"Catalytic Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
| Descriptor ID |
D020134
|
| MeSH Number(s) |
G02.111.570.120.704 G02.111.570.820.709.275.750.188
|
| Concept/Terms |
Catalytic Domain- Catalytic Domain
- Catalytic Domains
- Domain, Catalytic
- Domains, Catalytic
- Catalytic Subunit
- Catalytic Subunits
- Subunit, Catalytic
- Subunits, Catalytic
- Catalytic Region
- Catalytic Regions
- Region, Catalytic
- Regions, Catalytic
- Catalytic Core
- Catalytic Cores
- Core, Catalytic
- Cores, Catalytic
Active Site- Active Site
- Active Sites
- Site, Active
- Sites, Active
- Catalytic Site
- Catalytic Sites
- Site, Catalytic
- Sites, Catalytic
- Reactive Site
- Reactive Sites
- Site, Reactive
- Sites, Reactive
|
Below are MeSH descriptors whose meaning is more general than "Catalytic Domain".
Below are MeSH descriptors whose meaning is more specific than "Catalytic Domain".
This graph shows the total number of publications written about "Catalytic Domain" by people in this website by year, and whether "Catalytic Domain" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 2 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2004 | 1 | 4 | 5 |
| 2005 | 1 | 5 | 6 |
| 2006 | 0 | 4 | 4 |
| 2007 | 2 | 2 | 4 |
| 2008 | 0 | 4 | 4 |
| 2009 | 2 | 6 | 8 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 8 | 8 |
| 2012 | 1 | 8 | 9 |
| 2013 | 0 | 5 | 5 |
| 2014 | 1 | 6 | 7 |
| 2015 | 0 | 8 | 8 |
| 2016 | 0 | 8 | 8 |
| 2017 | 0 | 4 | 4 |
| 2018 | 1 | 4 | 5 |
| 2019 | 1 | 4 | 5 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 5 | 6 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 4 | 5 |
| 2024 | 0 | 2 | 2 |
| 2025 | 0 | 4 | 4 |
| 2026 | 0 | 5 | 5 |
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click here.
Below are the most recent publications written about "Catalytic Domain" by people in Profiles.
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Molecular determinants for a-tubulin methylation by SETD2. J Biol Chem. 2021 07; 297(1):100898.
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High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13. Sci Rep. 2018 02 12; 8(1):2788.
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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7):1901-6.
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Structural Basis for Different Substrate Profiles of Two Closely Related Class D ?-Lactamases and Their Inhibition by Halogens. Biochemistry. 2015 Jun 02; 54(21):3370-80.
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TP53 loss creates therapeutic vulnerability in?colorectal cancer. Nature. 2015 Apr 30; 520(7549):697-701.
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On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Cell. 2015 Feb 12; 160(4):644-658.
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The ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in aII b ?3 integrin signaling. J Thromb Haemost. 2014 Dec; 12(12):2089-101.
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C-terminal domain (CTD) small phosphatase-like 2 modulates the canonical bone morphogenetic protein (BMP) signaling and mesenchymal differentiation via Smad dephosphorylation. J Biol Chem. 2014 Sep 19; 289(38):26441-26450.
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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells. Nucleic Acids Res. 2014 Jun; 42(11):6956-71.
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Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx. Cell Signal. 2013 Apr; 25(4):796-804.