Actin Depolymerizing Factors
"Actin Depolymerizing Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
| Descriptor ID |
D051339
|
| MeSH Number(s) |
D05.750.078.730.212 D12.776.220.525.212
|
| Concept/Terms |
Actin Depolymerizing Factors- Actin Depolymerizing Factors
- Depolymerizing Factors, Actin
- Cofilins
- Cofilin Proteins
- Actin Depolymerizing Proteins
- Depolymerizing Proteins, Actin
- ADF Proteins (Actin Depolymerizing Factors)
|
Below are MeSH descriptors whose meaning is more general than "Actin Depolymerizing Factors".
Below are MeSH descriptors whose meaning is more specific than "Actin Depolymerizing Factors".
This graph shows the total number of publications written about "Actin Depolymerizing Factors" by people in this website by year, and whether "Actin Depolymerizing Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Actin Depolymerizing Factors" by people in Profiles.
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Altered Actin Filament Dynamics in the Drosophila Mushroom Bodies Lead to Fast Acquisition of Alcohol Consumption Preference. J Neurosci. 2019 11 06; 39(45):8877-8884.
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Cofilin-Mediated Actin Stress Response Is Maladaptive in Heat-Stressed Embryos. Cell Rep. 2019 03 26; 26(13):3493-3501.e4.
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-Back-to-back mechanisms drive actomyosin ring closure during Drosophila embryo cleavage. J Cell Biol. 2016 Nov 07; 215(3):335-344.
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RhoGAP18B Isoforms Act on Distinct Rho-Family GTPases and Regulate Behavioral Responses to Alcohol via Cofilin. PLoS One. 2015; 10(9):e0137465.
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Streptococcus pneumoniae ClpL modulates adherence to A549 human lung cells through Rap1/Rac1 activation. Infect Immun. 2014 Sep; 82(9):3802-10.
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Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons. J Biol Chem. 2012 Feb 03; 287(6):3919-29.
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14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes. Biochem Biophys Res Commun. 2009 Jun 12; 383(4):450-4.
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Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia. Blood. 2007 Oct 01; 110(7):2371-80.
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Expression of rotavirus NSP4 alters the actin network organization through the actin remodeling protein cofilin. J Virol. 2007 Apr; 81(7):3545-53.
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ADF/cofilin weakens lateral contacts in the actin filament. J Mol Biol. 1999 Aug 20; 291(3):513-9.