"Spinocerebellar Ataxias" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of dominantly inherited, predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
| Descriptor ID |
D020754
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| MeSH Number(s) |
C10.228.140.252.190.530 C10.228.140.252.700.700 C10.228.854.787.875 C10.574.500.825.700 C10.597.350.090.500.530 C16.320.400.780.875
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| Concept/Terms |
Spinocerebellar Ataxias- Spinocerebellar Ataxias
- Ataxia, Spinocerebellar
- Ataxias, Spinocerebellar
- Spinocerebellar Ataxia
- Dominantly-Inherited Spinocerebellar Ataxias
- Ataxia, Dominantly-Inherited Spinocerebellar
- Ataxias, Dominantly-Inherited Spinocerebellar
- Dominantly Inherited Spinocerebellar Ataxias
- Dominantly-Inherited Spinocerebellar Ataxia
- Spinocerebellar Ataxia, Dominantly-Inherited
- Spinocerebellar Ataxias, Dominantly-Inherited
- Spinocerebellar Ataxias, Dominantly Inherited
- Spinocerebellar Atrophies
- Atrophies, Spinocerebellar
- Atrophy, Spinocerebellar
- Spinocerebellar Atrophy
Spinocerebellar Ataxia Type 2- Spinocerebellar Ataxia Type 2
- Type 2 Spinocerebellar Ataxia
- Spinocerebellar Ataxia 2
- Ataxia 2, Spinocerebellar
- Ataxia 2s, Spinocerebellar
- Spinocerebellar Ataxia 2s
- Wadia-Swami Syndrome
- Syndrome, Wadia-Swami
- Cerebellar Degeneration with Slow Eye Movements
- Olivopontocerebellar Atrophy II
- Atrophy II, Olivopontocerebellar
- Atrophy IIs, Olivopontocerebellar
- II, Olivopontocerebellar Atrophy
- IIs, Olivopontocerebellar Atrophy
- Olivopontocerebellar Atrophy IIs
- Spinocerebellar Atrophy II
- Atrophy II, Spinocerebellar
- Atrophy IIs, Spinocerebellar
- II, Spinocerebellar Atrophy
- IIs, Spinocerebellar Atrophy
- Spinocerebellar Atrophy IIs
- Olivopontocerebellar Atrophy 2
- Atrophy 2, Olivopontocerebellar
- Atrophy 2s, Olivopontocerebellar
- Olivopontocerebellar Atrophy 2s
- Spinocerebellar Ataxia with Slow Eye Movements
- Spinocerebellar Ataxia, Cuban Type
- Spinocerebellar Atrophy 2
- Atrophy 2, Spinocerebellar
- Atrophy 2s, Spinocerebellar
- Spinocerebellar Atrophy 2s
- Spinocerebellar Degeneration with Slow Eye Movements
- Wadia Swami Syndrome
- Swami Syndrome, Wadia
- Syndrome, Wadia Swami
- Olivopontocerebellar Atrophy, Holguin Type
- Spinocerebellar Ataxia-2
Spinocerebellar Ataxia Type 7- Spinocerebellar Ataxia Type 7
- Type 7 Spinocerebellar Ataxia
- OPCA with Retinal Degeneration
- Olivopontocerebellar Atrophy III
- Atrophy III, Olivopontocerebellar
- Olivopontocerebellar Atrophy IIIs
- Autosomal Dominant Cerebellar Ataxia, Type II
- OPCA with Macular Degeneration and External Ophthalmoplegia
- Spinocerebellar Ataxia-7
- Spinocerebellar Ataxia 7
- Ataxia 7, Spinocerebellar
- Ataxia 7s, Spinocerebellar
- Spinocerebellar Ataxia 7s
Spinocerebellar Ataxia Type 5- Spinocerebellar Ataxia Type 5
- Type 5 Spinocerebellar Ataxia
- Spinocerebellar Ataxia 5
- Ataxia 5, Spinocerebellar
- Ataxia 5s, Spinocerebellar
- Spinocerebellar Ataxia 5s
- Spinocerebellar Ataxia-5
Spinocerebellar Ataxia Type 6- Spinocerebellar Ataxia Type 6
- Type 6 Spinocerebellar Ataxia
- Spinocerebellar Ataxia 6
- Ataxia 6, Spinocerebellar
- Ataxia 6s, Spinocerebellar
- Spinocerebellar Ataxia 6s
- Spinocerebellar Ataxia-6
Spinocerebellar Ataxia Type 1- Spinocerebellar Ataxia Type 1
- Type 1 Spinocerebellar Ataxia
- Spinocerebellar Ataxia 1
- Ataxia 1, Spinocerebellar
- Spinocerebellar Ataxia 1s
- Spinocerebellar Atrophy I
- Atrophy I, Spinocerebellar
- Spinocerebellar Atrophy Is
- SCA1
- SCA1s
- Cerebelloparenchymal Disorder I
- Cerebelloparenchymal Disorder Is
- Menzel Type OPCA
- OPCA, Menzel Type
- Schut-Haymaker Type OPCA
- OPCA, Schut-Haymaker Type
- Schut Haymaker Type OPCA
- Olivopontocerebellar Atrophy IV
- Atrophy IV, Olivopontocerebellar
- Atrophy IVs, Olivopontocerebellar
- Olivopontocerebellar Atrophy IVs
- Spinocerebellar Ataxia-1
- Olivopontocerebellar Atrophy I
- Atrophy I, Olivopontocerebellar
- Olivopontocerebellar Atrophy Is
Spinocerebellar Ataxia Type 4- Spinocerebellar Ataxia Type 4
- Spinocerebellar Ataxia 4
- Ataxia 4, Spinocerebellar
- Ataxia 4s, Spinocerebellar
- Spinocerebellar Ataxia 4s
- Spinocerebellar Ataxia, Autosomal Dominant, with Sensory Axonal Neuropathy
- Spinocerebellar Ataxia-4
- Type 4 Spinocerebellar Ataxia
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Below are MeSH descriptors whose meaning is more general than "Spinocerebellar Ataxias".
Below are MeSH descriptors whose meaning is more specific than "Spinocerebellar Ataxias".
This graph shows the total number of publications written about "Spinocerebellar Ataxias" by people in this website by year, and whether "Spinocerebellar Ataxias" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 |
| 2002 | 5 | 0 | 5 |
| 2003 | 5 | 2 | 7 |
| 2004 | 7 | 0 | 7 |
| 2005 | 5 | 2 | 7 |
| 2006 | 1 | 1 | 2 |
| 2007 | 8 | 2 | 10 |
| 2008 | 5 | 2 | 7 |
| 2009 | 1 | 0 | 1 |
| 2010 | 4 | 0 | 4 |
| 2011 | 7 | 0 | 7 |
| 2012 | 6 | 2 | 8 |
| 2013 | 13 | 6 | 19 |
| 2014 | 3 | 0 | 3 |
| 2015 | 8 | 0 | 8 |
| 2016 | 4 | 0 | 4 |
| 2017 | 9 | 0 | 9 |
| 2018 | 10 | 0 | 10 |
| 2019 | 4 | 2 | 6 |
| 2020 | 11 | 1 | 12 |
| 2021 | 6 | 2 | 8 |
| 2022 | 11 | 0 | 11 |
| 2023 | 3 | 0 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Spinocerebellar Ataxias" by people in Profiles.
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Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1. Neuron. 2024 Feb 07; 112(3):362-383.e15.
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Baseline Clinical and Blood Biomarkers in Patients With Preataxic and Early-Stage Disease Spinocerebellar Ataxia 1 and 3. Neurology. 2023 04 25; 100(17):e1836-e1848.
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BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1. Neurobiol Dis. 2023 03; 178:106023.
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Clinically Meaningful Magnetic Resonance Endpoints Sensitive to Preataxic Spinocerebellar Ataxia Types 1 and 3. Ann Neurol. 2023 Apr; 93(4):686-701.
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Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles. Neuron. 2023 02 15; 111(4):493-507.e6.
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Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023 02 15; 111(4):481-492.e8.
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Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2. Cell Rep. 2022 10 25; 41(4):111508.
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Spatial and Temporal Diversity of Astrocyte Phenotypes in Spinocerebellar Ataxia Type 1 Mice. Cells. 2022 10 21; 11(20).
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Objective Assessment of Upper-Extremity Motor Functions in Spinocerebellar Ataxia Using Wearable Sensors. Sensors (Basel). 2022 Oct 20; 22(20).
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The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications. Cerebellum. 2023 Oct; 22(5):790-809.