"Glucuronides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycosides of GLUCURONIC ACID formed by the reaction of URIDINE DIPHOSPHATE GLUCURONIC ACID with certain endogenous and exogenous substances. Their formation is important for the detoxification of drugs, steroid excretion and BILIRUBIN metabolism to a more water-soluble compound that can be eliminated in the URINE and BILE.
Descriptor ID |
D020719
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MeSH Number(s) |
D02.241.081.844.915.162.500 D02.241.152.811.162.750 D02.241.511.902.915.162.750 D09.811.922.162.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glucuronides".
Below are MeSH descriptors whose meaning is more specific than "Glucuronides".
This graph shows the total number of publications written about "Glucuronides" by people in this website by year, and whether "Glucuronides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2009 | 1 | 1 | 2 |
2010 | 5 | 1 | 6 |
2011 | 5 | 1 | 6 |
2012 | 4 | 1 | 5 |
2013 | 2 | 0 | 2 |
2015 | 0 | 1 | 1 |
2016 | 2 | 0 | 2 |
2017 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glucuronides" by people in Profiles.
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23,25-Dihydroxyvitamin D<sub>3</sub> is liberated as a major vitamin D<sub>3</sub> metabolite in human urine after treatment with ?-glucuronidase: Quantitative comparison with 24,25-dihydroxyvitamin D<sub>3</sub> by LC/MS/MS. J Steroid Biochem Mol Biol. 2022 Oct; 223:106133.
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Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides. Mol Pharm. 2017 09 05; 14(9):2884-2898.
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Simultaneous quantification of mycophenolic acid and its glucuronide metabolites in human plasma by an UPLC-MS/MS assay. Biomed Chromatogr. 2016 Oct; 30(10):1648-55.
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Development and validation of an UPLC-MS/MS method for the quantification of irinotecan, SN-38 and SN-38 glucuronide in plasma, urine, feces, liver and kidney: Application to a pharmacokinetic study of irinotecan in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15; 1015-1016:34-41.
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Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP. Pharm Res. 2016 Mar; 33(3):590-602.
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Validated LC-MS/MS method for the determination of 3-hydroxflavone and its glucuronide in blood and bioequivalent buffers: application to pharmacokinetic, absorption, and metabolism studies. J Pharm Biomed Anal. 2013 Nov; 85:245-52.
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Quantitative prediction of glucuronidation in humans using the in vitro- in vivo extrapolation approach. Curr Top Med Chem. 2013; 13(11):1343-52.
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A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. Mol Pharm. 2012 Nov 05; 9(11):3246-58.
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Associations of serum sex steroid hormone and 5a-androstane-3a,17?-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride. Cancer Epidemiol Biomarkers Prev. 2012 Oct; 21(10):1823-32.
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A new strategy to rapidly evaluate kinetics of glucuronide efflux by breast cancer resistance protein (BCRP/ABCG2). Pharm Res. 2012 Nov; 29(11):3199-208.