"C2 Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.
| Descriptor ID |
D000070538
|
| MeSH Number(s) |
G02.111.570.820.709.275.750.125
|
| Concept/Terms |
C2 Domains- C2 Domains
- Domain, C2
- Domains, C2
- C2 Domain
C2 Tensin-type Domain- C2 Tensin-type Domain
- C2 Tensin type Domain
- C2 Tensin-type Domains
- Domain, C2 Tensin-type
- Domains, C2 Tensin-type
- Tensin-type Domain, C2
- Tensin-type Domains, C2
|
Below are MeSH descriptors whose meaning is more general than "C2 Domains".
Below are MeSH descriptors whose meaning is more specific than "C2 Domains".
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