"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 10 | 10 |
| 1997 | 0 | 16 | 16 |
| 1998 | 0 | 15 | 15 |
| 1999 | 0 | 19 | 19 |
| 2000 | 0 | 29 | 29 |
| 2001 | 0 | 35 | 35 |
| 2002 | 1 | 27 | 28 |
| 2003 | 0 | 43 | 43 |
| 2004 | 0 | 40 | 40 |
| 2005 | 1 | 51 | 52 |
| 2006 | 1 | 53 | 54 |
| 2007 | 0 | 53 | 53 |
| 2008 | 0 | 50 | 50 |
| 2009 | 1 | 45 | 46 |
| 2010 | 1 | 58 | 59 |
| 2011 | 1 | 59 | 60 |
| 2012 | 0 | 41 | 41 |
| 2013 | 0 | 66 | 66 |
| 2014 | 1 | 62 | 63 |
| 2015 | 0 | 65 | 65 |
| 2016 | 1 | 50 | 51 |
| 2017 | 0 | 67 | 67 |
| 2018 | 0 | 45 | 45 |
| 2019 | 0 | 49 | 49 |
| 2020 | 0 | 51 | 51 |
| 2021 | 0 | 44 | 44 |
| 2022 | 0 | 9 | 9 |
| 2023 | 0 | 3 | 3 |
| 2024 | 1 | 14 | 15 |
| 2025 | 0 | 21 | 21 |
| 2026 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Progress and challenges in profiling protein-RNA and protein-associated RNA-RNA interactions. RNA. 2026 03 16; 32(4):457-471.
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Fyn-Saracatinib Complex Structure Reveals an Active State-like Conformation. Int J Mol Sci. 2026 Jan 23; 27(3).
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Characterizing the interactions between murine cytomegalovirus M72 and the carbon catabolite repression 4-negative on TATA-less (CCR4-NOT) complex. Virology. 2026 Mar; 616:110791.
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Computational Ligand-Binding Site Prediction. Adv Exp Med Biol. 2026; 1496:193-216.
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Mutational analysis of human norovirus VP2 elucidates critical molecular interactions for virus assembly. J Virol. 2026 02 17; 100(2):e0142025.
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Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity. Biochem J. 2025 Dec 03; 482(23).
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MeCP2 interacts with the super elongation complex to regulate transcription. Sci Adv. 2025 Nov 28; 11(48):eadt5937.
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Functional diversity in GII.4 norovirus entry: HBGA binding and capsid clustering dynamics. Proc Natl Acad Sci U S A. 2025 Oct 07; 122(40):e2517493122.
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COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale. Nat Commun. 2025 Sep 30; 16(1):8373.
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GALNTL5 binds GalNAc and is required for migration through the uterotubal junction and sperm-zona pellucida binding. Nat Commun. 2025 Sep 17; 16(1):8264.