Actin-Related Protein 2-3 Complex
"Actin-Related Protein 2-3 Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex of seven proteins including ARP2 PROTEIN and ARP3 PROTEIN that plays an essential role in maintenance and assembly of the CYTOSKELETON. Arp2-3 complex binds WASP PROTEIN and existing ACTIN FILAMENTS, and it nucleates the formation of new branch point filaments.
| Descriptor ID |
D051376
|
| MeSH Number(s) |
D05.750.078.730.246 D12.776.220.525.246
|
| Concept/Terms |
Actin-Related Protein 2-3 Complex- Actin-Related Protein 2-3 Complex
- Actin Related Protein 2 3 Complex
- Arp2-3 Complex
- Arp2 3 Complex
- Arp2-3 Protein Complex
- Arp2 3 Protein Complex
|
Below are MeSH descriptors whose meaning is more general than "Actin-Related Protein 2-3 Complex".
Below are MeSH descriptors whose meaning is more specific than "Actin-Related Protein 2-3 Complex".
This graph shows the total number of publications written about "Actin-Related Protein 2-3 Complex" by people in this website by year, and whether "Actin-Related Protein 2-3 Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Actin-Related Protein 2-3 Complex" by people in Profiles.
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Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 07; 583(7814):90-95.
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A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency. J Allergy Clin Immunol. 2019 06; 143(6):2296-2299.
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Advillin acts upstream of phospholipase C ?1 in steroid-resistant nephrotic syndrome. J Clin Invest. 2017 12 01; 127(12):4257-4269.
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Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med. 2016 11; 22(11):1294-1302.
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Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell. 2016 Apr 07; 165(2):434-448.
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SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature. 2013 Nov 07; 503(7474):72-7.
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Secreted VAPB/ALS8 major sperm protein domains modulate mitochondrial localization and morphology via growth cone guidance receptors. Dev Cell. 2012 Feb 14; 22(2):348-62.
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Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe. Mol Biol Cell. 2010 Sep 15; 21(18):3125-36.
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Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. J Cell Biol. 2010 Jul 12; 190(1):101-14.
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The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors. Nat Cell Biol. 2009 Jul; 11(7):815-24.