"Helix-Loop-Helix Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recurring supersecondary structures characterized by 20 amino acids folding into two alpha helices connected by a non-helical "loop" segment. They are found in many sequence-specific DNA-BINDING PROTEINS and in CALCIUM-BINDING PROTEINS.
| Descriptor ID |
D018257
|
| MeSH Number(s) |
G02.111.570.820.709.275.500.360
|
| Concept/Terms |
Helix-Loop-Helix Motifs- Helix-Loop-Helix Motifs
- Helix Loop Helix Motifs
- Motif, Helix-Loop-Helix
- Helix-Loop-Helix Domains
- Helix Loop Helix Domains
- Helix-Loop-Helix Motif
- Helix Loop Helix Motif
- Helix-Loop-Helix Domain
- Helix Loop Helix Domain
- HLH Motifs
- HLH Motif
- Motif, HLH
- Motifs, HLH
- Motifs, Helix-Loop-Helix
- Motifs, Helix Loop Helix
|
Below are MeSH descriptors whose meaning is more general than "Helix-Loop-Helix Motifs".
Below are MeSH descriptors whose meaning is more specific than "Helix-Loop-Helix Motifs".
This graph shows the total number of publications written about "Helix-Loop-Helix Motifs" by people in this website by year, and whether "Helix-Loop-Helix Motifs" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 2 | 3 |
| 1998 | 0 | 2 | 2 |
| 2000 | 2 | 4 | 6 |
| 2001 | 0 | 3 | 3 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Helix-Loop-Helix Motifs" by people in Profiles.
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Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system. Dev Biol. 2005 Feb 15; 278(2):301-9.
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Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells. Br J Cancer. 2002 Jun 17; 86(12):1914-9.
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Tbx19, a tissue-selective regulator of POMC gene expression. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8674-9.
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Overexpression of BETA2/NeuroD induces neurite outgrowth in F11 neuroblastoma cells. J Neurochem. 2001 Apr; 77(1):103-9.
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BETA2 and pancreatic islet development. Recent Prog Horm Res. 2001; 56:23-46.
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Requirement for math5 in the development of retinal ganglion cells. Genes Dev. 2001 Jan 01; 15(1):24-9.
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Fusion of the NH2-terminal domain of the basic helix-loop-helix protein TCF12 to TEC in extraskeletal myxoid chondrosarcoma with translocation t(9;15)(q22;q21). Cancer Res. 2000 Dec 15; 60(24):6832-5.
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Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. Genes Dev. 2000 Nov 15; 14(22):2839-54.
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Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus. J Neurosci. 2000 May 15; 20(10):3714-24.
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The kappaB and V(D)J recombination signal sequence binding protein KRC regulates transcription of the mouse metastasis-associated gene S100A4/mts1. J Biol Chem. 2000 Jan 14; 275(2):913-20.