"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 18 | 18 |
| 1996 | 0 | 11 | 11 |
| 1997 | 0 | 18 | 18 |
| 1998 | 0 | 17 | 17 |
| 1999 | 0 | 21 | 21 |
| 2000 | 0 | 29 | 29 |
| 2001 | 0 | 35 | 35 |
| 2002 | 1 | 26 | 27 |
| 2003 | 0 | 45 | 45 |
| 2004 | 0 | 45 | 45 |
| 2005 | 1 | 51 | 52 |
| 2006 | 1 | 54 | 55 |
| 2007 | 0 | 53 | 53 |
| 2008 | 0 | 55 | 55 |
| 2009 | 1 | 43 | 44 |
| 2010 | 1 | 58 | 59 |
| 2011 | 0 | 63 | 63 |
| 2012 | 0 | 39 | 39 |
| 2013 | 0 | 69 | 69 |
| 2014 | 0 | 59 | 59 |
| 2015 | 0 | 63 | 63 |
| 2016 | 0 | 50 | 50 |
| 2017 | 0 | 61 | 61 |
| 2018 | 0 | 45 | 45 |
| 2019 | 0 | 49 | 49 |
| 2020 | 0 | 50 | 50 |
| 2021 | 0 | 37 | 37 |
| 2022 | 0 | 7 | 7 |
| 2023 | 0 | 5 | 5 |
| 2024 | 1 | 11 | 12 |
| 2025 | 0 | 11 | 11 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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A hierarchy of PDZ domain scaffolding proteins clusters the Kv1 K+ channel protein complex at the axon initial segment. Sci Adv. 2025 May 23; 11(21):eadv1281.
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Structural proteomics defines a sequential priming mechanism for the progesterone receptor. Nat Commun. 2025 May 12; 16(1):4403.
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Fc?R binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein. Sci Transl Med. 2025 Apr 23; 17(795):eadk6745.
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Purification and biochemical characterization of mutant ligand binding domain of human estrogen receptor a protein. J Steroid Biochem Mol Biol. 2025 Jul; 251:106763.
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A putative binding model of nitazene derivatives at the ?-opioid receptor. Neuropharmacology. 2025 Aug 01; 273:110437.
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Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms. Mol Cell. 2025 Apr 03; 85(7):1445-1466.e13.
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Functional and antigenic landscape of the Nipah virus receptor-binding protein. Cell. 2025 May 01; 188(9):2480-2494.e22.
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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins. Proc Natl Acad Sci U S A. 2025 Feb 25; 122(8):e2420961122.
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Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding. ACS Infect Dis. 2025 Feb 14; 11(2):442-452.
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NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J. 2025 Feb; 44(4):1220-1248.