Organic Cation Transport Proteins
"Organic Cation Transport Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins involved in the transport of organic cations. They play an important role in the elimination of a variety of endogenous substances, xenobiotics, and their metabolites from the body.
| Descriptor ID |
D027701
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| MeSH Number(s) |
D12.776.157.530.450.250.812 D12.776.157.530.937.612 D12.776.543.585.450.250.812 D12.776.543.585.937.701
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Organic Cation Transport Proteins".
Below are MeSH descriptors whose meaning is more specific than "Organic Cation Transport Proteins".
This graph shows the total number of publications written about "Organic Cation Transport Proteins" by people in this website by year, and whether "Organic Cation Transport Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 3 | 0 | 3 |
| 2000 | 2 | 0 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Organic Cation Transport Proteins" by people in Profiles.
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Induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation. Science. 2023 06 16; 380(6650):eade0027.
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Targeting CDK4 overcomes EMT-mediated tumor heterogeneity and therapeutic resistance in KRAS-mutant lung cancer. JCI Insight. 2021 09 08; 6(17).
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Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies. PLoS Genet. 2019 09; 15(9):e1008208.
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Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels. Nat Commun. 2018 10 12; 9(1):4228.
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Two unrelated children with overlapping 6q25.3 deletions, motor speech disorders, and language delays. Am J Med Genet A. 2017 Oct; 173(10):2659-2669.
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Drosophila SLC22A Transporter Is a Memory Suppressor Gene that Influences Cholinergic Neurotransmission to the Mushroom Bodies. Neuron. 2016 05 04; 90(3):581-95.
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A mutation in SLC22A4 encoding an organic cation transporter expressed in the cochlea strial endothelium causes human recessive non-syndromic hearing loss DFNB60. Hum Genet. 2016 May; 135(5):513-524.
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SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE). Breast Cancer Res Treat. 2012 Jul; 134(1):101-15.
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Crohn's disease and genetic hitchhiking at IBD5. Mol Biol Evol. 2012 Jan; 29(1):101-11.
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Molecular spectrum of SLC22A5 (OCTN2) gene mutations detected in 143 subjects evaluated for systemic carnitine deficiency. Hum Mutat. 2010 Aug; 31(8):E1632-51.