"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 18 | 18 |
| 1996 | 0 | 11 | 11 |
| 1997 | 0 | 18 | 18 |
| 1998 | 0 | 16 | 16 |
| 1999 | 0 | 21 | 21 |
| 2000 | 0 | 30 | 30 |
| 2001 | 0 | 36 | 36 |
| 2002 | 1 | 27 | 28 |
| 2003 | 0 | 46 | 46 |
| 2004 | 0 | 45 | 45 |
| 2005 | 1 | 54 | 55 |
| 2006 | 1 | 55 | 56 |
| 2007 | 0 | 54 | 54 |
| 2008 | 0 | 54 | 54 |
| 2009 | 1 | 46 | 47 |
| 2010 | 1 | 61 | 62 |
| 2011 | 0 | 64 | 64 |
| 2012 | 0 | 44 | 44 |
| 2013 | 0 | 69 | 69 |
| 2014 | 1 | 61 | 62 |
| 2015 | 0 | 65 | 65 |
| 2016 | 1 | 53 | 54 |
| 2017 | 0 | 65 | 65 |
| 2018 | 0 | 52 | 52 |
| 2019 | 0 | 51 | 51 |
| 2020 | 0 | 53 | 53 |
| 2021 | 0 | 42 | 42 |
| 2022 | 0 | 10 | 10 |
| 2023 | 0 | 5 | 5 |
| 2024 | 1 | 15 | 16 |
| 2025 | 0 | 19 | 19 |
To return to the timeline,
click here.
Below are the most recent publications written about "Protein Binding" by people in Profiles.
-
GALNTL5 binds GalNAc and is required for migration through the uterotubal junction and sperm-zona pellucida binding. Nat Commun. 2025 Sep 17; 16(1):8264.
-
Structural elucidation of a unique binding mode by an intact alphavirus human IgG molecule to a quaternary epitope. Nat Commun. 2025 Aug 19; 16(1):7716.
-
Sliding Window Interaction Grammar (SWING): a generalized interaction language model for peptide and protein interactions. Nat Methods. 2025 Aug; 22(8):1707-1719.
-
Characterization of the ligand binding pocket of the virulence regulator Rns, a member of the AraC/XylS family of transcription factors. mSphere. 2025 Aug 26; 10(8):e0011525.
-
?-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21; 85(16):3041-3056.e9.
-
Disruption of the Nucleolin-CXCR4 interaction by the DNA aptamer HY-4 halts colorectal cancer metastasis. Mol Ther. 2025 Oct 01; 33(10):4904-4922.
-
Detecting Protein-DNA binding in single molecules using antibody guided methylation. Epigenetics Chromatin. 2025 Jul 01; 18(1):39.
-
CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage. Nat Commun. 2025 Jul 01; 16(1):5848.
-
A hierarchy of PDZ domain scaffolding proteins clusters the Kv1 K+ channel protein complex at the axon initial segment. Sci Adv. 2025 May 23; 11(21):eadv1281.
-
Structural proteomics defines a sequential priming mechanism for the progesterone receptor. Nat Commun. 2025 May 12; 16(1):4403.