"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
|
| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 4 | 5 |
| 1995 | 2 | 7 | 9 |
| 1996 | 3 | 0 | 3 |
| 1997 | 1 | 4 | 5 |
| 1998 | 6 | 5 | 11 |
| 1999 | 5 | 7 | 12 |
| 2000 | 2 | 13 | 15 |
| 2001 | 3 | 9 | 12 |
| 2002 | 1 | 7 | 8 |
| 2003 | 3 | 20 | 23 |
| 2004 | 3 | 18 | 21 |
| 2005 | 3 | 10 | 13 |
| 2006 | 3 | 13 | 16 |
| 2007 | 6 | 20 | 26 |
| 2008 | 4 | 9 | 13 |
| 2009 | 3 | 17 | 20 |
| 2010 | 2 | 11 | 13 |
| 2011 | 5 | 2 | 7 |
| 2012 | 5 | 7 | 12 |
| 2013 | 10 | 11 | 21 |
| 2014 | 3 | 6 | 9 |
| 2015 | 4 | 6 | 10 |
| 2016 | 5 | 8 | 13 |
| 2017 | 3 | 8 | 11 |
| 2018 | 4 | 5 | 9 |
| 2019 | 6 | 7 | 13 |
| 2020 | 7 | 5 | 12 |
| 2021 | 3 | 5 | 8 |
| 2022 | 2 | 5 | 7 |
| 2023 | 2 | 6 | 8 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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?-Actin G342D as a Cause of NK Cell Deficiency Impairing Lytic Synapse Termination. J Immunol. 2024 Mar 15; 212(6):962-973.
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Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha. FASEB J. 2024 01; 38(1):e23346.
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PLS3 missense variants affecting the actin-binding domains cause X-linked congenital diaphragmatic hernia and body-wall defects. Am J Hum Genet. 2023 10 05; 110(10):1787-1803.
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Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis. Cancer Res. 2023 09 01; 83(17):2889-2907.
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Presynapses contain distinct actin nanostructures. J Cell Biol. 2023 10 02; 222(10).
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A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Cell Rep. 2023 08 29; 42(8):112842.
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Taking shape: Intercalation within the mammary terminal end bud. Dev Cell. 2023 07 10; 58(13):1123-1125.
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Tiam1 coordinates synaptic structural and functional plasticity underpinning the pathophysiology of neuropathic pain. Neuron. 2023 07 05; 111(13):2038-2050.e6.
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Circadian clock control of MRTF/SRF pathway suppresses beige adipocyte thermogenic recruitment. J Mol Cell Biol. 2023 04 20; 14(12).
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De novo variants in MRTFB have gain-of-function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features. Genet Med. 2023 06; 25(6):100833.