 331:14-23.
-
Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury. Free Radic Biol Med. 2015 May; 82:147-59.