Protein Interaction Domains and Motifs
"Protein Interaction Domains and Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein modules with conserved ligand-binding surfaces which mediate specific interaction functions in SIGNAL TRANSDUCTION PATHWAYS and the specific BINDING SITES of their cognate protein LIGANDS.
| Descriptor ID |
D054730
|
| MeSH Number(s) |
G02.111.570.820.709.275.750.500
|
| Concept/Terms |
Protein Interaction Motifs- Protein Interaction Motifs
- Motif, Protein Interaction
- Motifs, Protein Interaction
- Protein Interaction Motif
- Binding Motifs, Protein Interaction
- Protein Interaction Binding Motifs
Protein Interaction Domains- Protein Interaction Domains
- Domain, Protein Interaction
- Domains, Protein Interaction
- Protein Interaction Domain
- Protein-Protein Interaction Domains
- Domain, Protein-Protein Interaction
- Domains, Protein-Protein Interaction
- Protein Protein Interaction Domains
- Protein-Protein Interaction Domain
|
Below are MeSH descriptors whose meaning is more general than "Protein Interaction Domains and Motifs".
Below are MeSH descriptors whose meaning is more specific than "Protein Interaction Domains and Motifs".
This graph shows the total number of publications written about "Protein Interaction Domains and Motifs" by people in this website by year, and whether "Protein Interaction Domains and Motifs" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 10 | 10 |
| 2012 | 1 | 3 | 4 |
| 2013 | 3 | 8 | 11 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 5 | 5 |
| 2016 | 2 | 7 | 9 |
| 2017 | 0 | 12 | 12 |
| 2018 | 1 | 5 | 6 |
| 2019 | 1 | 6 | 7 |
| 2020 | 0 | 7 | 7 |
| 2021 | 0 | 9 | 9 |
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Below are the most recent publications written about "Protein Interaction Domains and Motifs" by people in Profiles.
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Molecular Basis for SPINDOC-Spindlin1 Engagement and Its Role in Transcriptional Attenuation. J Mol Biol. 2024 Apr 01; 436(7):168371.
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A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses. Emerg Microbes Infect. 2022 Dec; 11(1):147-157.
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A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science. 2021 Nov 26; 374(6571):1113-1121.
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SPINDOC binds PARP1 to facilitate PARylation. Nat Commun. 2021 11 04; 12(1):6362.
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Norovirus Protease Structure and Antivirals Development. Viruses. 2021 10 14; 13(10).
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Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses. Cell Rep. 2021 10 05; 37(1):109771.
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Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization. Nat Commun. 2021 09 22; 12(1):5579.
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Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition. Cell Rep. 2021 10 05; 37(1):109784.
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Structure and function of an Arabidopsis thaliana sulfate transporter. Nat Commun. 2021 07 22; 12(1):4455.
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Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth. Theranostics. 2021; 11(17):8172-8184.