"Ankyrin Repeat" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was discovered in ANKYRIN where it is involved in interaction with the anion exchanger (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE). Ankyrin repeats cooperatively fold into domains that mediate molecular recognition via protein-protein interactions.
| Descriptor ID |
D017089
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| MeSH Number(s) |
G02.111.570.060.720.030 G02.111.570.820.709.275.500.030 G02.111.570.820.709.275.750.500.080 G02.111.570.820.709.275.875.030
|
| Concept/Terms |
Ankyrin Repeat- Ankyrin Repeat
- Repeat, Ankyrin
- Repeats, Ankyrin
- Ankyrin Repeats
- ANK Repeat
- ANK Repeats
- Repeat, ANK
- Repeats, ANK
Ankyrin-Like Repeats- Ankyrin-Like Repeats
- Ankyrin Like Repeats
- Ankyrin-Like Repeat
- Repeat, Ankyrin-Like
- Repeats, Ankyrin-Like
ANK Repeat Domains- ANK Repeat Domains
- ANK Repeat Domain
- Domain, ANK Repeat
- Domains, ANK Repeat
- Repeat Domain, ANK
- Repeat Domains, ANK
- Ankyrin Repeat Domains
- Ankyrin Repeat Domain
- Domain, Ankyrin Repeat
- Domains, Ankyrin Repeat
- Repeat Domain, Ankyrin
- Repeat Domains, Ankyrin
|
Below are MeSH descriptors whose meaning is more general than "Ankyrin Repeat".
Below are MeSH descriptors whose meaning is more specific than "Ankyrin Repeat".
This graph shows the total number of publications written about "Ankyrin Repeat" by people in this website by year, and whether "Ankyrin Repeat" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ankyrin Repeat" by people in Profiles.
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TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p. Nat Commun. 2017 10 16; 8(1):947.
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ZASP interacts with the mechanosensing protein Ankrd2 and p53 in the signalling network of striated muscle. PLoS One. 2014; 9(3):e92259.
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Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Mol Cell. 2014 Jan 23; 53(2):221-34.
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Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):E869-77.
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In silico analysis reveals the presence of a large number of Ankyrin repeat containing proteins in Ectocarpus siliculosus. Interdiscip Sci. 2012 Dec; 4(4):291-5.
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Treatment of diabetic macular edema with a designed ankyrin repeat protein that binds vascular endothelial growth factor: a phase I/II study. Am J Ophthalmol. 2013 Apr; 155(4):697-704, 704.e1-2.
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Designed ankyrin repeat proteins as scaffolds for multivalent recognition. Biomacromolecules. 2012 Jul 09; 13(7):1996-2002.
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Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting. J Mol Biol. 2011 Jan 14; 405(2):410-26.
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Functional diversity of ankyrin repeats in microbial proteins. Trends Microbiol. 2010 Mar; 18(3):132-9.
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Structure of TRPV1 channel revealed by electron cryomicroscopy. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7451-5.