"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
| Descriptor ID |
D001667
|
| MeSH Number(s) |
E05.196.080 G02.111.084 G02.111.570.120.309
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in this website by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 7 | 7 |
| 1997 | 0 | 7 | 7 |
| 1999 | 0 | 5 | 5 |
| 2000 | 0 | 5 | 5 |
| 2001 | 0 | 5 | 5 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 6 | 6 |
| 2005 | 0 | 6 | 6 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 5 | 5 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles.
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TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. J Immunol. 2014 Jul 15; 193(2):571-9.
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Competition between Grb2 and Plc?1 for FGFR2 regulates basal phospholipase activity and invasion. Nat Struct Mol Biol. 2014 Feb; 21(2):180-8.
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Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors a- and ?-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft. Steroids. 2013 Nov; 78(11):1071-86.
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A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3. FEBS Lett. 2012 Nov 16; 586(22):3996-4001.
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The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity. Cell Host Microbe. 2012 Mar 15; 11(3):277-89.
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Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun. 2012; 3:1288.
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(124)I-iodopyridopyrimidinone for PET of Abl kinase-expressing tumors in vivo. J Nucl Med. 2010 Jan; 51(1):121-9.
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Chemical probes that competitively and selectively inhibit Stat3 activation. PLoS One. 2009; 4(3):e4783.
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Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat Chem Biol. 2008 Nov; 4(11):708-14.
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Discovery of a novel class of AKT pleckstrin homology domain inhibitors. Mol Cancer Ther. 2008 Sep; 7(9):2621-32.