"Kringles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Triple-looped protein domains linked by disulfide bonds. These common structural domains, so-named for their resemblance to Danish pastries known as kringlers, play a role in binding membranes, proteins, and phospholipids as well as in regulating proteolysis. Kringles are also present in coagulation-related and fibrinolytic proteins and other plasma proteinases.
| Descriptor ID |
D018082
|
| MeSH Number(s) |
G02.111.570.820.709.275.750.375
|
| Concept/Terms |
Kringles- Kringles
- Kringle
- Kringle Domains
- Domain, Kringle
- Domains, Kringle
- Kringle Domain
|
Below are MeSH descriptors whose meaning is more general than "Kringles".
Below are MeSH descriptors whose meaning is more specific than "Kringles".
This graph shows the total number of publications written about "Kringles" by people in this website by year, and whether "Kringles" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kringles" by people in Profiles.
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Targeted antivascular therapy with the apolipoprotein(a) kringle V, rhLK8, inhibits the growth and metastasis of human prostate cancer in an orthotopic nude mouse model. Neoplasia. 2012 Apr; 14(4):335-43.
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Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen. Blood. 2011 Aug 11; 118(6):1653-62.
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Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans. PLoS One. 2011 Jan 24; 6(1):e14581.
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Lupus-derived antiprothrombin autoantibodies from a V gene phage display library are specific for the kringle 2 domain of prothrombin. Biochemistry. 2004 Apr 06; 43(13):4047-54.
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Kringle domains of human angiostatin. Characterization of the anti-proliferative activity on endothelial cells. J Biol Chem. 1996 Nov 15; 271(46):29461-7.
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Electrophoretic methods for quantitation of lipoprotein [a]. Methods Enzymol. 1996; 263:218-37.