"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
|
| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 3 | 4 | 7 |
| 1999 | 2 | 5 | 7 |
| 2000 | 2 | 5 | 7 |
| 2001 | 1 | 3 | 4 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 6 | 7 |
| 2004 | 0 | 10 | 10 |
| 2005 | 2 | 1 | 3 |
| 2006 | 1 | 8 | 9 |
| 2007 | 2 | 8 | 10 |
| 2008 | 2 | 3 | 5 |
| 2009 | 2 | 8 | 10 |
| 2010 | 2 | 5 | 7 |
| 2011 | 4 | 1 | 5 |
| 2012 | 2 | 4 | 6 |
| 2013 | 4 | 5 | 9 |
| 2014 | 3 | 4 | 7 |
| 2015 | 4 | 5 | 9 |
| 2016 | 3 | 4 | 7 |
| 2017 | 4 | 7 | 11 |
| 2018 | 2 | 3 | 5 |
| 2019 | 3 | 3 | 6 |
| 2020 | 5 | 2 | 7 |
| 2021 | 1 | 4 | 5 |
| 2022 | 1 | 5 | 6 |
| 2023 | 1 | 5 | 6 |
| 2024 | 4 | 2 | 6 |
| 2025 | 1 | 2 | 3 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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ACTA2 Pathogenic Variants Activating Heat Shock Factor 1 and Increasing Cholesterol Biosynthesis in Smooth Muscle Cells Predispose to Early Onset Atherosclerosis. Circ Genom Precis Med. 2026 Feb; 19(1):e005169.
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Immature Acta2R179C/+ smooth muscle cells cause moyamoya-like cerebrovascular lesions in mice prevented by boosting OXPHOS. Nat Commun. 2025 Jul 02; 16(1):6105.
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Influence of lung extracellular matrix from non-IPF and IPF donors on primary human lung fibroblast biology. Biomater Sci. 2025 Mar 25; 13(7):1721-1741.
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Osteoprotegerin is induced by transforming growth factor-beta 1 and regulates pro-fibrotic responses in human dermal fibroblasts. Biochem Biophys Res Commun. 2025 03 25; 754:151524.
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The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis and maintain translational repression of maternal mRNA and oocyte quality. Mol Biol Cell. 2024 Oct 01; 35(10):ar131.
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SETD3 is a mechanosensitive enzyme that methylates actin on His73 to regulate mitochondrial dynamics and function. J Cell Sci. 2024 07 15; 137(14).
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Ciliary tip actin dynamics regulate photoreceptor outer segment integrity. Nat Commun. 2024 May 21; 15(1):4316.
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?-Actin G342D as a Cause of NK Cell Deficiency Impairing Lytic Synapse Termination. J Immunol. 2024 Mar 15; 212(6):962-973.
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Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry. Sci Adv. 2024 02 09; 10(6):eadi7840.
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Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha. FASEB J. 2024 01; 38(1):e23346.