"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 19 | 19 |
| 1996 | 0 | 11 | 11 |
| 1997 | 0 | 17 | 17 |
| 1998 | 0 | 17 | 17 |
| 1999 | 0 | 20 | 20 |
| 2000 | 0 | 28 | 28 |
| 2001 | 0 | 33 | 33 |
| 2002 | 1 | 25 | 26 |
| 2003 | 0 | 43 | 43 |
| 2004 | 0 | 44 | 44 |
| 2005 | 1 | 51 | 52 |
| 2006 | 1 | 55 | 56 |
| 2007 | 0 | 53 | 53 |
| 2008 | 0 | 55 | 55 |
| 2009 | 1 | 45 | 46 |
| 2010 | 1 | 57 | 58 |
| 2011 | 0 | 63 | 63 |
| 2012 | 0 | 39 | 39 |
| 2013 | 0 | 70 | 70 |
| 2014 | 0 | 58 | 58 |
| 2015 | 0 | 62 | 62 |
| 2016 | 0 | 53 | 53 |
| 2017 | 0 | 65 | 65 |
| 2018 | 0 | 46 | 46 |
| 2019 | 0 | 48 | 48 |
| 2020 | 0 | 50 | 50 |
| 2021 | 0 | 36 | 36 |
| 2022 | 0 | 6 | 6 |
| 2023 | 0 | 6 | 6 |
| 2024 | 1 | 9 | 10 |
| 2025 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Androgen receptor ubiquitination links KCTD13 to genitourinary tract defects. FASEB J. 2025 Feb 28; 39(4):e70406.
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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins. Proc Natl Acad Sci U S A. 2025 Feb 25; 122(8):e2420961122.
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Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding. ACS Infect Dis. 2025 Feb 14; 11(2):442-452.
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NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J. 2025 Feb; 44(4):1220-1248.
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Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling. Nucleic Acids Res. 2025 Jan 11; 53(2).
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DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders. Am J Hum Genet. 2025 Feb 06; 112(2):394-413.
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DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations. Nucleic Acids Res. 2024 Oct 28; 52(19):11442-11454.
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Fluorescence lifetime sorting reveals tunable enzyme interactions within cytoplasmic condensates. J Cell Biol. 2025 Jan 06; 224(1).
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Identification of an ionic mechanism for ERa-mediated rapid excitation in neurons. Sci Adv. 2024 Oct 04; 10(40):eadp0696.
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Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nat Commun. 2024 Oct 01; 15(1):8511.