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PAUL OVERBEEK

TitleProfessor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Human Genetics
    DivisionMolecular & Human Genetics


    Collapse Research 
    Collapse research activities and funding
    U01MH078843     (OVERBEEK, PAUL A.)Sep 12, 2006 - Aug 31, 2011
    NIH
    Generation and validation of inducible Cre driver lines by enhancer trapping
    Role: Principal Investigator
    R01AR045316     (OVERBEEK, PAUL A.)Apr 25, 1998 - Mar 31, 2004
    NIH
    DOWNLESS GENE AND ITS ROLE IN INDUCTIVE SIGNALING
    Role: Principal Investigator
    R01EY010803     (OVERBEEK, PAUL A.)Sep 1, 1994 - Aug 31, 2000
    NIH
    CELL CYCLE AND CELL DEATH STUDIES IN THE OCULAR LENS
    Role: Principal Investigator
    R01EY010448     (OVERBEEK, PAUL A.)Jan 1, 1994 - May 31, 2005
    NIH
    GROWTH FACTORS AND OCULAR MORPHOGENESIS
    Role: Principal Investigator
    R01EY011348     (OVERBEEK, PAUL A.)Apr 1, 1989 - Aug 31, 1999
    NIH
    TARGETED MUTAGENESIS TO STUDY OCULAR DEVELOPMENT
    Role: Principal Investigator
    R01HD025340     (OVERBEEK, PAUL A.)Apr 1, 1989 - Dec 31, 1994
    NIH
    TRANSGENIC MICE WITH DEVELOPMENTAL DISORDERS
    Role: Principal Investigator
    R29HD024306     (OVERBEEK, PAUL A.)Jun 1, 1988 - Mar 31, 1994
    NIH
    A GENE ESSENTIAL FOR NORMAL FOOT MORPHOGENESIS
    Role: Principal Investigator
    R01EY006762     (OVERBEEK, PAUL A.)Jan 1, 1987 - Jun 30, 1994
    NIH
    MODIFICATION OF LENS CRYSTALLINS;ROLE IN CATARACTS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mattiske D, Bernard P, Gradie PE, Behringer RR, Overbeek PA, O'Neill RJ, Phillips T, Tarulli G, Pask AJ. A long non-coding RNA Leat1 mediates the hormone responsiveness of EfnB2 during male urogenital development. Res Sq. 2023 Jul 03. PMID: 37461443; PMCID: PMC10350214.
      Citations:    
    2. Li L, Long J, Mise K, Galvan DL, Overbeek PA, Tan L, Kumar SV, Chan WK, Lorenzi PL, Chang BH, Danesh FR. PGC1a is required for the renoprotective effect of lncRNA Tug1 in?vivo and links Tug1 with urea cycle metabolites. Cell Rep. 2021 08 10; 36(6):109510. PMID: 34380028; PMCID: PMC8369494.
      Citations:    Fields:    Translation:AnimalsCells
    3. Long J, Galvan DL, Mise K, Kanwar YS, Li L, Poungavrin N, Overbeek PA, Chang BH, Danesh FR. Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1. J Biol Chem. 2020 11 20; 295(47):15840-15852. PMID: 32467232; PMCID: PMC7681008.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    4. Mattiske D, Behringer RR, Overbeek PA, Pask AJ. A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice. Differentiation. 2020 Mar - Apr; 112:1-6. PMID: 31830612.
      Citations: 2     Fields:    Translation:HumansAnimals
    5. Galvan DL, Long J, Green N, Chang BH, Lin JS, Schumacker P, Truong LD, Overbeek P, Danesh FR. Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice. J Clin Invest. 2019 05 07; 129(7):2807-2823. PMID: 31063459; PMCID: PMC6597204.
      Citations: 24     Fields:    Translation:AnimalsCells
    6. Dharmat R, Eblimit A, Robichaux MA, Zhang Z, Nguyen TT, Jung SY, He F, Jain A, Li Y, Qin J, Overbeek P, Roepman R, Mardon G, Wensel TG, Chen R. SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. J Cell Biol. 2018 08 06; 217(8):2851-2865. PMID: 29899041; PMCID: PMC6080925.
      Citations: 17     Fields:    Translation:AnimalsCells
    7. Li J, Lu D, Liu H, Williams BO, Overbeek PA, Lee B, Zheng L, Yang T. Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling. Hum Mol Genet. 2017 08 01; 26(15):2949-2960. PMID: 28486600.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    8. Galvan DL, Badal SS, Long J, Chang BH, Schumacker PT, Overbeek PA, Danesh FR. Real-time in?vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy. Kidney Int. 2017 11; 92(5):1282-1287. PMID: 28754553; PMCID: PMC5656393.
      Citations: 29     Fields:    Translation:AnimalsCells
    9. Wang S, Garcia MD, Lopez AL, Overbeek PA, Larin KV, Larina IV. Dynamic imaging and quantitative analysis of cranial neural tube closure in the mouse embryo using optical coherence tomography. Biomed Opt Express. 2017 Jan 01; 8(1):407-419. PMID: 28101427; PMCID: PMC5231309.
      Citations: 10     
    10. Long J, Badal SS, Ye Z, Wang Y, Ayanga BA, Galvan DL, Green NH, Chang BH, Overbeek PA, Danesh FR. Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy. J Clin Invest. 2016 11 01; 126(11):4205-4218. PMID: 27760051; PMCID: PMC5096930.
      Citations: 157     Fields:    Translation:AnimalsCells
    11. Fu C, Begum K, Jordan PW, He Y, Overbeek PA. Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS One. 2016; 11(8):e0159800. PMID: 27486799; PMCID: PMC4972424.
      Citations: 1     Fields:    Translation:AnimalsCells
    12. Badal SS, Wang Y, Long J, Corcoran DL, Chang BH, Truong LD, Kanwar YS, Overbeek PA, Danesh FR. miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy. Nat Commun. 2016 06 28; 7:12076. PMID: 27350436; PMCID: PMC4931323.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    13. Fu C, Begum K, Overbeek PA. Primary Ovarian Insufficiency Induced by Fanconi Anemia E Mutation in a Mouse Model. PLoS One. 2016; 11(3):e0144285. PMID: 26939056; PMCID: PMC4777492.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    14. Couturier J, Suliburk JW, Brown JM, Luke DJ, Agarwal N, Yu X, Nguyen C, Iyer D, Kozinetz CA, Overbeek PA, Metzker ML, Balasubramanyam A, Lewis DE. Human adipose tissue as a reservoir for memory CD4+ T cells and HIV. AIDS. 2015 Mar 27; 29(6):667-74. PMID: 25849830; PMCID: PMC4389783.
      Citations: 63     Fields:    Translation:HumansCells
    15. Lopez AL, Wang S, Larin KV, Overbeek PA, Larina IV. Live four-dimensional optical coherence tomography reveals embryonic cardiac phenotype in mouse mutant. J Biomed Opt. 2015; 20(9):090501. PMID: 26385422; PMCID: PMC4681392.
      Citations: 13     Fields:    Translation:Animals
    16. Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, Overbeek P, Murray S, Jordan PW. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014 Jul; 10(7):e1004413. PMID: 24992337; PMCID: PMC4081007.
      Citations: 60     Fields:    Translation:AnimalsCells
    17. Caburet S, Arboleda VA, Llano E, Overbeek PA, Barbero JL, Oka K, Harrison W, Vaiman D, Ben-Neriah Z, Garc?a-Tu??n I, Fellous M, Pend?s AM, Veitia RA, Vilain E. Mutant cohesin in premature ovarian failure. N Engl J Med. 2014 Mar 06; 370(10):943-949. PMID: 24597867; PMCID: PMC4068824.
      Citations: 101     Fields:    Translation:HumansAnimals
    18. Moayedi Y, Basch ML, Pacheco NL, Gao SS, Wang R, Harrison W, Xiao N, Oghalai JS, Overbeek PA, Mardon G, Groves AK. The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs. PLoS Genet. 2014 Jan; 10(1):e1004055. PMID: 24391519; PMCID: PMC3879212.
      Citations: 17     Fields:    Translation:AnimalsCells
    19. Lorenzetti D, Poirier C, Zhao M, Overbeek PA, Harrison W, Bishop CE. A transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusion. Mamm Genome. 2014 Apr; 25(3-4):141-8. PMID: 24275887.
      Citations: 36     Fields:    Translation:AnimalsCells
    20. Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A. Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Res. 2013 Dec; 41(22):10199-214. PMID: 24038357; PMCID: PMC3905850.
      Citations: 35     Fields:    Translation:AnimalsCells
    21. Chou WC, Takeo M, Rabbani P, Hu H, Lee W, Chung YR, Carucci J, Overbeek P, Ito M. Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling. Nat Med. 2013 Jul; 19(7):924-9. PMID: 23749232; PMCID: PMC3859297.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    22. Beck TF, Shchelochkov OA, Yu Z, Kim BJ, Zaveri HP, Bishop C, Overbeek PA, Stockton DW, Justice MJ, Scott DA, Hern?ndez-Garc?a A. Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3. PLoS One. 2013; 8(3):e58830. PMID: 23536828; PMCID: PMC3594180.
      Citations: 8     Fields:    Translation:AnimalsCells
    23. Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA. A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012; 7(11):e50634. PMID: 23226340; PMCID: PMC3511458.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    24. Hicks AN, Lorenzetti D, Gilley J, Lu B, Andersson KE, Miligan C, Overbeek PA, Oppenheim R, Bishop CE. Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One. 2012; 7(10):e47869. PMID: 23082226; PMCID: PMC3474723.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    25. Furushima K, Jang CW, Chen DW, Xiao N, Overbeek PA, Behringer RR. Insertional mutagenesis by a hybrid piggyBac and sleeping beauty transposon in the rat. Genetics. 2012 Dec; 192(4):1235-48. PMID: 23023007; PMCID: PMC3512136.
      Citations: 16     Fields:    Translation:AnimalsCells
    26. Larina IV, Syed SH, Sudheendran N, Overbeek PA, Dickinson ME, Larin KV. Optical coherence tomography for live phenotypic analysis of embryonic ocular structures in mouse models. J Biomed Opt. 2012 Aug; 17(8):081410-1. PMID: 23224171; PMCID: PMC3397804.
      Citations: 12     Fields:    Translation:HumansAnimals
    27. Wadhwa L, Bond WS, Perlaky L, Overbeek PA, Hurwitz MY, Hurwitz RL, Ch?vez-Barrios P. Embryonic retinal tumors in SV40 T-Ag transgenic mice contain CD133+ tumor-initiating cells. Invest Ophthalmol Vis Sci. 2012 Jun 08; 53(7):3454-62. PMID: 22562503; PMCID: PMC4022423.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    28. Somma G, Alger HM, McGuire RM, Kretlow JD, Ruiz FR, Yatsenko SA, Stankiewicz P, Harrison W, Funk E, Bergamaschi A, Oghalai JS, Mikos AG, Overbeek PA, Pereira FA. Head bobber: an insertional mutation causes inner ear defects, hyperactive circling, and deafness. J Assoc Res Otolaryngol. 2012 Jun; 13(3):335-49. PMID: 22383091; PMCID: PMC3346896.
      Citations: 4     Fields:    Translation:AnimalsCells
    29. Wang W, Wang Y, Long J, Wang J, Haudek SB, Overbeek P, Chang BH, Schumacker PT, Danesh FR. Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab. 2012 Feb 08; 15(2):186-200. PMID: 22326220; PMCID: PMC3278719.
      Citations: 217     Fields:    Translation:AnimalsCells
    30. Wang B, Harrison W, Overbeek PA, Zheng H. Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct; 138(20):4487-97. PMID: 21937600; PMCID: PMC3177318.
      Citations: 21     Fields:    Translation:AnimalsCells
    31. Reneker LW, Chen H, Overbeek PA. Activation of unfolded protein response in transgenic mouse lenses. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2100-8. PMID: 21310900; PMCID: PMC3080171.
      Citations: 12     Fields:    Translation:AnimalsCells
    32. Hamilton SM, Spencer CM, Harrison WR, Yuva-Paylor LA, Graham DF, Daza RA, Hevner RF, Overbeek PA, Paylor R. Multiple autism-like behaviors in a novel transgenic mouse model. Behav Brain Res. 2011 Mar 17; 218(1):29-41. PMID: 21093492; PMCID: PMC3022332.
      Citations: 26     Fields:    Translation:Animals
    33. Sales KU, Masedunskas A, Bey AL, Rasmussen AL, Weigert R, List K, Szabo R, Overbeek PA, Bugge TH. Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome. Nat Genet. 2010 Aug; 42(8):676-83. PMID: 20657595; PMCID: PMC3081165.
      Citations: 40     Fields:    Translation:HumansAnimals
    34. Wang J, Wang Y, Long J, Chang BH, Wilson MH, Overbeek P, Danesh FR. Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo. Genesis. 2010 Jul; 48(7):446-51. PMID: 20641128; PMCID: PMC3014324.
      Citations: 15     Fields:    Translation:AnimalsCells
    35. Li W, Puertollano R, Bonifacino JS, Overbeek PA, Everett ET. Disruption of the murine Ap2?1 gene causes nonsyndromic cleft palate. Cleft Palate Craniofac J. 2010 Nov; 47(6):566-73. PMID: 20500056; PMCID: PMC3691559.
      Citations: 13     Fields:    Translation:Animals
    36. Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V. Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010 Jan 27; 10:13. PMID: 20105280; PMCID: PMC2828409.
      Citations: 14     Fields:    Translation:AnimalsCells
    37. Reneker LW, Bloch A, Xie L, Overbeek PA, Ash JD. Induction of corneal myofibroblasts by lens-derived transforming growth factor beta1 (TGFbeta1): a transgenic mouse model. Brain Res Bull. 2010 Feb 15; 81(2-3):287-96. PMID: 19897021; PMCID: PMC2814984.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    38. Sharov AA, Mardaryev AN, Sharova TY, Grachtchouk M, Atoyan R, Byers HR, Seykora JT, Overbeek P, Dlugosz A, Botchkarev VA. Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways. Am J Pathol. 2009 Sep; 175(3):1303-14. PMID: 19700758; PMCID: PMC2731148.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    39. Zhang Y, Tomann P, Andl T, Gallant NM, Huelsken J, Jerchow B, Birchmeier W, Paus R, Piccolo S, Mikkola ML, Morrisey EE, Overbeek PA, Scheidereit C, Millar SE, Schmidt-Ullrich R. Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell. 2009 Jul; 17(1):49-61. PMID: 19619491; PMCID: PMC2859042.
      Citations: 155     Fields:    Translation:AnimalsCells
    40. Davis N, Yoffe C, Raviv S, Antes R, Berger J, Holzmann S, Stoykova A, Overbeek PA, Tamm ER, Ashery-Padan R. Pax6 dosage requirements in iris and ciliary body differentiation. Dev Biol. 2009 Sep 01; 333(1):132-42. PMID: 19563798.
      Citations: 24     Fields:    Translation:AnimalsCells
    41. Heath J, Langton AK, Hammond NL, Overbeek PA, Dixon MJ, Headon DJ. Hair follicles are required for optimal growth during lateral skin expansion. J Invest Dermatol. 2009 Oct; 129(10):2358-64. PMID: 19387480.
      Citations: 9     Fields:    Translation:AnimalsCells
    42. Lavail MM, Nishikawa S, Duncan JL, Yang H, Matthes MT, Yasumura D, Vollrath D, Overbeek PA, Ash JD, Robinson ML. Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations. J Comp Neurol. 2008 Dec 20; 511(6):724-35. PMID: 18925574; PMCID: PMC2702994.
      Citations: 9     Fields:    Translation:AnimalsCells
    43. Boswell BA, Overbeek PA, Musil LS. Essential role of BMPs in FGF-induced secondary lens fiber differentiation. Dev Biol. 2008 Dec 15; 324(2):202-12. PMID: 18848538; PMCID: PMC2853743.
      Citations: 33     Fields:    Translation:AnimalsCells
    44. Zhang Y, Burgess D, Overbeek PA, Govindarajan V. Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 01; 323(1):53-63. PMID: 18778700; PMCID: PMC2652847.
      Citations: 2     Fields:    Translation:Animals
    45. Plas DT, Dhande OS, Lopez JE, Murali D, Thaller C, Henkemeyer M, Furuta Y, Overbeek P, Crair MC. Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse. J Neurosci. 2008 Jul 09; 28(28):7057-67. PMID: 18614674; PMCID: PMC2667968.
      Citations: 20     Fields:    Translation:HumansAnimals
    46. Chen Q, Liang D, Overbeek PA. Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice. Mol Vis. 2008 Mar 25; 14:602-14. PMID: 18385796; PMCID: PMC2275213.
      Citations: 5     Fields:    Translation:HumansAnimals
    47. Lu B, Poirier C, Gaspar T, Gratzke C, Harrison W, Busija D, Matzuk MM, Andersson KE, Overbeek PA, Bishop CE. A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Biol Reprod. 2008 Apr; 78(4):601-10. PMID: 18094351.
      Citations: 47     Fields:    Translation:AnimalsCells
    48. Zhang Y, Overbeek PA, Govindarajan V. Perinatal ablation of the mouse lens causes multiple anterior chamber defects. Mol Vis. 2007 Dec 18; 13:2289-300. PMID: 18199970.
      Citations: 13     Fields:    Translation:AnimalsCells
    49. Lu B, Geurts AM, Poirier C, Petit DC, Harrison W, Overbeek PA, Bishop CE. Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mamm Genome. 2007 May; 18(5):338-46. PMID: 17557177.
      Citations: 43     Fields:    Translation:AnimalsCells
    50. Xie L, Chen H, Overbeek PA, Reneker LW. Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens. Mol Vis. 2007 Mar 26; 13:397-407. PMID: 17417601; PMCID: PMC2642934.
      Citations: 13     Fields:    Translation:AnimalsCells
    51. Xiao W, Liu W, Li Z, Liang D, Li L, White LD, Fox DA, Overbeek PA, Chen Q. Gene expression profiling in embryonic mouse lenses. Mol Vis. 2006 Dec 26; 12:1692-8. PMID: 17213798.
      Citations: 8     Fields:    Translation:AnimalsCells
    52. Banh A, Deschamps PA, Gauldie J, Overbeek PA, Sivak JG, West-Mays JA. Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3450-60. PMID: 16877415; PMCID: PMC2811063.
      Citations: 33     Fields:    Translation:Animals
    53. Xie L, Overbeek PA, Reneker LW. Ras signaling is essential for lens cell proliferation and lens growth during development. Dev Biol. 2006 Oct 15; 298(2):403-14. PMID: 16889766.
      Citations: 17     Fields:    Translation:AnimalsCells
    54. Mou C, Jackson B, Schneider P, Overbeek PA, Headon DJ. Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9075-80. PMID: 16769906; PMCID: PMC1482568.
      Citations: 81     Fields:    Translation:AnimalsCells
    55. Govindarajan V, Overbeek PA. FGF9 can induce endochondral ossification in cranial mesenchyme. BMC Dev Biol. 2006 Feb 20; 6:7. PMID: 16504022; PMCID: PMC1395304.
      Citations: 27     Fields:    Translation:AnimalsCells
    56. Govindarajan V, Harrison WR, Xiao N, Liang D, Overbeek PA. Intracorneal positioning of the lens in Pax6-GAL4/VP16 transgenic mice. Mol Vis. 2005 Oct 26; 11:876-86. PMID: 16270027.
      Citations: 7     Fields:    Translation:AnimalsCells
    57. Graham DR, Overbeek PA, Ash JD. Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation. Invest Ophthalmol Vis Sci. 2005 Jul; 46(7):2601-10. PMID: 15980254.
      Citations: 13     Fields:    Translation:AnimalsCells
    58. Reneker LW, Chen Q, Bloch A, Xie L, Schuster G, Overbeek PA. Chick delta1-crystallin enhancer influences mouse alphaA-crystallin promoter activity in transgenic mice. Invest Ophthalmol Vis Sci. 2004 Nov; 45(11):4083-90. PMID: 15505059.
      Citations: 19     Fields:    Translation:AnimalsCells
    59. Yang T, Liang D, Koch PJ, Hohl D, Kheradmand F, Overbeek PA. Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice. Genes Dev. 2004 Oct 01; 18(19):2354-8. PMID: 15466487; PMCID: PMC522985.
      Citations: 25     Fields:    Translation:AnimalsCells
    60. Phillips CL, Miller KJ, Filson AJ, Clendenon JL, Cook GW, Dunn KW, Overbeek PA, Gattone VH, Bacallao RL, N?rnberger J. Renal cysts of inv/inv mice resemble early infantile nephronophthisis. J Am Soc Nephrol. 2004 Jul; 15(7):1744-55. PMID: 15213262.
      Citations: 30     Fields:    Translation:Animals
    61. Zhao H, Yang Y, Rizo CM, Overbeek PA, Robinson ML. Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice. Invest Ophthalmol Vis Sci. 2004 Jun; 45(6):1930-9. PMID: 15161860.
      Citations: 69     Fields:    Translation:AnimalsCells
    62. Qin Y, Kong LK, Poirier C, Truong C, Overbeek PA, Bishop CE. Long-range activation of Sox9 in Odd Sex (Ods) mice. Hum Mol Genet. 2004 Jun 15; 13(12):1213-8. PMID: 15115764.
      Citations: 42     Fields:    Translation:AnimalsCells
    63. Tucker AS, Headon DJ, Courtney JM, Overbeek P, Sharpe PT. The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development. Dev Biol. 2004 Apr 01; 268(1):185-94. PMID: 15031115.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    64. Chen Q, Liang D, Fromm LD, Overbeek PA. Inhibition of lens fiber cell morphogenesis by expression of a mutant SV40 large T antigen that binds CREB-binding protein/p300 but not pRb. J Biol Chem. 2004 Apr 23; 279(17):17667-73. PMID: 14742445.
      Citations: 9     Fields:    Translation:AnimalsCells
    65. Reneker LW, Xie L, Xu L, Govindarajan V, Overbeek PA. Activated Ras induces lens epithelial cell hyperplasia but not premature differentiation. Int J Dev Biol. 2004; 48(8-9):879-88. PMID: 15558479.
      Citations: 10     Fields:    Translation:AnimalsCells
    66. Chen Q, Liang D, Yang T, Leone G, Overbeek PA. Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice. Dev Neurosci. 2004; 26(5-6):435-45. PMID: 15855772.
      Citations: 10     Fields:    Translation:HumansAnimals
    67. Zhao S, Chen Q, Hung FC, Overbeek PA. BMP signaling is required for development of the ciliary body. Development. 2002 Oct; 129(19):4435-42. PMID: 12223402.
      Citations: 56     Fields:    Translation:AnimalsCells
    68. Pilon N, Boyer A, Behdjani R, Overbeek PA, Viger R, Lussier J, Silversides DW, Daneau I. The porcine SRY promoter is transactivated within a male genital ridge environment. Genesis. 2002 Aug; 33(4):170-80. PMID: 12203914.
      Citations: 3     Fields:    Translation:AnimalsCells
    69. Xu L, Overbeek PA, Reneker LW. Systematic analysis of E-, N- and P-cadherin expression in mouse eye development. Exp Eye Res. 2002 Jun; 74(6):753-60. PMID: 12126948.
      Citations: 67     Fields:    Translation:Animals
    70. Chen Q, Dowhan DH, Liang D, Moore DD, Overbeek PA. CREB-binding protein/p300 co-activation of crystallin gene expression. J Biol Chem. 2002 Jul 05; 277(27):24081-9. PMID: 11943779.
      Citations: 43     Fields:    Translation:AnimalsCells
    71. Cunningham D, Xiao Q, Chatterjee A, Sulik K, Juriloff D, Elder F, Harrison W, Schuster G, Overbeek PA, Herman GE. exma: an X-linked insertional mutation that disrupts forebrain and eye development. Mamm Genome. 2002 Apr; 13(4):179-85. PMID: 11956759.
      Citations: 4     Fields:    Translation:AnimalsCells
    72. Chen Q, Ash JD, Branton P, Fromm L, Overbeek PA. Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice. Oncogene. 2002 Feb 07; 21(7):1028-37. PMID: 11850820.
      Citations: 11     Fields:    Translation:AnimalsCells
    73. Lovicu FJ, Schulz MW, Hales AM, Vincent LN, Overbeek PA, Chamberlain CG, McAvoy JW. TGFbeta induces morphological and molecular changes similar to human anterior subcapsular cataract. Br J Ophthalmol. 2002 Feb; 86(2):220-6. PMID: 11815351; PMCID: PMC1771017.
      Citations: 70     Fields:    Translation:Animals
    74. Hung FC, Zhao S, Chen Q, Overbeek PA. Retinal ablation and altered lens differentiation induced by ocular overexpression of BMP7. Vision Res. 2002 Feb; 42(4):427-38. PMID: 11853758.
      Citations: 16     Fields:    Translation:Animals
    75. Zhao S, Overbeek PA. Regulation of choroid development by the retinal pigment epithelium. Mol Vis. 2001 Dec 02; 7:277-82. PMID: 11740467.
      Citations: 27     Fields:    Translation:AnimalsCells
    76. Zhao S, Hung FC, Colvin JS, White A, Dai W, Lovicu FJ, Ornitz DM, Overbeek PA. Patterning the optic neuroepithelium by FGF signaling and Ras activation. Development. 2001 Dec; 128(24):5051-60. PMID: 11748141.
      Citations: 40     Fields:    Translation:AnimalsCells
    77. Headon DJ, Emmal SA, Ferguson BM, Tucker AS, Justice MJ, Sharpe PT, Zonana J, Overbeek PA. Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature. 2001 Dec 20-27; 414(6866):913-6. PMID: 11780064.
      Citations: 103     Fields:    Translation:HumansAnimalsCells
    78. de Iongh RU, Lovicu FJ, Overbeek PA, Schneider MD, Joya J, Hardeman ED, McAvoy JW. Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation. Development. 2001 Oct; 128(20):3995-4010. PMID: 11641223.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    79. Zhao S, Overbeek PA. Elevated TGFbeta signaling inhibits ocular vascular development. Dev Biol. 2001 Sep 01; 237(1):45-53. PMID: 11518504.
      Citations: 13     Fields:    Translation:Animals
    80. Oh H, Taffet GE, Youker KA, Entman ML, Overbeek PA, Michael LH, Schneider MD. Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10308-13. PMID: 11517337; PMCID: PMC56957.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    81. Govindarajan V, Overbeek PA. Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation. Development. 2001 May; 128(9):1617-27. PMID: 11290300.
      Citations: 32     Fields:    Translation:AnimalsCells
    82. Overbeek PA, Gorlov IP, Sutherland RW, Houston JB, Harrison WR, Boettger-Tong HL, Bishop CE, Agoulnik AI. A transgenic insertion causing cryptorchidism in mice. Genesis. 2001 May; 30(1):26-35. PMID: 11353515.
      Citations: 51     Fields:    Translation:AnimalsCells
    83. Smahi A, Bessia C, Geissmann F, Feinberg J, Durandy A, Bodemer C, Kenwrick S, Dupuis-Girod S, Blanche S, Wood P, Rabia SH, Headon DJ, Overbeek PA, Le Deist F, Holland SM, Belani K, Kumararatne DS, Fischer A, Shapiro R, Conley ME, Reimund E, Kalhoff H, Abinun M, Munnich A, Courtois G, Casanova JL, D?ffinger R, Isra?l A. X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling. Nat Genet. 2001 Mar; 27(3):277-85. PMID: 11242109.
      Citations: 238     Fields:    Translation:HumansCells
    84. Shirke S, Faber SC, Hallem E, Makarenkova HP, Robinson ML, Overbeek PA, Lang RA. Misexpression of IGF-I in the mouse lens expands the transitional zone and perturbs lens polarization. Mech Dev. 2001 Mar; 101(1-2):167-74. PMID: 11231069.
      Citations: 17     Fields:    Translation:AnimalsCells
    85. Bishop CE, Whitworth DJ, Qin Y, Agoulnik AI, Agoulnik IU, Harrison WR, Behringer RR, Overbeek PA. A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse. Nat Genet. 2000 Dec; 26(4):490-4. PMID: 11101852.
      Citations: 91     Fields:    Translation:AnimalsCells
    86. Chen Q, Hung FC, Fromm L, Overbeek PA. Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4223-31. PMID: 11095619.
      Citations: 22     Fields:    Translation:AnimalsCells
    87. Tucker AS, Headon DJ, Schneider P, Ferguson BM, Overbeek P, Tschopp J, Sharpe PT. Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis. Development. 2000 Nov; 127(21):4691-700. PMID: 11023871.
      Citations: 56     Fields:    Translation:Animals
    88. Govindarajan V, Ito M, Makarenkova HP, Lang RA, Overbeek PA. Endogenous and ectopic gland induction by FGF-10. Dev Biol. 2000 Sep 01; 225(1):188-200. PMID: 10964474.
      Citations: 41     Fields:    Translation:Animals
    89. Ash JD, Overbeek PA. Lens-specific VEGF-A expression induces angioblast migration and proliferation and stimulates angiogenic remodeling. Dev Biol. 2000 Jul 15; 223(2):383-98. PMID: 10882523.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    90. Makarenkova HP, Ito M, Govindarajan V, Faber SC, Sun L, McMahon G, Overbeek PA, Lang RA. FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development. Development. 2000 Jun; 127(12):2563-72. PMID: 10821755.
      Citations: 85     Fields:    Translation:AnimalsCells
    91. Passier R, Zeng H, Frey N, Naya FJ, Nicol RL, McKinsey TA, Overbeek P, Richardson JA, Grant SR, Olson EN. CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. J Clin Invest. 2000 May; 105(10):1395-406. PMID: 10811847; PMCID: PMC315462.
      Citations: 180     Fields:    Translation:HumansAnimalsCells
    92. Zhang D, Gaussin V, Taffet GE, Belaguli NS, Yamada M, Schwartz RJ, Michael LH, Overbeek PA, Schneider MD. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat Med. 2000 May; 6(5):556-63. PMID: 10802712.
      Citations: 120     Fields:    Translation:AnimalsCells
    93. Reneker LW, Silversides DW, Xu L, Overbeek PA. Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis. Development. 2000 Feb; 127(3):533-42. PMID: 10631174.
      Citations: 34     Fields:    Translation:HumansAnimals
    94. Ring BZ, Cordes SP, Overbeek PA, Barsh GS. Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development. 2000 Jan; 127(2):307-17. PMID: 10603348.
      Citations: 97     Fields:    Translation:AnimalsCells
    95. Zhao S, Overbeek PA. Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues. Dev Biol. 1999 Dec 01; 216(1):154-63. PMID: 10588869.
      Citations: 22     Fields:    Translation:AnimalsCells
    96. Lu W, Phillips CL, Killen PD, Hlaing T, Harrison WR, Elder FF, Miner JH, Overbeek PA, Meisler MH. Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome. Genomics. 1999 Oct 15; 61(2):113-24. PMID: 10534397.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    97. Lovicu FJ, Kao WW, Overbeek PA. Ectopic gland induction by lens-specific expression of keratinocyte growth factor (FGF-7) in transgenic mice. Mech Dev. 1999 Oct; 88(1):43-53. PMID: 10525187.
      Citations: 11     Fields:    Translation:HumansAnimals
    98. Schneider A, Mijalski T, Schlange T, Dai W, Overbeek P, Arnold HH, Brand T. The homeobox gene NKX3.2 is a target of left-right signalling and is expressed on opposite sides in chick and mouse embryos. Curr Biol. 1999 Aug 26; 9(16):911-4. PMID: 10469600.
      Citations: 14     Fields:    Translation:AnimalsCells
    99. Monreal AW, Ferguson BM, Headon DJ, Street SL, Overbeek PA, Zonana J. Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Nat Genet. 1999 Aug; 22(4):366-9. PMID: 10431241.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    100. Mazziotti MV, Willis LK, Heuckeroth RO, LaRegina MC, Swanson PE, Overbeek PA, Perlmutter DH. Anomalous development of the hepatobiliary system in the Inv mouse. Hepatology. 1999 Aug; 30(2):372-8. PMID: 10421642.
      Citations: 17     Fields:    Translation:Animals
    101. Headon DJ, Overbeek PA. Involvement of a novel Tnf receptor homologue in hair follicle induction. Nat Genet. 1999 Aug; 22(4):370-4. PMID: 10431242.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    102. Fei Y, Matragoon S, Smith SB, Overbeek PA, Chen S, Zack DJ, Liou GI. Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: the cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo. J Biochem. 1999 Jun; 125(6):1189-99. PMID: 10348924.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    103. Naya FJ, Wu C, Richardson JA, Overbeek P, Olson EN. Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene. Development. 1999 May; 126(10):2045-52. PMID: 10207130.
      Citations: 71     Fields:    Translation:AnimalsCells
    104. Sutherland ML, Williams SH, Abedi R, Overbeek PA, Pfaffinger PJ, Noebels JL. Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):2451-5. PMID: 10051663; PMCID: PMC26805.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    105. Majumder K, Shawlot W, Schuster G, Harrison W, Elder FF, Overbeek PA. YAC rescue of downless locus mutations in mice. Mamm Genome. 1998 Nov; 9(11):863-8. PMID: 9799834.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    106. Morgan D, Turnpenny L, Goodship J, Dai W, Majumder K, Matthews L, Gardner A, Schuster G, Vien L, Harrison W, Elder FF, Penman-Splitt M, Overbeek P, Strachan T. Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse. Nat Genet. 1998 Oct; 20(2):149-56. PMID: 9771707.
      Citations: 59     Fields:    Translation:AnimalsCells
    107. Mochizuki T, Saijoh Y, Tsuchiya K, Shirayoshi Y, Takai S, Taya C, Yonekawa H, Yamada K, Nihei H, Nakatsuji N, Overbeek PA, Hamada H, Yokoyama T. Cloning of inv, a gene that controls left/right asymmetry and kidney development. Nature. 1998 Sep 10; 395(6698):177-81. PMID: 9744276.
      Citations: 67     Fields:    Translation:AnimalsCells
    108. Lovicu FJ, Overbeek PA. Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice. Development. 1998 Sep; 125(17):3365-77. PMID: 9693140.
      Citations: 56     Fields:    Translation:AnimalsCells
    109. Charng MJ, Frenkel PA, Lin Q, Yamada M, Schwartz RJ, Olson EN, Overbeek P, Schneider MD, Yumada M. A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice. Dev Biol. 1998 Jul 01; 199(1):72-9. PMID: 9676193.
      Citations: 13     Fields:    Translation:AnimalsCells
    110. Robinson ML, Ohtaka-Maruyama C, Chan CC, Jamieson S, Dickson C, Overbeek PA, Chepelinsky AB. Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice. Dev Biol. 1998 Jun 01; 198(1):13-31. PMID: 9640329.
      Citations: 32     Fields:    Translation:Animals
    111. Thomas T, Yamagishi H, Overbeek PA, Olson EN, Srivastava D. The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Dev Biol. 1998 Apr 15; 196(2):228-36. PMID: 9576835.
      Citations: 46     Fields:    Translation:AnimalsCells
    112. Srinivasan Y, Lovicu FJ, Overbeek PA. Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J Clin Invest. 1998 Feb 01; 101(3):625-34. PMID: 9449696; PMCID: PMC508606.
      Citations: 57     Fields:    Translation:HumansAnimals
    113. Esther CR, Semeniuk D, Marino EM, Zhou Y, Overbeek PA, Bernstein KE. Expression of testis angiotensin-converting enzyme is mediated by a cyclic AMP responsive element. Lab Invest. 1997 Nov; 77(5):483-8. PMID: 9389791.
      Citations: 5     Fields:    Translation:AnimalsCells
    114. Li L, Liu Z, Mercer B, Overbeek P, Olson EN. Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cells. Dev Biol. 1997 Jul 15; 187(2):311-21. PMID: 9242426.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    115. Agah R, Frenkel PA, French BA, Michael LH, Overbeek PA, Schneider MD. Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest. 1997 Jul 01; 100(1):169-79. PMID: 9202069; PMCID: PMC508177.
      Citations: 314     Fields:    Translation:HumansAnimalsCells
    116. Overbeek PA. Right and left go dHAND and eHAND. Nat Genet. 1997 Jun; 16(2):119-21. PMID: 9171820.
      Citations:    Fields:    Translation:Animals
    117. Fromm L, Overbeek PA. Inhibition of cell death by lens-specific overexpression of bcl-2 in transgenic mice. Dev Genet. 1997; 20(3):276-87. PMID: 9216067.
      Citations: 13     Fields:    Translation:HumansAnimals
    118. Reneker LW, Overbeek PA. Lens-specific expression of PDGF-A alters lens growth and development. Dev Biol. 1996 Dec 15; 180(2):554-65. PMID: 8954727.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    119. Reneker LW, Overbeek PA. Lens-specific expression of PDGF-A in transgenic mice results in retinal astrocytic hamartomas. Invest Ophthalmol Vis Sci. 1996 Nov; 37(12):2455-66. PMID: 8933762.
      Citations: 17     Fields:    Translation:AnimalsCells
    120. Robinson ML, Overbeek PA. Differential expression of alpha A- and alpha B-crystallin during murine ocular development. Invest Ophthalmol Vis Sci. 1996 Oct; 37(11):2276-84. PMID: 8843924.
      Citations: 51     Fields:    Translation:AnimalsCells
    121. Zhou Y, Overbeek PA, Bernstein KE. Tissue specific expression of testis angiotensin converting enzyme is not determined by the -32 nonconsensus TATA motif. Biochem Biophys Res Commun. 1996 Jun 05; 223(1):48-53. PMID: 8660377.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    122. Lowe LA, Supp DM, Sampath K, Yokoyama T, Wright CV, Potter SS, Overbeek P, Kuehn MR. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature. 1996 May 09; 381(6578):158-61. PMID: 8610013.
      Citations: 88     Fields:    Translation:Animals
    123. Marcus DM, Lasudry JG, Carpenter JL, Windle J, Howes KA, al-Ubaidi MR, Baehr W, Overbeek PA, Font RL, Albert DM. Trilateral tumors in four different lines of transgenic mice expressing SV40 T-antigen. Invest Ophthalmol Vis Sci. 1996 Feb; 37(2):392-6. PMID: 8603844.
      Citations: 8     Fields:    Translation:Animals
    124. Fromm L, Overbeek PA. Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein. Oncogene. 1996 Jan 04; 12(1):69-75. PMID: 8552401.
      Citations: 10     Fields:    Translation:AnimalsCells
    125. Robinson ML, MacMillan-Crow LA, Thompson JA, Overbeek PA. Expression of a truncated FGF receptor results in defective lens development in transgenic mice. Development. 1995 Dec; 121(12):3959-67. PMID: 8575296.
      Citations: 36     Fields:    Translation:AnimalsCells
    126. Reneker LW, Silversides DW, Patel K, Overbeek PA. TGF alpha can act as a chemoattractant to perioptic mesenchymal cells in developing mouse eyes. Development. 1995 Jun; 121(6):1669-80. PMID: 7600984.
      Citations: 15     Fields:    Translation:AnimalsCells
    127. Cho YJ, Chema D, Moskow JJ, Cho M, Schroeder WT, Overbeek P, Buchberg AM, Duvic M. Epidermal surface antigen (MS17S1) is highly conserved between mouse and human. Genomics. 1995 May 20; 27(2):251-8. PMID: 7557989.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    128. Schaffner DL, Barrios R, Shaker MR, Rajagopalan S, Huang SL, Tindall DJ, Young CY, Overbeek PA, Lebovitz RM, Lieberman MW. Transgenic mice carrying a PSArasT24 hybrid gene develop salivary gland and gastrointestinal tract neoplasms. Lab Invest. 1995 Mar; 72(3):283-90. PMID: 7534850.
      Citations: 5     Fields:    Translation:AnimalsCells
    129. Morgenbesser SD, Schreiber-Agus N, Bidder M, Mahon KA, Overbeek PA, Horner J, DePinho RA. Contrasting roles for c-Myc and L-Myc in the regulation of cellular growth and differentiation in vivo. EMBO J. 1995 Feb 15; 14(4):743-56. PMID: 7882978; PMCID: PMC398140.
      Citations: 19     Fields:    Translation:AnimalsCells
    130. Robinson ML, Overbeek PA, Verran DJ, Grizzle WE, Stockard CR, Friesel R, Maciag T, Thompson JA. Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice. Development. 1995 Feb; 121(2):505-14. PMID: 7539358.
      Citations: 60     Fields:    Translation:AnimalsCells
    131. Ribar TJ, Epstein PN, Overbeek PA, Means AR. Targeted overexpression of an inactive calmodulin that binds Ca2+ to the mouse pancreatic beta-cell results in impaired secretion and chronic hyperglycemia. Endocrinology. 1995 Jan; 136(1):106-15. PMID: 7828519.
      Citations: 6     Fields:    Translation:Animals
    132. Fromm L, Shawlot W, Gunning K, Butel JS, Overbeek PA. The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice. Mol Cell Biol. 1994 Oct; 14(10):6743-54. PMID: 7935393; PMCID: PMC359205.
      Citations: 30     Fields:    Translation:AnimalsCells
    133. Liou GI, Matragoon S, Overbeek PA, Fei Y. Identification of a retina-specific footprint within the retina-specific regulatory region of the human interphotoreceptor retinoid-binding protein gene. Biochem Biophys Res Commun. 1994 Sep 30; 203(3):1875-81. PMID: 7945340.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    134. Geske RS, Xue JJ, Hsu CY, Overbeek PA, Patel PI, Rinc?n-Limas DE. 5'-flanking sequences of the human HPRT gene direct neuronal expression in the brain of transgenic mice. J Neurosci Res. 1994 Jun 15; 38(3):259-67. PMID: 7523686.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    135. Russell LD, Ying L, Overbeek PA. Insertional mutation that causes acrosomal hypo-development: its relationship to sperm head shaping. Anat Rec. 1994 Apr; 238(4):437-53. PMID: 8192241.
      Citations: 3     Fields:    Translation:AnimalsCells
    136. Winston JH, Hong L, Akroyd S, Hanten G, Waymire K, Overbeek P, Kellems RE. Diverse genetic regulatory elements are required to direct the proper tissue-specific and developmental expression of the murine adenosine deaminase gene. Adv Exp Med Biol. 1994; 370:579-84. PMID: 7660973.
      Citations:    Fields:    Translation:AnimalsCells
    137. Schaffner DL, Barrios R, Overbeek PA, Lebovitz RM, Lieberman MW, Ch?vez-Barrios P. Expression of the rasT24 oncogene in the ciliary body pigment epithelium and retinal pigment epithelium results in hyperplasia, adenoma, and adenocarcinoma. Am J Pathol. 1993 Jul; 143(1):20-8. PMID: 8100399; PMCID: PMC1886968.
      Citations: 1     Fields:    Translation:AnimalsCells
    138. Yokoyama T, Copeland NG, Jenkins NA, Montgomery CA, Elder FF, Overbeek PA. Reversal of left-right asymmetry: a situs inversus mutation. Science. 1993 Apr 30; 260(5108):679-82. PMID: 8480178.
      Citations: 73     Fields:    Translation:Animals
    139. Schaffner DL, Barrios R, Massey C, Ou CN, Rajagopalan S, Aguilar-Cordova E, Lebovitz RM, Overbeek PA, Lieberman MW, Ba?ez EI. Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys. Am J Pathol. 1993 Apr; 142(4):1051-60. PMID: 8097368; PMCID: PMC1886875.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    140. Howard T, Balogh R, Overbeek P, Bernstein KE. Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element. Mol Cell Biol. 1993 Jan; 13(1):18-27. PMID: 8380220; PMCID: PMC358880.
      Citations: 25     Fields:    Translation:AnimalsCells
    141. Epstein PN, Boschero AC, Atwater I, Cai X, Overbeek PA. Expression of yeast hexokinase in pancreatic beta cells of transgenic mice reduces blood glucose, enhances insulin secretion, and decreases diabetes. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12038-42. PMID: 1465437; PMCID: PMC50693.
      Citations: 22     Fields:    Translation:AnimalsCells
    142. al-Ubaidi MR, Font RL, Quiambao AB, Keener MJ, Liou GI, Overbeek PA, Baehr W. Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter. J Cell Biol. 1992 Dec; 119(6):1681-7. PMID: 1334963; PMCID: PMC2289740.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    143. Yokoyama T, Liou GI, Caldwell RB, Overbeek PA. Photoreceptor-specific activity of the human interphotoreceptor retinoid-binding protein (IRBP) promoter in transgenic mice. Exp Eye Res. 1992 Aug; 55(2):225-33. PMID: 1426058.
      Citations: 11     Fields:    Translation:AnimalsCells
    144. Winston JH, Hanten GR, Overbeek PA, Kellems RE. 5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice. J Biol Chem. 1992 Jul 05; 267(19):13472-9. PMID: 1618849.
      Citations: 5     Fields:    Translation:AnimalsCells
    145. al-Ubaidi MR, Hollyfield JG, Overbeek PA, Baehr W. Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice. Proc Natl Acad Sci U S A. 1992 Feb 15; 89(4):1194-8. PMID: 1311085; PMCID: PMC48415.
      Citations: 53     Fields:    Translation:AnimalsCells
    146. Overbeek PA, Aguilar-Cordova E, Hanten G, Schaffner DL, Patel P, Lebovitz RM, Lieberman MW. Coinjection strategy for visual identification of transgenic mice. Transgenic Res. 1991 Dec; 1(1):31-7. PMID: 1844573.
      Citations: 26     Fields:    Translation:AnimalsCells
    147. Liou GI, Matragoon S, Yang J, Geng L, Overbeek PA, Ma DP. Retina-specific expression from the IRBP promoter in transgenic mice is conferred by 212 bp of the 5'-flanking region. Biochem Biophys Res Commun. 1991 Nov 27; 181(1):159-65. PMID: 1958183.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    148. MacGregor GR, Overbeek PA. Use of a simplified single-site PCR to facilitate cloning of genomic DNA sequences flanking a transgene integration site. PCR Methods Appl. 1991 Nov; 1(2):129-35. PMID: 1842930.
      Citations: 2     Fields:    Translation:AnimalsCells
    149. Fletcher FA, Moore KA, Ashkenazi M, De Vries P, Overbeek PA, Williams DE, Belmont JW. Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo. J Exp Med. 1991 Oct 01; 174(4):837-45. PMID: 1655947; PMCID: PMC2118965.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    150. Russell LD, Hikim AP, Overbeek PA, MacGregor GR. Testis structure in the sys (symplastic spermatids) mouse. Am J Anat. 1991 Oct; 192(2):169-82. PMID: 1759682.
      Citations: 4     Fields:    Translation:AnimalsCells
    151. Langford KG, Shai SY, Howard TE, Kovac MJ, Overbeek PA, Bernstein KE. Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme. J Biol Chem. 1991 Aug 25; 266(24):15559-62. PMID: 1651914.
      Citations: 35     Fields:    Translation:AnimalsCells
    152. Eva A, Graziani G, Zannini M, Merin LM, Khillan JS, Overbeek PA. Dominant dysplasia of the lens in transgenic mice expressing the dbl oncogene. New Biol. 1991 Feb; 3(2):158-68. PMID: 2065011.
      Citations: 6     Fields:    Translation:Animals
    153. Yokoyama T, Silversides DW, Waymire KG, Kwon BS, Takeuchi T, Overbeek PA. Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice. Nucleic Acids Res. 1990 Dec 25; 18(24):7293-8. PMID: 2124349; PMCID: PMC332865.
      Citations: 74     Fields:    Translation:AnimalsCells
    154. MacGregor GR, Russell LD, Van Beek ME, Hanten GR, Kovac MJ, Kozak CA, Meistrich ML, Overbeek PA. Symplastic spermatids (sys): a recessive insertional mutation in mice causing a defect in spermatogenesis. Proc Natl Acad Sci U S A. 1990 Jul; 87(13):5016-20. PMID: 2164218; PMCID: PMC54252.
      Citations: 19     Fields:    Translation:AnimalsCells
    155. Liou GI, Geng L, al-Ubaidi MR, Matragoon S, Hanten G, Baehr W, Overbeek PA. Tissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding protein. J Biol Chem. 1990 May 25; 265(15):8373-6. PMID: 2160453.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    156. Epstein PN, Overbeek PA, Means AR. Calmodulin-induced early-onset diabetes in transgenic mice. Cell. 1989 Sep 22; 58(6):1067-73. PMID: 2673540.
      Citations: 78     Fields:    Translation:AnimalsCells
    157. Shawlot W, Siciliano MJ, Stallings RL, Overbeek PA. Insertional inactivation of the downless gene in a family of transgenic mice. Mol Biol Med. 1989 Aug; 6(4):299-307. PMID: 2622338.
      Citations: 14     Fields:    Translation:AnimalsCells
    158. Mahon KA, Overbeek PA, Westphal H. Prenatal lethality in a transgenic mouse line is the result of a chromosomal translocation. Proc Natl Acad Sci U S A. 1988 Feb; 85(4):1165-8. PMID: 2829218; PMCID: PMC279727.
      Citations: 14     Fields:    Translation:AnimalsCells
    159. Chepelinsky AB, Khillan JS, Mahon KA, Overbeek PA, Westphal H, Piatigorsky J. Crystallin genes: lens specificity of the murine alpha A-crystallin gene. Environ Health Perspect. 1987 Nov; 75:17-24. PMID: 3691437; PMCID: PMC1474452.
      Citations:    Fields:    Translation:Animals
    160. Mahon KA, Chepelinsky AB, Khillan JS, Overbeek PA, Piatigorsky J, Westphal H. Oncogenesis of the lens in transgenic mice. Science. 1987 Mar 27; 235(4796):1622-8. PMID: 3029873.
      Citations: 58     Fields:    Translation:AnimalsCells
    161. Overbeek PA, Lai SP, Van Quill KR, Westphal H. Tissue-specific expression in transgenic mice of a fused gene containing RSV terminal sequences. Science. 1986 Mar 28; 231(4745):1574-7. PMID: 3006249.
      Citations: 47     Fields:    Translation:AnimalsCells
    162. Khillan JS, Schmidt A, Overbeek PA, de Crombrugghe B, Westphal H. Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice. Proc Natl Acad Sci U S A. 1986 Feb; 83(3):725-9. PMID: 3456166; PMCID: PMC322937.
      Citations: 22     Fields:    Translation:AnimalsCells
    163. Overbeek PA, Chepelinsky AB, Khillan JS, Piatigorsky J, Westphal H. Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice. Proc Natl Acad Sci U S A. 1985 Dec; 82(23):7815-9. PMID: 3865198; PMCID: PMC390860.
      Citations: 70     Fields:    Translation:AnimalsCells
    164. Khillan JS, Overbeek PA, Westphal H. Drosophila P element integration in the mouse. Dev Biol. 1985 May; 109(1):247-50. PMID: 3921415.
      Citations: 8     Fields:    Translation:Animals
    165. Westphal H, Overbeek PA, Khillan JS, Chepelinsky AB, Schmidt A, Mahon KA, Bernstein KE, Piatigorsky J, de Crombrugghe B. Promoter sequences of murine alpha A crystallin, murine alpha 2(I) collagen or of avian sarcoma virus genes linked to the bacterial chloramphenicol acetyl transferase gene direct tissue-specific patterns of chloramphenicol acetyl transferase expression in transgenic mice. Cold Spring Harb Symp Quant Biol. 1985; 50:411-6. PMID: 3006999.
      Citations: 3     Fields:    Translation:AnimalsCells
    166. Overbeek PA, Merlino GT, Peters NK, Cohn VH, Moore GP, Kleinsmith LJ. Characterization of five members of the actin gene family in the sea urchin. Biochim Biophys Acta. 1981 Dec 28; 656(2):195-205. PMID: 6172152.
      Citations: 14     Fields:    Translation:AnimalsCells
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