"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
|
| MeSH Number(s) |
A08.637.200 A11.650.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 1 | 3 |
| 1997 | 0 | 2 | 2 |
| 1998 | 4 | 0 | 4 |
| 1999 | 1 | 1 | 2 |
| 2000 | 2 | 1 | 3 |
| 2001 | 3 | 4 | 7 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 1 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 3 | 0 | 3 |
| 2009 | 3 | 2 | 5 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 7 | 2 | 9 |
| 2013 | 8 | 1 | 9 |
| 2014 | 4 | 3 | 7 |
| 2015 | 6 | 0 | 6 |
| 2016 | 4 | 3 | 7 |
| 2017 | 3 | 3 | 6 |
| 2018 | 5 | 2 | 7 |
| 2019 | 4 | 4 | 8 |
| 2020 | 6 | 3 | 9 |
| 2021 | 11 | 0 | 11 |
| 2022 | 4 | 2 | 6 |
| 2023 | 6 | 1 | 7 |
| 2024 | 6 | 7 | 13 |
| 2025 | 6 | 2 | 8 |
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Below are the most recent publications written about "Astrocytes" by people in Profiles.
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PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia. Nature. 2025 Oct; 646(8087):1178-1186.
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A functional perspective on astrocyte heterogeneity. Trends Neurosci. 2025 Sep; 48(9):691-705.
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Development and diversity of astrocytes. Development. 2025 Jul 01; 152(13).
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Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions. Nature. 2025 Aug; 644(8078):1097-1106.
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Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles directing astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain. PLoS Pathog. 2025 Jun; 21(6):e1012733.
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Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity. Nature. 2025 Jul; 643(8070):219-229.
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Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication. Mol Neurodegener. 2025 May 03; 20(1):51.
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Oral vancomycin treatment alters levels of indole derivatives and secondary bile acids modulating the expression of mTOR pathway genes in astrocytes during EAE. Brain Behav Immun. 2025 Mar; 125:355-370.
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Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1. Cell Rep. 2025 01 28; 44(1):115121.
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Ketamine induces plasticity in a norepinephrine-astroglial circuit to promote behavioral perseverance. Neuron. 2025 Feb 05; 113(3):426-443.e5.