"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
|
| MeSH Number(s) |
G02.111.570.120
|
| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 40 | 40 |
| 1995 | 0 | 46 | 46 |
| 1996 | 1 | 66 | 67 |
| 1997 | 0 | 77 | 77 |
| 1998 | 0 | 61 | 61 |
| 1999 | 0 | 58 | 58 |
| 2000 | 0 | 66 | 66 |
| 2001 | 0 | 64 | 64 |
| 2002 | 1 | 75 | 76 |
| 2003 | 0 | 84 | 84 |
| 2004 | 1 | 76 | 77 |
| 2005 | 1 | 64 | 65 |
| 2006 | 1 | 64 | 65 |
| 2007 | 0 | 49 | 49 |
| 2008 | 0 | 39 | 39 |
| 2009 | 1 | 49 | 50 |
| 2010 | 1 | 56 | 57 |
| 2011 | 0 | 56 | 56 |
| 2012 | 0 | 48 | 48 |
| 2013 | 3 | 59 | 62 |
| 2014 | 0 | 34 | 34 |
| 2015 | 0 | 40 | 40 |
| 2016 | 0 | 46 | 46 |
| 2017 | 1 | 36 | 37 |
| 2018 | 1 | 39 | 40 |
| 2019 | 1 | 36 | 37 |
| 2020 | 1 | 25 | 26 |
| 2021 | 0 | 31 | 31 |
| 2022 | 0 | 9 | 9 |
| 2023 | 0 | 11 | 11 |
| 2024 | 0 | 6 | 6 |
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click here.
Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD. Nucleic Acids Res. 2024 Aug 12; 52(14):8039-8051.
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Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity. J Med Chem. 2024 Jun 27; 67(12):10012-10024.
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The impact of von Willebrand factor on fibrin formation and structure unveiled with type 3 von Willebrand disease plasma. Blood Coagul Fibrinolysis. 2024 Jul 01; 35(5):256-264.
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Updated understanding of the protein-DNA recognition code used by C2H2 zinc finger proteins. Curr Opin Struct Biol. 2024 Aug; 87:102836.
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Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J Med Chem. 2024 May 23; 67(10):8186-8200.
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Repression of Acinetobacter baumannii DNA damage response requires DdrR-assisted binding of UmuDAb dimers to atypical SOS box. J Bacteriol. 2024 06 20; 206(6):e0043223.
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Molecular Basis for SPINDOC-Spindlin1 Engagement and Its Role in Transcriptional Attenuation. J Mol Biol. 2024 Apr 01; 436(7):168371.
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A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity. Nat Commun. 2023 10 16; 14(1):6516.
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Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature. 2023 Oct; 622(7982):376-382.
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Structures of CTCF-DNA complexes including all 11 zinc fingers. Nucleic Acids Res. 2023 09 08; 51(16):8447-8462.