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ASHOK BALASUBRAMANYAM

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


    Collapse Research 
    Collapse research activities and funding
    U54DK118638     (BALASUBRAMANYAM, ASHOK ;KRISCHER, JEFFREY P)Sep 10, 2018 - May 31, 2024
    NIH
    Center for Identification and Study of Individuals with Atypical Diabetes Mellitus (U54)
    Role: Principal Investigator
    R01DK104832     (BALASUBRAMANYAM, ASHOK)Sep 16, 2015 - Aug 31, 2021
    NIH
    Role of Islet Injury and Autoimmunity in T2D Beta Cell Dysfunction
    Role: Principal Investigator
    R01DK101411     (JAHOOR, FAROOK)Sep 11, 2014 - Jun 30, 2021
    NIH
    Arginine and Nitric Oxide Synthesis in the Pathogenesis of Ketosis-Prone Diabetes
    Role: Co-Principal Investigator
    R33AI116208     (LEWIS, DOROTHY E.)Sep 1, 2014 - Aug 31, 2019
    NIH
    Adipose Tissue is a significant reservoir for HIV
    Role: Co-Principal Investigator
    R21AI116208     (LEWIS, DOROTHY E.)Sep 1, 2014 - Aug 31, 2016
    NIH
    Adipose Tissue is a significant reservoir for HIV
    Role: Co-Principal Investigator
    R01DK081553     (BALASUBRAMANYAM, ASHOK)May 15, 2009 - Mar 31, 2015
    NIH
    Viral mechanisms of adipocyte dysfuntion: Role of Vpr.
    Role: Principal Investigator
    R21DK082827     (BALASUBRAMANYAM, ASHOK)Apr 10, 2009 - Mar 31, 2012
    NIH
    Pathogenesis of Ketosis Prone Diabetes
    Role: Principal Investigator
    R01HL073696     (BALASUBRAMANYAM, ASHOK)Sep 1, 2003 - Jul 31, 2010
    NIH
    Diet/Exercise, Niacin, Fenofibrate for HIV Lipodystrophy
    Role: Principal Investigator
    R01DK059537     (BALASUBRAMANYAM, ASHOK)Aug 1, 2001 - Jun 30, 2005
    NIH
    MOLECULAR BASIS OF HIV LIPODYSTROPHY: ROLE OF VPR
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Utzschneider KM, Younes N, Butera NM, Balasubramanyam A, Bergenstal RM, Barzilay J, DeSouza C, DeFronzo RA, Elasy T, Krakoff J, Kahn SE, Rasouli N, Valencia WM, Sivitz WI, GRADE Research Group . Impact of Insulin Sensitivity and ?-Cell Function Over Time on Glycemic Outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE): Differential Treatment Effects of Dual Therapy. Diabetes Care. 2024 Apr 01; 47(4):571-579. PMID: 38190619; PMCID: PMC10973903.
      Citations:    Fields:    Translation:Humans
    2. Cherrington AL, Bebu I, Krause-Steinrauf H, Hoogendoorn CJ, Crespo-Ramos G, Presley C, Naik AD, Balasubramanyam A, Gramzinski MR, Killean T, Arends VL, Gonzalez JS, GRADE Research Group , Naik AD, Balasubramanyam A. Does Emotional Distress Predict Worse Glycemic Control Over Time? Results From the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care. 2024 Apr 01; 47(4):620-628. PMID: 38252848; PMCID: PMC10973910.
      Citations: 1     Fields:    Translation:Humans
    3. Ramirez Bustamante CE, Agarwal N, Cox AR, Hartig SM, Lake JE, Balasubramanyam A, Ramirez Bustamante CE, Agarwal N, Cox AR, Hartig SM, Lake JE, Balasubramanyam A. Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV. Endocr Rev. 2024 Mar 04; 45(2):190-209. PMID: 37556371; PMCID: PMC10911955.
      Citations:    Fields:    Translation:Humans
    4. Bancks MP, Pilla SJ, Balasubramanyam A, Yeh HC, Johnson KC, Rigdon J, Wagenknecht LE, Espeland MA, Bancks MP, Pilla SJ, Balasubramanyam A, Yeh HC, Johnson KC, Rigdon J, Wagenknecht LE, Espeland MA. Association of Lifestyle Intervention With Risk for Cardiovascular Events Differs by Level of Glycated Hemoglobin. J Clin Endocrinol Metab. 2024 Feb 20; 109(3):e1012-e1019. PMID: 37978826; PMCID: PMC10876384.
      Citations: 1     Fields:    Translation:Humans
    5. Stone SI, Balasubramanyam A, Posey JE. Atypical Diabetes: What Have We Learned and What Does the Future Hold? Diabetes Care. 2024 Feb 08. PMID: 38329838.
      Citations:    Fields:    
    6. Smith EEA, Nachimuthu N, Flynn J, Balasubramanyam A, Negrete JA, Trautner BW, Al Mohajer M. Assessing clinicians' and trainees' knowledge and practice of the IDSA guidelines for asymptomatic bacteriuria in older adults. Infect Control Hosp Epidemiol. 2024 Jan 22; 1-3. PMID: 38251669.
      Citations:    Fields:    
    7. Hampe CS, Shojaie A, Brooks-Worrell B, Dibay S, Utzschneider K, Kahn SE, Larkin ME, Johnson ML, Younes N, Rasouli N, Desouza C, Cohen RM, Park JY, Florez HJ, Valencia WM, Stempel R, Palmer JP, Balasubramanyam A. GAD65Abs Are Not Associated With Beta-Cell Dysfunction in Patients With T2D in the GRADE Study. J Endocr Soc. 2024 Jan 16; 8(3):bvad179. PMID: 38333889; PMCID: PMC10853002.
      Citations: 1     
    8. Erlandson KM, Mohaweche R, Morrow M, Mawhinney S, Khuu V, Boyd M, Balasubramanyam A, Melanson EL, Lake JE. Energy balance and body composition after switch between integrase strand transfer inhibitors and doravirine among people with HIV. J Antimicrob Chemother. 2024 Jan 03; 79(1):179-185. PMID: 38000089; PMCID: PMC10761240.
      Citations:    Fields:    Translation:Humans
    9. Rodriguez BC, Astudillo M, Tosur M, Rafaey A, McKay S, Bacha F, Balasubramanyam A, Redondo MJ. Characteristics of Type 2 Diabetes in Female and Male Youth. Clin Diabetes. 2023; 41(2):239-243. PMID: 37092145; PMCID: PMC10115763.
      Citations:    
    10. Osafehinti D, Mulukutla SN, Hampe CS, Gaba R, Ram N, Balasubramanyam A, Weedon MN, Oram RA. Type 1 Diabetes Genetic Risk Score Differentiates Subgroups of Ketosis-Prone Diabetes. Diabetes Care. 2023 10 01; 46(10):1778-1782. PMID: 37506364; PMCID: PMC10516251.
      Citations:    Fields:    Translation:HumansCells
    11. Tosur M, Hsu JW, Deen S, Huang X, Guffey D, Uysal S, Astudillo M, Redondo MJ, Jahoor F, Balasubramanyam A. Plasma amino acid signatures define types of pediatric diabetes. Clin Nutr ESPEN. 2023 10; 57:21-28. PMID: 37739658; PMCID: PMC10518839.
      Citations:    Fields:    Translation:HumansAnimals
    12. Yang D, Patel S, Szlachcic WJ, Chmielowiec J, Scaduto D, Putluri N, Sreekumar A, Suliburk J, Metzker M, Balasubramanyam A, Borowiak M. Erratum. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes 2021;70:2419-2429. Diabetes. 2023 Jun 01; 72(6):821. PMID: 37067510; PMCID: PMC10202761.
      Citations:    Fields:    
    13. Bancks MP, Lovato J, Balasubramanyam A, Coday M, Johnson KC, Munshi M, Rebello C, Wagenknecht LE, Espeland MA. Association of Type 2 Diabetes Subgroups With Cognitive Status Without Modification From Lifestyle Intervention. J Clin Endocrinol Metab. 2023 05 17; 108(6):e334-e342. PMID: 36472933; PMCID: PMC10413427.
      Citations:    Fields:    Translation:Humans
    14. Parikh HM, Remedios CL, Hampe CS, Balasubramanyam A, Fisher-Hoch SP, Choi YJ, Patel S, McCormick JB, Redondo MJ, Krischer JP. Data Mining Framework for Discovering and Clustering Phenotypes of Atypical Diabetes. J Clin Endocrinol Metab. 2023 03 10; 108(4):834-846. PMID: 36314086; PMCID: PMC10211492.
      Citations: 2     Fields:    Translation:Humans
    15. Faruqi J, Balasubramanyam A. COVID-19 and diabetes mellitus: a review of the incidence, pathophysiology and management of diabetes during the pandemic. Expert Rev Endocrinol Metab. 2023 03; 18(2):167-179. PMID: 36797835.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    16. Tosur M, Gandolfo L, Balasubramanyam A, Naylor RN, Pollin TI, Rasouli N, Cromer SJ, Buse JB, Redondo MJ, RADIANT Study Group. Enrollment of underrepresented racial and ethnic groups in the Rare and Atypical Diabetes Network (RADIANT). J Clin Transl Sci. 2023; 7(1):e47. PMID: 36845305; PMCID: PMC9947614.
      Citations: 1     
    17. Kikani N, Balasubramanyam A. Remission in Ketosis-Prone Diabetes. Endocrinol Metab Clin North Am. 2023 03; 52(1):165-174. PMID: 36754492.
      Citations:    Fields:    Translation:Humans
    18. Patel KV, Khan MS, Bahnson JL, Garcia KR, Balasubramanyam A, Verma S, Espeland M, Pandey A, Segar MW, Clark JM, Bertoni AG, Vaduganathan M, Farkouh ME, Januzzi JL. Optimal Cardiometabolic Health and Risk of Heart Failure in Type 2 Diabetes: An Analysis from the Look AHEAD Trial. Eur J Heart Fail. 2022 Oct 24. PMID: 36280384.
      Citations:    Fields:    
    19. GRADE Study Research Group, Nathan DM, Lachin JM, Balasubramanyam A, Burch HB, Buse JB, Butera NM, Cohen RM, Crandall JP, Kahn SE, Krause-Steinrauf H, Larkin ME, Rasouli N, Tiktin M, Wexler DJ, Younes N. Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes. N Engl J Med. 2022 09 22; 387(12):1063-1074. PMID: 36129996; PMCID: PMC9829320.
      Citations:    
    20. Zimolzak AJ, Davila JA, Punugoti V, Balasubramanyam A, Klotman PE, Petersen LA, Rochat RH, Liao G, Laubscher RR, Leiber L, Amos CI. Lessons learned from an enterprise-wide clinical datathon. J Clin Transl Sci. 2022; 6(1):e125. PMID: 36590351; PMCID: PMC9794964.
      Citations:    
    21. Agarwal N, Ramirez Bustamante CE, Wu H, Armamento-Villareal R, Lake JE, Balasubramanyam A, Hartig SM. Heightened levels of plasma growth differentiation factor 15 in men living with HIV. Physiol Rep. 2022 05; 10(9):e15293. PMID: 35510313; PMCID: PMC9069165.
      Citations: 1     Fields:    Translation:Humans
    22. Wing RR, Neiberg RH, Bahnson JL, Clark JM, Espeland MA, Hill JO, Johnson KC, Knowler WC, Olson K, Steinburg H, Pi-Sunyer X, Wadden TA, Wyatt H, on behalf on the Look AHEAD Research Group. Weight Change During the Postintervention Follow-up of Look AHEAD. Diabetes Care. 2022 04 14. PMID: 35421225; PMCID: PMC9277114.
      Citations:    Fields:    
    23. Menon S, Refaey A, Guffey D, Balasubramanyam A, Redondo MJ, Tosur M. Optimizing maturity-onset diabetes of the young detection in a pediatric diabetes population. Pediatr Diabetes. 2022 06; 23(4):447-456. PMID: 35218126.
      Citations:    Fields:    Translation:Humans
    24. Pradhan G, Lee JH, Wu CS, Wang H, Lin L, Donti T, Graham BH, Rajan AS, Balasubramanyam A, Samson SL, Guo S, Sun Y. Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets. Biomolecules. 2022 03 06; 12(3). PMID: 35327599; PMCID: PMC8945998.
      Citations:    Fields:    Translation:Animals
    25. Vaughan EM, Johnson E, Naik AD, Amspoker AB, Balasubramanyam A, Virani SS, Ballantyne CM, Johnston CA, Foreyt JP. Long-Term Effectiveness of the TIME Intervention to Improve Diabetes Outcomes in Low-Income Settings: a 2-Year Follow-Up. J Gen Intern Med. 2022 09; 37(12):3062-3069. PMID: 35132555; PMCID: PMC8821843.
      Citations:    Fields:    
    26. Gaba R, Balasubramanyam A. Covid-19: A new cause of "provoked" A-?+ Ketosis-Prone Diabetes. J Diabetes Complications. 2022 04; 36(4):108147. PMID: 35153127; PMCID: PMC8820105.
      Citations:    Fields:    Translation:Humans
    27. Brooks-Worrell B, Hampe CS, Hattery EG, Palomino B, Zangeneh SZ, Utzschneider K, Kahn SE, Larkin ME, Johnson ML, Mather KJ, Younes N, Rasouli N, Desouza C, Cohen RM, Park JY, Florez HJ, Valencia WM, GRADE Beta-cell Ancillary Study Network, Shojaie A, Palmer JP, Balasubramanyam A. Islet Autoimmunity is Highly Prevalent and Associated With Diminished ?-Cell Function in Patients With Type 2 Diabetes in the Grade Study. Diabetes. 2022 Jan 21. PMID: 35061024; PMCID: PMC9375448.
      Citations:    Fields:    
    28. Redondo MJ, Balasubramanyam A. Toward an Improved Classification of Type 2 Diabetes: Lessons From Research into the Heterogeneity of a Complex Disease. J Clin Endocrinol Metab. 2021 11 19; 106(12):e4822-e4833. PMID: 34291809; PMCID: PMC8787852.
      Citations: 2     Fields:    Translation:Humans
    29. Barzilay JI, Ghosh A, Busui RP, Ahmann A, Balasubramanyam A, Banerji MA, Cohen RM, Green J, Ismail-Beigi F, Martin CL, Seaquist E, GRADE Research Group, Luchsinger JA. The cross-sectional association of cognition with diabetic peripheral and autonomic neuropathy-The GRADE study. J Diabetes Complications. 2021 12; 35(12):108047. PMID: 34556408; PMCID: PMC8608739.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    30. Astudillo M, Tosur M, Castillo B, Rafaey A, Siller AF, Nieto J, Sisley S, McKay S, Nella AA, Balasubramanyam A, Bacha F, Redondo MJ. Type 2 diabetes in prepubertal children. Pediatr Diabetes. 2021 11; 22(7):946-950. PMID: 34363430.
      Citations: 5     Fields:    Translation:Humans
    31. Tosur M, Soler-Alfonso C, Chan KM, Khayat MM, Jhangiani SN, Meng Q, Refaey A, Muzny D, Gibbs RA, Murdock DR, Posey JE, Balasubramanyam A, Redondo MJ, Sabo A. Exome sequencing in children with clinically suspected maturity-onset diabetes of the young. Pediatr Diabetes. 2021 11; 22(7):960-968. PMID: 34387403; PMCID: PMC8530905.
      Citations:    Fields:    Translation:Humans
    32. Murdock DR, Venner E, Muzny DM, Metcalf GA, Murugan M, Hadley TD, Chander V, de Vries PS, Jia X, Hussain A, Agha AM, Sabo A, Li S, Meng Q, Hu J, Tian X, Cohen M, Yi V, Kovar CL, Gingras MC, Korchina V, Howard C, Riconda DL, Pereira S, Smith HS, Huda ZA, Buentello A, Marino PR, Leiber L, Balasubramanyam A, Amos CI, Civitello AB, Chelu MG, Maag R, McGuire AL, Boerwinkle E, Wehrens XHT, Ballantyne CM, Gibbs RA. Genetic testing in ambulatory cardiology clinics reveals high rate of findings with clinical management implications. Genet Med. 2021 12; 23(12):2404-2414. PMID: 34363016; PMCID: PMC8931845.
      Citations: 3     Fields:    Translation:Humans
    33. Yang D, Patel S, Szlachcic WJ, Chmielowiec J, Scaduto D, Putluri N, Sreekumar A, Suliburk J, Metzker M, Balasubramanyam A, Borowiak M. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes. 2021 10; 70(10):2419-2429. PMID: 34344789; PMCID: PMC8576504.
      Citations:    Fields:    Translation:HumansCells
    34. Vaughan EM, Naik AD, Amspoker AB, Johnston CA, Landrum JD, Balasubramanyam A, Virani SS, Ballantyne CM, Foreyt JP. Mentored implementation to initiate a diabetes program in an underserved community: a pilot study. BMJ Open Diabetes Res Care. 2021 08; 9(1). PMID: 34385148; PMCID: PMC8362735.
      Citations: 1     Translation:Humans
    35. Agarwal N, Iyer D, Saha P, Cox AR, Xia Y, Utay NS, Somasundaram A, Schubert U, Lake JE, Hartig SM, Balasubramanyam A. HIV-1 Viral Protein R Couples Metabolic Inflexibility With White Adipose Tissue Thermogenesis. Diabetes. 2021 09; 70(9):2014-2025. PMID: 34233931; PMCID: PMC8576429.
      Citations: 1     Fields:    Translation:Humans
    36. Lee HH, McGeary JE, Dunsiger S, Baker L, Balasubramanyam A, Knowler WC, Williams DM. The Moderating Effects of Genetic Variations on Changes in Physical Activity Level and Cardiorespiratory Fitness in Response to a Life-Style Intervention: A Randomized Controlled Trial. Psychosom Med. 2021 06 01; 83(5):440-448. PMID: 34080585; PMCID: PMC9922170.
      Citations: 1     Fields:    Translation:Humans
    37. Nieto J, Castillo B, Astudillo M, Tosur M, Balasubramanyam A, Pietropaolo M, Redondo MJ. Islet autoantibody types mark differential clinical characteristics at diagnosis of pediatric type 1 diabetes. Pediatr Diabetes. 2021 09; 22(6):882-888. PMID: 34018301.
      Citations:    Fields:    Translation:Humans
    38. Jahoor F, Hsu JW, Mehta PB, Keene KR, Gaba R, Mulukutla SN, Caducoy E, Peacock WF, Patel SG, Bennet R, Lernmark A, Balasubramanyam A. Metabolomics Profiling of Patients With A-?+ Ketosis-Prone Diabetes During Diabetic Ketoacidosis. Diabetes. 2021 08; 70(8):1898-1909. PMID: 34021044; PMCID: PMC8385613.
      Citations: 2     Fields:    Translation:Humans
    39. Bancks MP, Chen H, Balasubramanyam A, Bertoni AG, Espeland MA, Kahn SE, Pilla S, Vaughan E, Wagenknecht LE, Look AHEAD Research Group. Type 2 Diabetes Subgroups, Risk for Complications, and Differential Effects Due to an Intensive Lifestyle Intervention. Diabetes Care. 2021 05; 44(5):1203-1210. PMID: 33707304; PMCID: PMC8132317.
      Citations: 4     Fields:    Translation:Humans
    40. Rasouli N, Younes N, Utzschneider KM, Inzucchi SE, Balasubramanyam A, Cherrington AL, Ismail-Beigi F, Cohen RM, Olson DE, DeFronzo RA, Herman WH, Lachin JM, Kahn SE, GRADE Research Group. Association of Baseline Characteristics With Insulin Sensitivity and ?-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort. Diabetes Care. 2021 02; 44(2):340-349. PMID: 33334808; PMCID: PMC7818323.
      Citations: 3     Fields:    Translation:Humans
    41. Tosur M, Cleves MA, Sosenko JM, Libman I, Baidal DA, Balasubramanyam A, Redondo MJ, Type 1 Diabetes TrialNet Study Group. The Effect of Ethnicity in the Rate of Beta-Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. J Clin Endocrinol Metab. 2020 12 01; 105(12). PMID: 32502242; PMCID: PMC7531906.
      Citations: 1     Fields:    Translation:HumansCells
    42. Balasubramanyam A. Defining and Classifying New Subgroups of Diabetes. Annu Rev Med. 2021 01 27; 72:63-74. PMID: 33064971.
      Citations: 3     Fields:    Translation:Humans
    43. Redondo MJ, Hagopian WA, Oram R, Steck AK, Vehik K, Weedon M, Balasubramanyam A, Dabelea D. The clinical consequences of heterogeneity within and between different diabetes types. Diabetologia. 2020 10; 63(10):2040-2048. PMID: 32894314; PMCID: PMC8498993.
      Citations: 18     Fields:    Translation:Humans
    44. Pandey A, Patel KV, Bahnson JL, Gaussoin SA, Martin CK, Balasubramanyam A, Johnson KC, McGuire DK, Bertoni AG, Kitzman D, Berry JD, Look AHEAD Research Group. Association of Intensive Lifestyle Intervention, Fitness, and Body Mass Index With Risk of Heart Failure in Overweight or Obese Adults With Type 2 Diabetes Mellitus: An Analysis From the Look AHEAD Trial. Circulation. 2020 04 21; 141(16):1295-1306. PMID: 32134326; PMCID: PMC9976290.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    45. Couturier J, Nuotio-Antar AM, Agarwal N, Wilkerson GK, Saha P, Kulkarni V, Lakhashe SK, Esquivel J, Nehete PN, Ruprecht RM, Sastry KJ, Meyer JM, Hill LR, Lake JE, Balasubramanyam A, Lewis DE. Lymphocytes upregulate CD36 in adipose tissue and liver. Adipocyte. 2019 12; 8(1):154-163. PMID: 31035848; PMCID: PMC6768236.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    46. Mulukutla SN, Acevedo-Calado M, Hampe CS, Pietropaolo M, Balasubramanyam A. Response to Comment on Mulukutla et al. Autoantibodies to the IA-2 Extracellular Domain Refine the Definition of "A+" Subtypes of Ketosis-Prone Diabetes. Diabetes Care 2018;41:2637-2640. Diabetes Care. 2019 05; 42(5):e82-e83. PMID: 31010950; PMCID: PMC6489110.
      Citations:    Fields:    Translation:Humans
    47. Gaba R, Mehta P, Balasubramanyam A. Evaluation and management of ketosis-prone diabetes. Expert Rev Endocrinol Metab. 2019 01; 14(1):43-48. PMID: 30612498.
      Citations: 1     Fields:    Translation:HumansCells
    48. Pilla SJ, Balasubramanyam A, Knowler WC, Lazo M, Nathan DM, Pi-Sunyer X, Clark JM, Maruthur NM, Look AHEAD Research Group. Islet autoantibody positivity in overweight and obese adults with type 2 diabetes. Autoimmunity. 2018 12; 51(8):408-416. PMID: 30661481; PMCID: PMC6362362.
      Citations: 7     Fields:    Translation:Humans
    49. Balasubramanyam A. SYNDROMES OF KETOSIS-PRONE DIABETES. Trans Am Clin Climatol Assoc. 2019; 130:145-155. PMID: 31516178; PMCID: PMC6736014.
      Citations: 1     Fields:    Translation:HumansCells
    50. Mulukutla SN, Acevedo-Calado M, Hampe CS, Pietropaolo M, Balasubramanyam A. Autoantibodies to the IA-2 Extracellular Domain Refine the Definition of "A+" Subtypes of Ketosis-Prone Diabetes. Diabetes Care. 2018 12; 41(12):2637-2640. PMID: 30327357; PMCID: PMC6245211.
      Citations: 2     Fields:    Translation:HumansCells
    51. Hendrie HC, Zheng M, Lane KA, Ambuehl R, Purnell C, Li S, Unverzagt FW, Murray MD, Balasubramanyam A, Callahan CM, Gao S. Changes of glucose levels precede dementia in African-Americans with diabetes but not in Caucasians. Alzheimers Dement. 2018 12; 14(12):1572-1579. PMID: 29678640; PMCID: PMC6192866.
      Citations: 2     Fields:    Translation:Humans
    52. Couturier J, Winchester LC, Suliburk JW, Wilkerson GK, Podany AT, Agarwal N, Xuan Chua CY, Nehete PN, Nehete BP, Grattoni A, Sastry KJ, Fletcher CV, Lake JE, Balasubramanyam A, Lewis DE. Adipocytes impair efficacy of antiretroviral therapy. Antiviral Res. 2018 06; 154:140-148. PMID: 29630975; PMCID: PMC5955795.
      Citations: 17     Fields:    Translation:HumansCells
    53. Mulukutla SN, Hsu JW, Gaba R, Bohren KM, Guthikonda A, Iyer D, Ajami NJ, Petrosino JF, Hampe CS, Ram N, Jahoor F, Balasubramanyam A. Arginine Metabolism Is Altered in Adults with A-?+?Ketosis-Prone Diabetes. J Nutr. 2018 02 01; 148(2):185-193. PMID: 29490093; PMCID: PMC6251649.
      Citations: 5     Fields:    Translation:HumansCells
    54. Mulukutla SN, Tersey SA, Hampe CS, Mirmira RG, Balasubramanyam A. Elevated unmethylated and methylated insulin DNA are unique markers of A+?+ ketosis prone diabetes. J Diabetes Complications. 2018 02; 32(2):193-195. PMID: 29175121; PMCID: PMC6170161.
      Citations: 4     Fields:    Translation:HumansCells
    55. Agarwal N, Iyer D, Gabbi C, Saha P, Patel SG, Mo Q, Chang B, Goswami B, Kopp JB, Lewis DE, Balasubramanyam A, Schubert U. HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRa and PPARa dysregulation: implications for HIV-specific pathogenesis of NAFLD. Sci Rep. 2017 10 17; 7(1):13362. PMID: 29042644; PMCID: PMC5645472.
      Citations: 14     Fields:    Translation:AnimalsCells
    56. Balasubramanyam A, Fossen T, Hahn F, Schmalen A, Setz C, Friedrich M, Schl??er S, K?lle J, Spranger R, Rauch P, Fraedrich K, Reif T, Karius-Fischer J, Henklein P, Schubert U. Proteolysis of mature HIV-1 p6 Gag protein by the insulin-degrading enzyme (IDE) regulates virus replication in an Env-dependent manner. PLoS One. 2017; 12(4):e0174254. PMID: 28388673; PMCID: PMC5384750.
      Citations: 7     Fields:    Translation:HumansCells
    57. Bruera S, Kalakota NR, Balasubramanyam A. The Malnourished Heart: An Unusual Case of Heart Failure. Am J Med. 2017 Jul; 130(7):e297-e298. PMID: 28219636.
      Citations: 2     Fields:    Translation:Humans
    58. Patel RM, Misra R, Raj S, Balasubramanyam A. Effectiveness of a Group-Based Culturally Tailored Lifestyle Intervention Program on Changes in Risk Factors for Type 2 Diabetes among Asian Indians in the United States. J Diabetes Res. 2017; 2017:2751980. PMID: 28168201; PMCID: PMC5266805.
      Citations: 11     Fields:    Translation:Humans
    59. Bashamboo A, Donohoue PA, Vilain E, Rojo S, Calvel P, Seneviratne SN, Buonocore F, Barseghyan H, Bingham N, Rosenfeld JA, Mulukutla SN, Jain M, Burrage L, Dhar S, Balasubramanyam A, Lee B, Members of UDN, Dumargne MC, Eozenou C, Suntharalingham JP, de Silva K, Lin L, Bignon-Topalovic J, Poulat F, McElreavey K, Achermann JC, Lagos CF. A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development. Hum Mol Genet. 2016 12 01; 25(23):5286. PMID: 28031288; PMCID: PMC5886042.
      Citations: 8     Fields:    
    60. Hendrie HC, Zheng M, Li W, Lane K, Ambuehl R, Purnell C, Unverzagt FW, Torke A, Balasubramanyam A, Callahan CM, Gao S. Glucose level decline precedes dementia in elderly African Americans with diabetes. Alzheimers Dement. 2017 02; 13(2):111-118. PMID: 27793691; PMCID: PMC5318260.
      Citations: 4     Fields:    Translation:Humans
    61. Bashamboo A, Donohoue PA, Vilain E, Rojo S, Calvel P, Seneviratne SN, Buonocore F, Barseghyan H, Bingham N, Rosenfeld JA, Mulukutla SN, Jain M, Burrage L, Dhar S, Balasubramanyam A, Lee B, Members of UDN, Dumargne MC, Eozenou C, Suntharalingham JP, de Silva K, Lin L, Bignon-Topalovic J, Poulat F, McElreavey K, Achermann JC, Lagos CF. A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development. Hum Mol Genet. 2016 08 15; 25(16):3446-3453. PMID: 27378692; PMCID: PMC5179941.
      Citations: 28     Fields:    Translation:Humans
    62. Sanguankeo A, Lazo M, Upala S, Brancati FL, Bonekamp S, Pownall HJ, Balasubramanyam A, Clark JM, Fatty Liver Subgroup of the Look AHEAD Research Group. Effects of visceral adipose tissue reduction on CVD risk factors independent of weight loss: The Look AHEAD study. Endocr Res. 2017 May; 42(2):86-95. PMID: 27351077; PMCID: PMC5573136.
      Citations: 1     Fields:    Translation:Humans
    63. Couturier J, Agarwal N, Nehete PN, Baze WB, Barry MA, Jagannadha Sastry K, Balasubramanyam A, Lewis DE. Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques. Retrovirology. 2016 Apr 27; 13:30. PMID: 27117277; PMCID: PMC4847269.
      Citations: 19     Fields:    Translation:AnimalsCells
    64. Andersen LW, Berg KM, Montissol S, Sulmonte C, Balkema J, Cocchi MN, Wolfe RE, Balasubramanyam A, Liu X, Donnino MW. Pyruvate Dehydrogenase Activity Is Decreased in Emergency Department Patients With Diabetic Ketoacidosis. Acad Emerg Med. 2016 06; 23(6):685-9. PMID: 26733088.
      Citations: 1     Fields:    Translation:HumansCells
    65. Belalcazar LM, Papandonatos GD, Erar B, Peter I, Alkofide H, Balasubramanyam A, Brautbar A, Kahn SE, Knowler WC, Ballantyne CM, McCaffery JM, Huggins GS, Genetics Subgroup of the Look AHEAD Study*. Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD. Circ Cardiovasc Genet. 2016 Feb; 9(1):71-8. PMID: 26578543; PMCID: PMC4758870.
      Citations: 1     Fields:    Translation:Humans
    66. Belalcazar LM, Lang W, Haffner SM, Schwenke DC, Kriska A, Balasubramanyam A, Hoogeveen RC, Pi-Sunyer FX, Tracy RP, Ballantyne CM, Look AHEAD (Action for Health in Diabetes) Research Group. Improving Adiponectin Levels in Individuals With Diabetes and Obesity: Insights From Look AHEAD. Diabetes Care. 2015 Aug; 38(8):1544-50. PMID: 25972574; PMCID: PMC4512135.
      Citations: 11     Fields:    Translation:Humans
    67. Gaba R, Gambhire D, Uy N, Gonzalez EV, Iyer D, Hampe CS, Ram N, Balasubramanyam A. Factors associated with early relapse to insulin dependence in unprovoked A-?+ ketosis-prone diabetes. J Diabetes Complications. 2015 Sep-Oct; 29(7):918-22. PMID: 26071380; PMCID: PMC4540630.
      Citations: 8     Fields:    Translation:HumansCells
    68. Couturier J, Suliburk JW, Brown JM, Luke DJ, Agarwal N, Yu X, Nguyen C, Iyer D, Kozinetz CA, Overbeek PA, Metzker ML, Balasubramanyam A, Lewis DE. Human adipose tissue as a reservoir for memory CD4+ T cells and HIV. AIDS. 2015 Mar 27; 29(6):667-74. PMID: 25849830; PMCID: PMC4389783.
      Citations: 63     Fields:    Translation:HumansCells
    69. Belalcazar LM, Papandonatos GD, McCaffery JM, Peter I, Pajewski NM, Erar B, Allred ND, Balasubramanyam A, Bowden DW, Brautbar A, Pi-Sunyer FX, Ballantyne CM, Huggins GS, Look AHEAD Research Group. A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. Physiol Genomics. 2015 Jun; 47(6):215-24. PMID: 25759378; PMCID: PMC4451387.
      Citations: 4     Fields:    Translation:Humans
    70. Davidson LE, Kelley DE, Heshka S, Thornton J, Pi-Sunyer FX, Boxt L, Balasubramanyam A, Gallagher D, MRI Ancillary Study Subgroup of the Look AHEAD Research Group. Skeletal muscle and organ masses differ in overweight adults with type 2 diabetes. J Appl Physiol (1985). 2014 Aug 15; 117(4):377-82. PMID: 24947030; PMCID: PMC4137236.
      Citations: 8     Fields:    Translation:Humans
    71. Ladenson PW, Balasubramanyam A, Danoff A, Bhasin S. Defining, assessing, and certifying procedural competency in endocrinology, diabetes, and metabolism. J Clin Endocrinol Metab. 2014 Aug; 99(8):2651-3. PMID: 24823467.
      Citations:    Fields:    Translation:Humans
    72. Redondo MJ, Muniz J, Rodriguez LM, Iyer D, Haymond MW, Hampe CS, Metzker ML, Grant SF, Balasubramanyam A, Vaziri-Sani F. Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes. BMJ Open Diabetes Res Care. 2014; 2(1):e000008. PMID: 25452857; PMCID: PMC4212574.
      Citations: 16     
    73. Oak S, Gaur LK, Radtke J, Patel R, Iyer D, Ram N, Gaba R, Balasubramanyam A, Hampe CS. Masked and overt autoantibodies specific to the DPD epitope of 65-kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved ?-cell functional reserve in ketosis-prone diabetes. J Clin Endocrinol Metab. 2014 Jun; 99(6):E1040-4. PMID: 24601691; PMCID: PMC4037721.
      Citations: 4     Fields:    Translation:HumansCells
    74. Balasubramanyam A. The villain with a thousand faces. J Diabetes Complications. 2014 Jul-Aug; 28(4):434-5. PMID: 24768207; PMCID: PMC4407363.
      Citations:    Fields:    Translation:HumansAnimals
    75. Peter I, Papandonatos GD, Belalcazar LM, Yang Y, Erar B, Jakicic JM, Unick JL, Balasubramanyam A, Lipkin EW, Delahanty LM, Wagenknecht LE, Wing RR, McCaffery JM, Huggins GS, Look AHEAD Research Group. Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention. Med Sci Sports Exerc. 2014 Feb; 46(2):302-11. PMID: 23899896; PMCID: PMC4055466.
      Citations: 15     Fields:    Translation:Humans
    76. Agarwal N, Iyer D, Patel SG, Sekhar RV, Phillips TM, Schubert U, Oplt T, Buras ED, Samson SL, Couturier J, Lewis DE, Rodriguez-Barradas MC, Jahoor F, Kino T, Kopp JB, Balasubramanyam A. HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation. Sci Transl Med. 2013 Nov 27; 5(213):213ra164. PMID: 24285483; PMCID: PMC4009012.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    77. Brooks-Worrell BM, Iyer D, Coraza I, Hampe CS, Nalini R, Ozer K, Narla R, Palmer JP, Balasubramanyam A. Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes. Diabetes Care. 2013 Dec; 36(12):4098-103. PMID: 24130366; PMCID: PMC3836121.
      Citations: 15     Fields:    Translation:HumansCells
    78. Shrivastav S, Zhang L, Okamoto K, Lee H, Lagranha C, Abe Y, Balasubramanyam A, Lopaschuk GD, Kino T, Kopp JB. HIV-1 Vpr enhances PPAR?/d-mediated transcription, increases PDK4 expression, and reduces PDC activity. Mol Endocrinol. 2013 Sep; 27(9):1564-76. PMID: 23842279; PMCID: PMC3753422.
      Citations: 5     Fields:    Translation:HumansCells
    79. Wooten JS, Nambi P, Gillard BK, Pownall HJ, Coraza I, Scott LW, Nambi V, Ballantyne CM, Balasubramanyam A. Intensive lifestyle modification reduces Lp-PLA2 in dyslipidemic HIV/HAART patients. Med Sci Sports Exerc. 2013 Jun; 45(6):1043-50. PMID: 23299761; PMCID: PMC3655089.
      Citations: 8     Fields:    Translation:HumansCells
    80. Gillard BK, Raya JL, Ruiz-Esponda R, Iyer D, Coraza I, Balasubramanyam A, Pownall HJ. Impaired lipoprotein processing in HIV patients on antiretroviral therapy: aberrant high-density lipoprotein lipids, stability, and function. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1714-21. PMID: 23640486; PMCID: PMC4232239.
      Citations: 13     Fields:    Translation:HumansCells
    81. Misra R, Chandra P, Riechman SE, Long DM, Shinde S, Pownall HJ, Coraza I, Lewis DE, Sekhar RV, Balasubramanyam A. Relationship of ethnicity and CD4 Count with glucose metabolism among HIV patients on Highly-Active Antiretroviral Therapy (HAART). BMC Endocr Disord. 2013 Apr 22; 13:13. PMID: 23607267; PMCID: PMC3751670.
      Citations: 5     Fields:    
    82. Patel PS, Buras ED, Balasubramanyam A. The role of the immune system in obesity and insulin resistance. J Obes. 2013; 2013:616193. PMID: 23577240; PMCID: PMC3618935.
      Citations: 59     Fields:    Translation:HumansCells
    83. Vu CN, Ruiz-Esponda R, Yang E, Chang E, Gillard B, Pownall HJ, Hoogeveen RC, Coraza I, Balasubramanyam A. Altered relationship of plasma triglycerides to HDL cholesterol in patients with HIV/HAART-associated dyslipidemia: further evidence for a unique form of metabolic syndrome in HIV patients. Metabolism. 2013 Jul; 62(7):1014-20. PMID: 23522788; PMCID: PMC3691339.
      Citations: 12     Fields:    Translation:Humans
    84. Redondo MJ, Rodriguez LM, Escalante M, Smith EO, Balasubramanyam A, Haymond MW. Types of pediatric diabetes mellitus defined by anti-islet autoimmunity and random C-peptide at diagnosis. Pediatr Diabetes. 2013 Aug; 14(5):333-40. PMID: 23458188.
      Citations: 13     Fields:    Translation:Humans
    85. Fernandez R, Misra R, Nalini R, Hampe CS, Ozer K, Balasubramanyam A. Characteristics of patients with ketosis-prone diabetes (KPD) presenting with acute pancreatitis: implications for the natural history and etiology of a KPD subgroup. Endocr Pract. 2013 Mar-Apr; 19(2):243-51. PMID: 23529349; PMCID: PMC9595133.
      Citations: 1     Fields:    Translation:HumansCells
    86. Patel SG, Hsu JW, Jahoor F, Coraza I, Bain JR, Stevens RD, Iyer D, Nalini R, Ozer K, Hampe CS, Newgard CB, Balasubramanyam A. Pathogenesis of A??? ketosis-prone diabetes. Diabetes. 2013 Mar; 62(3):912-22. PMID: 23160531; PMCID: PMC3581228.
      Citations: 19     Fields:    Translation:HumansCells
    87. Belalcazar LM, Lang W, Haffner SM, Hoogeveen RC, Pi-Sunyer FX, Schwenke DC, Balasubramanyam A, Tracy RP, Kriska AP, Ballantyne CM, Look AHEAD Research Group. Adiponectin and the mediation of HDL-cholesterol change with improved lifestyle: the Look AHEAD Study. J Lipid Res. 2012 Dec; 53(12):2726-33. PMID: 22956782; PMCID: PMC3494242.
      Citations: 18     Fields:    Translation:Humans
    88. Abdelmalek MF, Lazo M, Horska A, Bonekamp S, Lipkin EW, Balasubramanyam A, Bantle JP, Johnson RJ, Diehl AM, Clark JM, Fatty Liver Subgroup of Look AHEAD Research Group. Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes. Hepatology. 2012 Sep; 56(3):952-60. PMID: 22467259; PMCID: PMC3406258.
      Citations: 79     Fields:    Translation:Humans
    89. Redondo MJ, Rodriguez LM, Escalante M, O'Brian Smith E, Balasubramanyam A, Haymond MW. Beta cell function and BMI in ethnically diverse children with newly diagnosed autoimmune type 1 diabetes. Pediatr Diabetes. 2012 Nov; 13(7):564-71. PMID: 22642603.
      Citations: 20     Fields:    Translation:HumansCells
    90. Sekhar RV, Jahoor F, Iyer D, Guthikonda A, Paranilam J, Elhaj F, Coraza I, Balasubramanyam A. Leptin replacement therapy does not improve the abnormal lipid kinetics of hypoleptinemic patients with HIV-associated lipodystrophy syndrome. Metabolism. 2012 Oct; 61(10):1395-403. PMID: 22542724.
      Citations: 9     Fields:    Translation:Humans
    91. McCaffery JM, Papandonatos GD, Peter I, Huggins GS, Raynor HA, Delahanty LM, Cheskin LJ, Balasubramanyam A, Wagenknecht LE, Wing RR, Genetic Subgroup of Look AHEAD, Look AHEAD Research Group. Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. Am J Clin Nutr. 2012 Jun; 95(6):1477-86. PMID: 22513296; PMCID: PMC3349457.
      Citations: 53     Fields:    Translation:Humans
    92. Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM, Look AHEAD Research Group, DIAGRAM consortium, Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Bhatt D, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, Asselbergs F, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ, B?hm BO, Silbernagel G, M?rz W. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet. 2012 Mar 09; 90(3):410-25. PMID: 22325160; PMCID: PMC3309185.
      Citations: 148     Fields:    Translation:Humans
    93. Gutierrez AD, Balasubramanyam A. Dysregulation of glucose metabolism in HIV patients: epidemiology, mechanisms, and management. Endocrine. 2012 Feb; 41(1):1-10. PMID: 22134974; PMCID: PMC3417129.
      Citations: 36     Fields:    Translation:Humans
    94. Couturier J, Patel SG, Iyer D, Balasubramanyam A, Lewis DE. Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBP? mRNA. Obesity (Silver Spring). 2012 Feb; 20(2):253-62. PMID: 21869759; PMCID: PMC4364279.
      Citations: 2     Fields:    Translation:HumansCells
    95. Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. Am J Clin Nutr. 2011 Sep; 94(3):847-53. PMID: 21795440; PMCID: PMC3155927.
      Citations: 98     Fields:    Translation:HumansCellsCTClinical Trials
    96. Smart-Halajko MC, Kelley-Hedgepeth A, Montefusco MC, Cooper JA, Kopin A, McCaffrey JM, Balasubramanyam A, Pownall HJ, Nathan DM, Peter I, Talmud PJ, Huggins GS, Look AHEAD Study. ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial. BMC Med Genet. 2011 Jun 29; 12:89. PMID: 21714923; PMCID: PMC3146919.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    97. Balasubramanyam A, Coraza I, Smith EO, Scott LW, Patel P, Iyer D, Taylor AA, Giordano TP, Sekhar RV, Clark P, Cuevas-Sanchez E, Kamble S, Ballantyne CM, Pownall HJ. Combination of niacin and fenofibrate with lifestyle changes improves dyslipidemia and hypoadiponectinemia in HIV patients on antiretroviral therapy: results of "heart positive," a randomized, controlled trial. J Clin Endocrinol Metab. 2011 Jul; 96(7):2236-47. PMID: 21565796; PMCID: PMC3135191.
      Citations: 26     Fields:    Translation:Humans
    98. Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, Jahoor F. Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care. 2011 Jan; 34(1):162-7. PMID: 20929994; PMCID: PMC3005481.
      Citations: 118     Fields:    Translation:Humans
    99. Sekhar RV, Patel SG, D'Amico S, Shi J, Balasubramanyam A, Rehman K, Jahoor F, Visnegarwala F. Effects of rosiglitazone on abnormal lipid kinetics in HIV-associated dyslipidemic lipodystrophy: a stable isotope study. Metabolism. 2011 Jun; 60(6):754-60. PMID: 20832829.
      Citations: 3     Fields:    Translation:HumansCells
    100. Sekhar RV, Balasubramanyam A. Treatment of dyslipidemia in HIV-infected patients. Expert Opin Pharmacother. 2010 Aug; 11(11):1845-54. PMID: 20486828.
      Citations: 3     Fields:    Translation:Humans
    101. Nalini R, Ozer K, Maldonado M, Patel SG, Hampe CS, Guthikonda A, Villanueva J, O'Brian Smith E, Gaur LK, Balasubramanyam A. Presence or absence of a known diabetic ketoacidosis precipitant defines distinct syndromes of "A-?+" ketosis-prone diabetes based on long-term ?-cell function, human leukocyte antigen class II alleles, and sex predilection. Metabolism. 2010 Oct; 59(10):1448-55. PMID: 20170930; PMCID: PMC2888957.
      Citations: 15     Fields:    Translation:HumansCells
    102. Misra R, Patel T, Kotha P, Raji A, Ganda O, Banerji M, Shah V, Vijay K, Mudaliar S, Iyer D, Balasubramanyam A. Prevalence of diabetes, metabolic syndrome, and cardiovascular risk factors in US Asian Indians: results from a national study. J Diabetes Complications. 2010 May-Jun; 24(3):145-53. PMID: 19303333.
      Citations: 60     Fields:    Translation:Humans
    103. Haaland WC, Scaduto DI, Maldonado MR, Mansouri DL, Nalini R, Iyer D, Patel S, Guthikonda A, Hampe CS, Balasubramanyam A, Metzker ML. A-beta-subtype of ketosis-prone diabetes is not predominantly a monogenic diabetic syndrome. Diabetes Care. 2009 May; 32(5):873-7. PMID: 19228875; PMCID: PMC2671096.
      Citations: 14     Fields:    Translation:HumansCells
    104. Balasubramanyam A. Intensive glycemic control in the intensive care unit: promises and pitfalls. J Clin Endocrinol Metab. 2009 Feb; 94(2):416-7. PMID: 19193915.
      Citations: 1     Fields:    Translation:Humans
    105. Nalini R, Gaur LK, Maldonado M, Hampe CS, Rodriguez L, Garza G, Lernmark A, Balasubramanyam A. HLA class II alleles specify phenotypes of ketosis-prone diabetes. Diabetes Care. 2008 Jun; 31(6):1195-200. PMID: 18316396; PMCID: PMC10027360.
      Citations: 14     Fields:    Translation:Humans
    106. Balasubramanyam A, Nalini R, Hampe CS, Maldonado M. Syndromes of ketosis-prone diabetes mellitus. Endocr Rev. 2008 May; 29(3):292-302. PMID: 18292467; PMCID: PMC2528854.
      Citations: 55     Fields:    Translation:HumansCells
    107. Nalini R, Maldonado M, Balasubramanyam A. Re: A comparison of classification schemes for ketosis-prone diabetes. Nat Clin Pract Endocrinol Metab. 2007 Dec; 3(12):E1. PMID: 18026157.
      Citations:    Fields:    Translation:Humans
    108. Lichtenstein K, Balasubramanyam A, Sekhar R, Freedland E. HIV-associated adipose redistribution syndrome (HARS): definition, epidemiology and clinical impact. AIDS Res Ther. 2007 Jul 16; 4:16. PMID: 17634130; PMCID: PMC1988803.
      Citations: 4     Fields:    
    109. Lichtenstein K, Balasubramanyam A, Sekhar R, Freedland E. HIV-associated adipose redistribution syndrome (HARS): etiology and pathophysiological mechanisms. AIDS Res Ther. 2007 Jun 27; 4:14. PMID: 17597538; PMCID: PMC1934375.
      Citations: 5     Fields:    
    110. Fareau GG, Maldonado M, Oral E, Balasubramanyam A. Regression of acanthosis nigricans correlates with disappearance of anti-insulin receptor autoantibodies and achievement of euglycemia in type B insulin resistance syndrome. Metabolism. 2007 May; 56(5):670-5. PMID: 17445543.
      Citations: 11     Fields:    Translation:Humans
    111. Chang E, Sekhar R, Patel S, Balasubramanyam A. Dysregulated energy expenditure in HIV-infected patients: a mechanistic review. Clin Infect Dis. 2007 Jun 01; 44(11):1509-17. PMID: 17479951.
      Citations: 10     Fields:    Translation:HumansCells
    112. Balasubramanyam A, Garza G, Rodriguez L, Hampe CS, Gaur L, Lernmark A, Maldonado MR. Accuracy and predictive value of classification schemes for ketosis-prone diabetes. Diabetes Care. 2006 Dec; 29(12):2575-9. PMID: 17130187.
      Citations: 46     Fields:    Translation:Humans
    113. Hampe CS, Nalini R, Maldonado MR, Hall TR, Garza G, Iyer D, Balasubramanyam A. Association of amino-terminal-specific antiglutamate decarboxylase (GAD65) autoantibodies with beta-cell functional reserve and a milder clinical phenotype in patients with GAD65 antibodies and ketosis-prone diabetes mellitus. J Clin Endocrinol Metab. 2007 Feb; 92(2):462-7. PMID: 17090641.
      Citations: 10     Fields:    Translation:HumansCells
    114. Garcia JM, Iyer D, Poston WS, Marcelli M, Reeves R, Foreyt J, Balasubramanyam A. Rise of plasma ghrelin with weight loss is not sustained during weight maintenance. Obesity (Silver Spring). 2006 Oct; 14(10):1716-23. PMID: 17062800.
      Citations: 17     Fields:    Translation:Humans
    115. Balasubramanyam A, Mersmann H, Jahoor F, Phillips TM, Sekhar RV, Schubert U, Brar B, Iyer D, Smith EO, Takahashi H, Lu H, Anderson P, Kino T, Henklein P, Kopp JB. Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice. Am J Physiol Endocrinol Metab. 2007 Jan; 292(1):E40-8. PMID: 16882932.
      Citations: 16     Fields:    Translation:AnimalsCells
    116. Samson SL, Pownall HJ, Scott LW, Ballantyne CM, Smith EO, Sekhar RV, Balasubramanyam A. Heart positive: design of a randomized controlled clinical trial of intensive lifestyle intervention, niacin and fenofibrate for HIV lipodystrophy/dyslipidemia. Contemp Clin Trials. 2006 Dec; 27(6):518-30. PMID: 16914390.
      Citations: 6     Fields:    Translation:Humans
    117. Balasubramanyam A, Hinnen D, Polonsky W. Cardiovascular event prevention in the person with type 2 diabetes: case examples for identifying and treating multiple risks. Diabetes Educ. 2006 Jul-Aug; 32 Suppl 5:163S-173S; quiz 174S-177S. PMID: 16873585.
      Citations:    Fields:    Translation:Humans
    118. D'Amico S, Shi J, Sekhar RV, Jahoor F, Ellis KJ, Rehman K, Willis J, Maldonado M, Balasubramanyam A. Physiologic growth hormone replacement improves fasting lipid kinetics in patients with HIV lipodystrophy syndrome. Am J Clin Nutr. 2006 Jul; 84(1):204-11. PMID: 16825697.
      Citations: 7     Fields:    Translation:HumansCells
    119. Villalpando S, Gopal J, Balasubramanyam A, Bandi VP, Guntupalli K, Jahoor F. In vivo arginine production and intravascular nitric oxide synthesis in hypotensive sepsis. Am J Clin Nutr. 2006 Jul; 84(1):197-203. PMID: 16825696.
      Citations: 23     Fields:    Translation:Humans
    120. Iyer D, Chang D, Marx J, Wei L, Olson EN, Parmacek MS, Balasubramanyam A, Schwartz RJ. Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4516-21. PMID: 16537394; PMCID: PMC1450203.
      Citations: 31     Fields:    Translation:AnimalsCells
    121. Balasubramanyam A, Sekhar RV. HIV-associated lipodystrophy syndrome: an accelerated form of the metabolic syndrome of insulin resistance due to altered fat distribution. Res Initiat Treat Action. 2006; 12(1):5-11. PMID: 17153230.
      Citations: 2     Fields:    Translation:Humans
    122. Otiniano ME, Balasubramanyam A, Maldonado M. Presence of the metabolic syndrome distinguishes patients with ketosis-prone diabetes who have a Type 2 diabetic phenotype. J Diabetes Complications. 2005 Nov-Dec; 19(6):313-8. PMID: 16260347.
      Citations: 6     Fields:    Translation:Humans
    123. Sekhar RV, Goodman JC, Balasubramanyam A, Tatro JB, Mihaly E. Regulation of body weight by proopiomelanocortin peptides in humans: lessons from the Nelson syndrome. Ann Intern Med. 2005 Aug 02; 143(3):238-9. PMID: 16061931.
      Citations:    Fields:    Translation:Humans
    124. Sekhar RV, Jahoor F, Pownall HJ, Rehman K, Gaubatz J, Iyer D, Balasubramanyam A. Severely dysregulated disposal of postprandial triacylglycerols exacerbates hypertriacylglycerolemia in HIV lipodystrophy syndrome. Am J Clin Nutr. 2005 Jun; 81(6):1405-10. PMID: 15941894.
      Citations: 23     Fields:    Translation:HumansCells
    125. Paschali AA, Goodrick GK, Kalantzi-Azizi A, Papadatou D, Balasubramanyam A. Accelerometer feedback to promote physical activity in adults with type 2 diabetes: a pilot study. Percept Mot Skills. 2005 Feb; 100(1):61-8. PMID: 15773694.
      Citations: 11     Fields:    Translation:Humans
    126. Vasudevan AR, Balasubramanyam A. Thiazolidinediones: a review of their mechanisms of insulin sensitization, therapeutic potential, clinical efficacy, and tolerability. Diabetes Technol Ther. 2004 Dec; 6(6):850-63. PMID: 15684639.
      Citations: 24     Fields:    Translation:Humans
    127. Visnegarwala F, Maldonado M, Sajja P, Minihan JL, Rodriguez-Barradas MC, Ong O, Lahart CJ, Hasan MQ, Balasubramanyam A, White AC. Lipid lowering effects of statins and fibrates in the management of HIV dyslipidemias associated with antiretroviral therapy in HIV clinical practice. J Infect. 2004 Nov; 49(4):283-90. PMID: 15474625.
      Citations: 12     Fields:    Translation:Humans
    128. Rao A, D'Amico S, Balasubramanyam A, Maldonado M. Fenofibrate is effective in treating hypertriglyceridemia associated with HIV lipodystrophy. Am J Med Sci. 2004 Jun; 327(6):315-8. PMID: 15201643.
      Citations: 13     Fields:    Translation:Humans
    129. Sekhar RV, Jahoor F, Pownall HJ, Ballantyne CM, Balasubramanyam A. Cardiovascular implications of HIV-associated dyslipidemic lipodystrophy. Curr Atheroscler Rep. 2004 May; 6(3):173-9. PMID: 15068741.
      Citations: 6     Fields:    Translation:Humans
    130. Balasubramanyam A, Maldonado M. Novel syndromes of ketosis-prone diabetes: implications for management and medical economics. Manag Care. 2004 Apr; 13(4 Suppl):7-10; discussion 19-21. PMID: 15156714.
      Citations:    Fields:    Translation:Humans
    131. Maldonado MR, Otiniano ME, Lee R, Rodriguez L, Balasubramanyam A. Characteristics of ketosis-prone diabetes in a multiethnic indigent community. Ethn Dis. 2004; 14(2):243-9. PMID: 15132210.
      Citations: 7     Fields:    Translation:Humans
    132. Shi J, Sekhar RV, Balasubramanyam A, Ellis K, Reeds PJ, Jahoor F, Sharma MD. Short- and long-term effects of growth hormone (GH) replacement on protein metabolism in GH-deficient adults. J Clin Endocrinol Metab. 2003 Dec; 88(12):5827-33. PMID: 14671176.
      Citations: 4     Fields:    Translation:HumansCells
    133. Maldonado M, Hampe CS, Gaur LK, D'Amico S, Iyer D, Hammerle LP, Bolgiano D, Rodriguez L, Rajan A, Lernmark A, Balasubramanyam A. Ketosis-prone diabetes: dissection of a heterogeneous syndrome using an immunogenetic and beta-cell functional classification, prospective analysis, and clinical outcomes. J Clin Endocrinol Metab. 2003 Nov; 88(11):5090-8. PMID: 14602731.
      Citations: 76     Fields:    Translation:Humans
    134. Maldonado MR, Otiniano ME, Lee R, Rodriguez L, Balasubramanyam A. Ethnic differences in beta-cell functional reserve and clinical features in patients with ketosis-prone diabetes. Diabetes Care. 2003 Aug; 26(8):2469. PMID: 12882882.
      Citations: 6     Fields:    Translation:Humans
    135. Scott LW, Balasubramanyam A, Kimball KT, Aherns AK, Fordis CM, Ballantyne CM. Long-term, randomized clinical trial of two diets in the metabolic syndrome and type 2 diabetes. Diabetes Care. 2003 Aug; 26(8):2481-2. PMID: 12882894.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    136. Iyer D, Belaguli N, Rowan BG, Wei L, Weigel NL, Booth FW, Epstein HF, Schwartz RJ, Balasubramanyam A, Fl?ck M. Novel phosphorylation target in the serum response factor MADS box regulates alpha-actin transcription. Biochemistry. 2003 Jun 24; 42(24):7477-86. PMID: 12809504.
      Citations: 11     Fields:    Translation:AnimalsCells
    137. Maldonado MR, Chong ER, Oehl MA, Balasubramanyam A. Economic impact of diabetic ketoacidosis in a multiethnic indigent population: analysis of costs based on the precipitating cause. Diabetes Care. 2003 Apr; 26(4):1265-9. PMID: 12663608.
      Citations: 35     Fields:    Translation:Humans
    138. Maldonado MR, D'Amico S, Rodriguez L, Iyer D, Balasubramanyam A. Improved outcomes in indigent patients with ketosis-prone diabetes: effect of a dedicated diabetes treatment unit. Endocr Pract. 2003 Jan-Feb; 9(1):26-32. PMID: 12917089.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    139. Stringer JL, Belaguli NS, Iyer D, Schwartz RJ, Balasubramanyam A. Developmental expression of serum response factor in the rat central nervous system. Brain Res Dev Brain Res. 2002 Sep 20; 138(1):81-6. PMID: 12234660.
      Citations: 9     Fields:    Translation:AnimalsCells
    140. Sekhar RV, Jahoor F, White AC, Pownall HJ, Visnegarwala F, Rodriguez-Barradas MC, Sharma M, Reeds PJ, Balasubramanyam A. Metabolic basis of HIV-lipodystrophy syndrome. Am J Physiol Endocrinol Metab. 2002 Aug; 283(2):E332-7. PMID: 12110539.
      Citations: 41     Fields:    Translation:HumansCells
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