"Catalytic Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
| Descriptor ID |
D020134
|
| MeSH Number(s) |
G02.111.570.120.704 G02.111.570.820.709.275.750.188
|
| Concept/Terms |
Catalytic Domain- Catalytic Domain
- Catalytic Domains
- Domain, Catalytic
- Domains, Catalytic
- Catalytic Subunit
- Catalytic Subunits
- Subunit, Catalytic
- Subunits, Catalytic
- Catalytic Region
- Catalytic Regions
- Region, Catalytic
- Regions, Catalytic
- Catalytic Core
- Catalytic Cores
- Core, Catalytic
- Cores, Catalytic
Active Site- Active Site
- Active Sites
- Site, Active
- Sites, Active
- Catalytic Site
- Catalytic Sites
- Site, Catalytic
- Sites, Catalytic
- Reactive Site
- Reactive Sites
- Site, Reactive
- Sites, Reactive
|
Below are MeSH descriptors whose meaning is more general than "Catalytic Domain".
Below are MeSH descriptors whose meaning is more specific than "Catalytic Domain".
This graph shows the total number of publications written about "Catalytic Domain" by people in this website by year, and whether "Catalytic Domain" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 2 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2004 | 1 | 4 | 5 |
| 2005 | 1 | 5 | 6 |
| 2006 | 0 | 4 | 4 |
| 2007 | 2 | 2 | 4 |
| 2008 | 0 | 4 | 4 |
| 2009 | 2 | 6 | 8 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 8 | 8 |
| 2012 | 1 | 8 | 9 |
| 2013 | 0 | 5 | 5 |
| 2014 | 1 | 6 | 7 |
| 2015 | 0 | 8 | 8 |
| 2016 | 0 | 8 | 8 |
| 2017 | 0 | 4 | 4 |
| 2018 | 1 | 4 | 5 |
| 2019 | 1 | 4 | 5 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 5 | 6 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 4 | 5 |
| 2024 | 0 | 2 | 2 |
| 2025 | 0 | 4 | 4 |
| 2026 | 0 | 3 | 3 |
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click here.
Below are the most recent publications written about "Catalytic Domain" by people in Profiles.
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Functional dynamics of water in New Delhi metallo-?-lactamase catalysis. Protein Sci. 2026 Jun; 35(6):e70633.
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Conformational gating mechanism for processive catalysis of ?(1,3)-glucans. Nat Commun. 2026 Mar 27; 17(1).
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Phosphate sensitivity of KPC-2: a hidden variable in ?-lactamase kinetics. Antimicrob Agents Chemother. 2026 Mar 04; 70(3):e0106925.
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A protective and heterosubtypic antibody lineage targeting the influenza A virus neuraminidase active site. J Clin Invest. 2025 12 01; 135(23).
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Structural basis for mTORC1 activation on the lysosomal membrane. Nature. 2025 11; 647(8089):536-543.
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Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis. Nat Commun. 2025 Jul 21; 16(1):6704.
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Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding. ACS Infect Dis. 2025 Feb 14; 11(2):442-452.
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Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors. J Virol. 2025 02 25; 99(2):e0175724.
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Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans. Nucleic Acids Res. 2024 05 22; 52(9):4985-5001.
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Network of epistatic interactions in an enzyme active site revealed by large-scale deep mutational scanning. Proc Natl Acad Sci U S A. 2024 Mar 19; 121(12):e2313513121.