"Protein Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.
Descriptor ID |
D000072417
|
MeSH Number(s) |
G02.111.570.820.709.275.750 G02.111.570.820.709.610.500
|
Concept/Terms |
Protein Domains- Protein Domains
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domain
- Domain, Protein
- Domains, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Domains".
Below are MeSH descriptors whose meaning is more specific than "Protein Domains".
This graph shows the total number of publications written about "Protein Domains" by people in this website by year, and whether "Protein Domains" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 21 | 22 |
2017 | 0 | 28 | 28 |
2018 | 0 | 23 | 23 |
2019 | 2 | 14 | 16 |
2020 | 2 | 30 | 32 |
2021 | 0 | 40 | 40 |
2022 | 0 | 9 | 9 |
2023 | 0 | 5 | 5 |
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Below are the most recent publications written about "Protein Domains" by people in Profiles.
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Refining chimeric antigen receptors via barcoded protein domain combination pooled screening. Mol Ther. 2023 11 01; 31(11):3210-3224.
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Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria. Nat Commun. 2023 04 11; 14(1):2028.
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PAK1 c.1409?T?>?a (p. Leu470Gln) de novo variant affects the protein kinase domain, leading to epilepsy, macrocephaly, spastic quadriplegia, and hydrocephalus: Case report and review of the literature. Am J Med Genet A. 2023 06; 191(6):1619-1625.
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Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410-DNA interaction using small angle X-ray scattering. Nucleic Acids Res. 2023 02 28; 51(4):1674-1686.
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Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia. J Biol Chem. 2023 02; 299(2):102885.
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A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2. J Biol Chem. 2023 02; 299(2):102862.
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Conformational motions and ligand-binding underlying gating and regulation in IP3R channel. Nat Commun. 2022 11 14; 13(1):6942.
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Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2207408119.
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De Novo ZMYND8 variants result in an autosomal dominant neurodevelopmental disorder with cardiac malformations. Genet Med. 2022 09; 24(9):1952-1966.
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Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections. Proc Natl Acad Sci U S A. 2022 05 31; 119(22):e2122506119.